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Biomedical subjects

H Guan

Publications and source records attributed to H Guan.

83 records · Page 5Linked to original sources

[Low dose heparin in the treatment of deep vein thrombosis].

From 1988 to 1990, 45 cases of lower extremity deep vein thrombosis (DVT) was confirmed by 99mTc radionuclide venography (RNV) at PUMC hospital. Each case was treated by subcutaneous injection of low dose heparin. 21 cases of the 45 cases had post-therapeutic RNV. The results were excellent in 19 cases (complete improvement: swelling, discolouration and pain disappeared), good in 18 cases (marked improvement) and poor in 8 cases (incomplete improvement). Low dose heparin subcutaneous injection can relieve symptoms of DVT and avoid bleeding complication.

Adult↗

[A report on 53 cases of Budd-Chiari syndrome].

Budd-Chiari syndrome is an unusual form of portal hypertension caused by liver cirrhosis. Its mortality rate exceeds 50% within 2 years. Surgical therapy provides superior survival rates than conservative medical management. During 1984-1989, 58 cases of Budd-Chiari syndrome were treated at PUMC hospital. The age of these patients ranged from 16 to 62. There were 39 males and 19 females. Diagnosis was mostly made by simultaneous inferior and superior Vena Cavography and one case was diagnosed by liver biopsy. Intraluminal pressure measurement of IVC and diameter measurement of IVC by Doppler ultrasound method were used for diagnosis. Preoperative intraluminal mean pressure of IVC in 26 cases was 3.2 +/- 0.6 kPa and it decreased to 1.9 +/- 0.6 kPa postoperatively. (P less than 0.01) Digital membranotomy through right atrium was done in 34 cases, percutaneous balloon catheter dilatation in 7 cases and Meso-atrial shunt, inferior Vena Cava Atrial shunt were performed in 20 cases. Postoperative improvement was found in 85% of the patients during the follow-up period (from 2-60 months).

Adolescent↗

[Severe brain stem ischemia caused by subclavian steal syndrome].

Subclavian steal syndrome (SSS) is produced by occlusion of the proximal subclavian artery and subsequent retrograde filling of the subclavian artery via the vertebral artery. The resulting alteration of blood flow may cause a variety of symptoms secondary to decreased blood supply to the brain and upper extremity of the affected side. A case of severe brain stem ischemia caused by SSS was reported. We performed a subclavian-subclavian graft shunt for this patient and obtained good results. Such a case has been only rarely described in the literature. Complementary information obtained from digital subtraction angiography, computed tomography and MRI helped to establish a correct preoperative and postoperative diagnosis.

Brain Ischemia↗

[Diagnosis and treatment of membraneous obstruction of the inferior vena cava].

From 1984 to 1989, 52 cases with Budd-Chiari syndrome were surgically treated at the PUMC Hospital. Among them there were 31 cases of membranous obstruction of the inferior vena cava (MOVC, 59.6%). There were 24 males and 7 females, ase ranging from 24 to 36 years. Diagnosis was confirmed by inferior venocavagraphy. According to Sugiura's Classification, there were type Ia and Ib in 26 cases, and type II in 5. Edema and varicosity on both legs, the chest, the abdomen, and the back were found in 93.5% (29/31), and hepatomegaly, splenomegaly, and large amount of ascites were found in 61.3% (19/31), 64.5% (20/31), and 54.8% (17/31), respectively. Transcardiac membranotomy was performed in 27 cases, and the remaining 4 cases were treated by percutaneous transluminal angioplasty using balloon catheters both without operative mortality. Four to sixty months' follow-up in 29 cases revealed satisfactory results. The authors belief that membranotomy can be successfully performed in cases of MOVC when the stricture is located well above the level of T-9th vertebra, and with a length of less than 2 cm.

Adult↗