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Biomedical subjects

H Halle

Publications and source records attributed to H Halle.

51 records · Page 3Linked to original sources

[Improved diagnosis fetal erythroblastosis due to Rh factors by combination of spectrophotometry (delta E 450) and a modified amniotic fluid ratio].

154 tests of amniotic fluid of 70 rh-sensitized women, won by transabdominal amniocentesis in the time between the 28th and 39th week of gestation were analysed. Besides experiential carried out spectrophotometric after Liley (estimation of delta E 450) liquor ratio were scrutinized concerning its value of statement for antenatal diagnosis in 2 variations (original liquor ratio and liquor ratio II). An equivalent pertinent judgment of delta E450 and Original liquor ratio was won. The best results were obtained with liquor ratio II and the combination of this method with delta E450. For further improvement of diagnostic reliability 2 methods of amniotic fluid analysis should be combined.

Amniocentesis↗

[Clinical problems of premature labor. 2. Therapy of threatening and actual premature labor].

The therapy of imminent prematurity needs specific treatment of the respective illness. Moreover there are three fundamental measures: 1. To appease the patients and to applicate sedatives. 2. To carry out tokolysis with medicamentes. 3. To carry out cerclage operation in order to close the uterine mouth. These possibilities must be combined in various ways dependent from the success in every individual case. These measures also are suit in prophylaxis, for example in disorders of former pregnancies. All schemes of therapy adapted to the individual case. The dosis must be determined from the effect of therapy. A particular view point must be the hospitalisation between 28. and 32. week of pregnancy in cases of twins or placenta previa. Also in cases of early rupture of amnion prolongation of pregnancy must be aspired.

Diazepam↗

[Labor induction by intra-amniotic administration of prostaglandin F 2 alpha].

A report of intraamniotic application of prostaglandin F2alpha in 40 cases is given. There were 13 primiparous and 27 multiparous women. In 97,5% (39 cases) the artificial abortion or the opening of the cervical channel, which is necessary for the evacuation of the uterus, could be achieved. The average dose of prostaglandin F2alpha was 28,8 mg, the mean time for induction was 16 hours 14 minutes. The intraamniotic application of prostaglandin can be applied successfully for abortion in the second three months' time.

Abortion, Induced↗

[Nitroglycerin for intraoperative uterus relaxation in cesarean section. Results of a randomized clinical study].

Between June 1994 and July 1996, a prospective, randomized, double-blind clinical study was carried out on 97 patients scheduled for elective cesarean section under general anesthesia at the gynecology departments of the Virchow and Charité Hospitals (both university hospitals of the Humboldt University, Berlin) in order to test the efficacy of glycerol nitrate (GTN: syn.: nitroglycerin) as an intraoperative short-acting tocolytic agent to ease fetal extraction in cesarean section in comparison to a placebo. At the time of the uterine puncture incision, either 0.25 mg (n = 32 patients) or 0.5 mg (n = 34) of GTN or physiological saline (n = 31) was administered as an intravenous bolus. Maternal and fetal pulse rates and blood pressures were closely monitored. The authors developed a scale to evaluate the degree of decrease in uterine tone and the ease of fetal extraction. The statistical evaluation of these estimations revealed no significant easing of fetal extraction and no significant increase in the reduction of uterine tone after administration of both GTN dosages in comparison to the administration of placebo (p > 0.01). Easing of fetal extraction cannot be achieved with the administration of 0.25 or 0.5 mg GTN, at least not in elective cesarean sections of greater than 34 weeks of gestation.

Adult↗