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Biomedical subjects

H H Caffee

Publications and source records attributed to H H Caffee.

At least 37 records · Page 2Linked to original sources
PubMed1988

Postoperative radiation and implant capsule contraction.

Occasionally radiation is required as adjunctive therapy following mastectomy for breast cancer. The effects of radiation on a developing implant capsule are unknown, but they are very important in relation to the increased use of immediate reconstruction. Experiments were performed on rabbits to study the effects of postoperative radiation therapy on capsule contraction and thickness. The results of these experiments suggest that radiation has no effect on implant capsules.

Abnormalities, Radiation-Induced↗
PubMed1988

Breast cancer in a patient with silicone breast implants after 13 years.

The patient described in this article is a 45-year-old woman who developed an infiltrating ductal carcinoma in her left breast next to a Silastic mammary implant that had been used for augmentation some 13 years previously. She underwent a modified radical mastectomy and removal of the silicone prosthesis with an axillary lymph node dissection. Twenty-six axillary lymph nodes were negative for metastatic disease. The 165-gram silicone gel prosthesis was surrounded by a thin fibrous capsule with an attached 1-cm carcinoma that did not invade the fibrous capsule. It appeared that the capsule presented a barrier to the invading ductal carcinoma. The fibrous capsule surrounding the Silastic implant may have altered the spread of the breast cancer without being related to its genesis.

Breast↗
PubMed1988

Experiments on the effects of hyperbaric oxygen on flap survival in the pig.

The use of hyperbaric oxygen has been advocated as a method of improving survival of ischemic flaps. Experiments were done in the pig using modern flap designs and hyperbaric oxygen protocols that have been reported to be effective in rodents. The results of these experiments indicate that hyperbaric oxygen is not effective in improving flap survival in the pig.

Animals↗
PubMed1987

Vitamin E and capsule contracture.

Vitamin E is known to inhibit the inflammatory phase of wound healing and to decrease wound tensile strength. For these reasons, vitamin E has been suggested for the prevention of breast implant capsule contracture. Experiments in rabbits demonstrated a reduction in capsule contracture that was significant statistically, but the improvement was minor, suggesting that vitamin E prophylaxis would probably not have a major impact on the clinical problem of capsule contracture.

Animals↗
PubMed1986

Pulse oximetry for vascular monitoring in upper extremity replantation surgery.

Pulse oximetry as a postoperative monitor for replanted or revascularized digits was evaluated experimentally and clinically. The accuracy of detection of vascular occlusion was 100%, and arterial and venous occlusion could be differentiated by changes in pulse inflow and oxygen saturation. Digits demonstrating O2 saturations above 95% remained viable, those below 85% were associated with venous occlusions, and those with no saturation represented arterial occlusions. This method is simple, noninvasive, continuous, and accurate, and it reliably assesses revascularized digits and replanted parts.

Adult↗
PubMed1986

The effects of hematoma on implant capsules.

Hematoma surrounding an implant is one of the many factors that have been suggested as possible causes for scar capsule contracture. In this study, experiments were designed to determine the influence of hematoma on the incidence and severity of capsule contracture in rabbits. Two implants were placed in each animal, 1 with a surrounding hematoma and 1 control. Capsules were evaluated subjectively and compared objectively with measurements of deformability, surface area, and capsule thickness. No differences were found with any of the objective criteria, which suggests that hematoma may not be a noteworthy cause of implant capsule contracture.

Animals↗
PubMed1986

The influence of silicone bleed on capsule contracture.

The phenomenon of silicone bleed from breast implants has been recognized for several years, but its importance continues to be a source of controversy. Experiments were done in rabbits in which standard implants were compared with implants that had been modified to reduce silicone bleed. Contracture was seen with both types of implants, but both the incidence and severity were significantly reduced with the low bleed implants.

Animals↗
PubMed1986

Bipolar coagulation in microvascular surgery.

In microvascular surgery and surgery of the hand, hemostasis must be accomplished very precisely to avoid injury to adjacent structures. Bipolar coagulation is one of the more precise techniques, since theoretically, current flows only through tissue that is held between the tips of the forceps. Experiments were done in rats to confirm that bipolar coagulation can be used to control vessel branches without disturbing the parent vessel or adversely affecting an adjacent anastomosis. However, the importance of the characteristics of the bipolar generator require particular attention. The generator used in these experiments produces a continuous-sine-wave current to minimize voltage. In addition, the equipment was designed to sense impedance and to automatically shut down at the point of desiccation, thus avoiding sparking, charring, and adherence of tissue to the forceps.

Abdomen↗
PubMed1986

Computer applications in plastic surgery training programs.

In this article three simple applications for microcomputers in the training program setting are explained. All three are also useful in a private practice setting. The ability to conduct a literature search from your own office and the ability to manage lists of clinical cases have important research as well as educational advantages. The computerized in-service examination takes an already useful educational tool and adds a new dimension.

Computer-Assisted Instruction↗
PubMed1984

Atherosclerosis of the forearm and hand.

Three patients were treated for severe atherosclerotic obstructive disease in the upper extremity. In all three, vein bypass grafts were placed from the forearm to the superficial palmar arch. The grafts have remained patent for the period of follow-up between 8 and 18 months, and significant palliation was achieved.

Arteriosclerosis↗
PubMed1984

The effects of intraprosthetic methylprednisolone on implant capsules and surrounding soft tissue.

One of the many methods that have been suggested for the prevention of implant capsule contracture is the use of soluble steroids within the implant. In this study a range of concentrations of methylprednisolone hemisuccinate was tested in rabbits, and even the lowest concentration was found to be effective in the prevention of contracture. Higher concentrations were found to result in extremely large capsules. No atrophy of the skin over the implants was seen even with use of the highest concentrations of the steroid, but this may have been due to the short (five-month) interval between implant placement and measurement.

Animals↗
PubMed1983

The effect of stasis on a microvascular anastomosis.

An experiment was done in rats to determine the effect of stopping the flow of blood across a fresh anastomosis. It was found that brief periods of stasis, up to 30 minutes, caused a minimal increase in the rate of thrombosis, but 60 minutes of stasis caused a significant risk of thrombosis in both arteries and veins. The thrombosis associated with stasis could be prevented by the systemic administration of heparin.

Animals↗
PubMed1983

Vascularized omentum for facial contour restoration.

Our experience with the omental flap for facial soft-tissue augmentation in 7 patients is presented, along with our method of fixation of the graft to prevent gravitational descent. The history of the omental free flap, as well as the previously applied techniques for facial soft-tissue augmentation, is reviewed. It is our conclusion that the omental free flap is a safe, reliable technique. It can be readily molded to exactly conform to the patient's deformity and produces good results both in repose and during facial expression. We believe that gravitational descent of the graft can be prevented by the technique of multiple-suture fixation.

Adolescent↗
PubMed1983

Measurement of implant capsules.

A more direct measurement of implant capsule contracture is needed for the laboratory study of this phenomenon. Most of the previous methods for quantitation of contracture rely on measurements of deformability. Because contraction of an implant capsule is in fact a decrease in the surface area of the capsule, a method is proposed for the calculation of capsule surface area from measurements of height and base diameter.

Animals↗