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Biomedical subjects

H H Vollhaber

Publications and source records attributed to H H Vollhaber.

13 recordsLinked to original sources

[Malignant pleural mesothelioma. Value of 67Ga scintigraphy compared to computerized tomography].

In 34 patients with suspected malignant pleural mesothelioma the results of computed tomography are compared with the findings of 67Ga-scintigraphy. The differential diagnosis of 14 pleural mesotheliomas, 7 pleural carcinoses, 10 inflammatory and 3 other pleural diseases is performed more accurately by CT than by scintigraphy. 67Ga uptake depends on the thickness of inflammatory as well as malignant lesions. Thus, numerous pleural processes that can be localised by CT escape scintigraphic detection. CT is indicated if there is clinical and radiological suspicion of pleural mesothelioma; in that case, there is hardly any indication for 67Ga scintigraphy.

Adult↗

Tumour volume and macroscopic growth pattern of bronchogenic carcinoma.

126 resected malignant lung tumours were cut into serial sections. The tumour volume, the pTN-stage and the macroscopic growth pattern were computed. The average tumour volume was found to be 28.5-35.8 cm3 (confidence limits, p greater than or equal to 95%) and to be independent of the major cell type of the carcinomas. The cell types grow in different macroscopically distinguishable tumour growth patterns: epidermoid carcinomas grow mostly in bizarre finger-like shapes and small cell anaplastic and adenocarcinomas more frequently in ball-like shapes. The different growth patterns depend on the cell type, the cellular response of the host tissue and the tumour volume. Due to irregular growth pattern the tumour volume computed by X-ray diameter is likely to be overestimated by 50%-300%.

Adenocarcinoma↗

[Computed tomographic and roentgenologic findings in bronchiolo-alveolar carcinoma of the lung].

Eighteen patients with alveolar carcinomas (ten solitary, eight disseminated) were examined pre-operatively by CT and conventional radiography and the results were compared. The 'pleura fingers' and air bronchogram were shown by conventional tomography as often as by CT in the solitary cases. In the disseminated form, CT is superior by showing small foci in the opposite lung.

Adenocarcinoma, Bronchiolo-Alveolar↗

Kr-81m for determination of right ventricular ejection fraction (RVEF).

A 10--12 mCi 81Rb leads to 81mKr generator was connected to a specially designed short-period infusion set, to produce an equilibrium activity distribution in the right heart. This procedure was tested in 25 individuals to calculate the right ventricular ejection fraction (RVEF). On average 30 heart cycles were analyzed per study. No background activity from the left heart was visualized because of the radionuclide exhalation. The background from the lungs could be neglected, which is partially due to the ultra-short half-life of the nuclide (t 1/2 = 13 S). Thus, an easy automatic procedure can be applied to delineate the ventricle and to calculate the RVEF. The data showed excellent reproducibility, when investigations were repeated. The method would benefit from use of higher activity generators.

Adult↗

[Lung biopsy].

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Biopsy, Needle↗