Biomedical subjects

H Haga

Publications and source records attributed to H Haga.

130 records · Page 8Linked to original sources

PubMedDate not supplied

Predictors of all-cause mortality between ages 70 and 80: the Koganei study.

The present paper explores predictors of all-cause mortality based on a longitudinal multidisciplinary study of 422 community residents (197 men, 225 women) aged 69-71 years at baseline examination. The 422 subjects were followed up for 10 years (1976-1986), during which time 102 (59 men, 43 women) died. The Cox proportional hazards model was used to examine the effects of baseline variables on a time-dependent 10-year mortality. Body mass showed a U-shaped relationship to mortality in both sexes. Ex-drinking, current-smoking, history of stroke, history of diabetes mellitus, low ADL and ST and/or T changes in ECG had significant and direct effects on mortality in both sexes or either sex. Whereas, level of education, current-drinking, grip strength, visual retention, and serum albumin revealed significantly inverse relationships to mortality.

Journal Article↗

PubMedDate not supplied

Circumstances of injurious falls leading to medical care among elderly people living in a rural community.

The objective of the present study is to describe the circumstances of injurious falls leading to medical care among the elderly living in a rural community, which have never been reported comprehensively. From 1992 to 1993, an interview survey on falls was carried out every 3 months. Of the 1349 subjects aged 65 or more of Nakazato village in Japan, 1317 persons responded to the survey by a door-by-door interview. Two-hundred-and-fifty-six elderly people experienced a fall at least once during the 1-year period. One-hundred-and-twenty-four falls were recorded by 94 men and 215 falls were experienced by 162 women. In men, 16 (31.31/1000 person-year) injurious falls leading to medical care were documented. In women, 58 (75.74/1000 person-year) falls were found to be injurious. The difference in the rate of injurious falls between the sexes was statistically significant (P < 0.01). In each sex, there was no increased rate of injurious falls with advancing age. Most of the injurious falls occurred in the daytime. As for the location of injurious falls, outdoor falls were more frequent than indoor falls in the case of men. Half of the injurious falls in women occurred indoors. Extrinsic factors largely contributed to the occurrence of injurious falls compared with intrinsic ones. Women tended to be injured in the buttocks and hip in a greater proportion than men. This study reveals the circumstances of injurious falls leading to medical care and provides useful information on preventing injurious falls among the elderly living in the community.

Journal Article↗

PubMedDate not supplied

Successful emergency treatment with a transjugular intrahepatic portosystemic shunt for life-threatening Budd-Chiari syndrome with portal thrombotic obstruction.

We report successful treatment of acute severe Budd-Chiari syndrome with portal venous thrombosis. The prognosis of patients with this condition is poor, because the therapeutic options are limited. A 38-year-old woman with polycythemia vera was admitted in a critical condition, and Budd-Chiari syndrome complicated by portal venous thrombosis was diagnosed. Tissue plasminogen activator and urokinase were infused systemically and were partially effective. Transjugular intrahepatic portosystemic shunting to reduce the high portal venous pressure was performed successfully and, eventually, her general condition improved. Our experience indicates that emergency transjugular intrahepatic portosystemic shunting is an effective therapeutic modality for controlling portal hypertension in patients with severe Budd-Chiari syndrome with portal venous thrombosis.

Adult↗

PubMedDate not supplied

Clinical subgroup of autoimmune hepatitis type 1 sustaining remission without additional drugs.

BACKGROUND/AIMS: Many patients with autoimmune hepatitis type 1 need additional non-steroidal immunosuppressants to maintain remissions, but the indication should be limited to avoid the unnecessary side effects. The aim of this study is to clarify the clinical subgroups of autoimmune hepatitis type 1 sustaining remission without additional drugs. METHODOLOGY: We studied 20 patients with autoimmune hepatitis type 1, in whom complete remissions were achieved in the natural course or by prednisolone alone. Remissions were maintained with none or less than 10 mg/day of prednisolone. RESULTS: In the course (average: 6 years), 8 patients (40%) remained in remission for more than three years. In the remitted group, initial values of serum gamma-globulin (p<0.05) and serum immunoglobulin G (p<0.01) were lower than those in the relapsed group. The group with less than 30 mg/ml of gamma-globulin and 3000 mg/dl of immunoglobulin G showed a significantly lower relapse rate than the other one (p<0.01). CONCLUSIONS: There is a clinical subgroup of autoimmune hepatitis type 1 that sustains remission with low-dose prednisolone alone. Additional immunosuppressive drugs may not be needed to maintain remissions in such patients.

Anti-Inflammatory Agents↗