To assess the relationship between birth weight or birth length and the corresponding velocities of growth in infancy and childhood, 3995 subjects, followed longitudinally, were studied. Pearson correlations indicated no significant relationship between birth size and velocity in infancy, between birth size and velocity in childhood, or between velocities of growth in infancy and childhood. The only correlation that approached any significance suggested a tendency for subjects who gained weight faster in infancy to gain weight faster in childhood.

Birth Weight↗

PubMed1981

Linear regression to approximate longitudinal growth curves: revised standards for velocity of weight and length in infants.

Because of lack of acceptability of the previous log-linear model of slope velocity for the assessment of weight and length in children 1 to 36 months of age, a modified method for least squares determination of velocity of growth by slope has been designed. This model uses a compound logarithmic expression of time and a newly designed graphic scale. The acceptability of the graphic (hand-drawn) line is retained while "goodness of fit" of the model is improved. This improved model makes it possible to revise our standards for velocity of growth of children 1 to 36 months of age.

Anthropometry↗

PubMed1976

Structural aberrations of the long arm of chromosome no. 22. Report fo a family with translocation t(11;22) (q25;q11).

A chromosomal translocation t(11;22) (q25q11) is described in a family. Four members, in two generations, had the same translocation but showed phenotypic variation. Case reports of chromosome aberrations involving the long arm of chromosome 22 associated with and without chronic myeloid leukemia (CML) are reviewed. It appears that the distal segment of the long arm or chromosome 22 is either translocated or deleted, resulting in congenital anomalies, presumably due to chromosome imbalance. In other instances, a specific breakpoint on 22q results in the origin of Philadelphia chromosome (Ph1) associated with CML.

Abnormalities, Multiple↗

PubMed1973