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Biomedical subjects

H Graf

Publications and source records attributed to H Graf.

At least 163 records · Page 9Linked to original sources

[Supplementation of the amino acid composition of protein-rich wheat with protein concentrates and L-lysine in rations for laying hens. 4. Effect of various rearing diets on crude protein, fat and ash contents of the utilizable and nonutilizable parts of carcasses of slaughter hens].

The present paper is concerned with the effects of four rations of varying composition (fed to pullets from the eighth to the twenty-second week of life) on the composition of the carcasses of laying hens at the end of a 52-week trial. Ration 1 served as a control; ration 2 contained 68% protein-rich wheat as a protein carrier, 2% extracted soybean meal. 4% fish meal; the two other rations contained only 94% protein-rich wheat with or without addition of 2% lysine. The mean live-weights of the animals for slaughter were: 1792 g +/- 71 g; 1760 g +/- 78 g; 1701 g +/- 92 g; and 1655 +/- 102 g, respectively. The mean portion of edible parts (heart, liver, stomach, fatty tissue, follicles, flesh) of the 104 carcasses was 61.6% +/- 3.0%. The edible parts contained (mean values): crude protein, 18.0% +/- 2.0%; raw fat, 22.8% +/- 5.7%; and crude ash, 1.02% +/- 0.16%. The values calculated for the bonefree, uneatable parts (to be used as feed) were: crude protein, 16.2% +/- 0.7%; raw fat, 8.7% +/- 1.5%; and crude ash, 3.45% +/- 0.32%. The ash content of the edible parts is increased by lysine-rich diets. The rearing as well as the feeding during the laying period exerted no targeted effect on the crude protein and raw fat contents of the carcasses. The fat content of the carcass is determined by the consumption of energy.

Aging↗

Influence of parenteral fat administration on the pulmonary vascular system in man.

In 16 patients with multiple injuries the effect of parenteral administration of a fat emulsion on the pulmonary vascular system has been studied. Using the Hewlett Packard 5600 A Intensive Care System, which allows vital parameters to be sampled at a rate of two values per min, pulmonary artery pressure (PAP) was monitored before, during, and after the administration of Lipofundin S 20% (0.24 g/kg/h). In addition right ventricular stroke work index (RVSWI), alveolar-arterial oxygen difference (A-aDO2) and pulmonary shunt (Qs/Qt) were calculated. The results indicate that there are no changes of the PAP, the RVSWI, and the A-aDO2 during the period of observation.

Adult↗

Spontaneous arteriovenous plasma separation.

Plasmapheresis (PP) therapy was carried out by spontaneous arteriovenous membrane plasma separation. By cannulating the femoral artery and vein by Seldinger technique, this method could be performed by natural arteriovenous pressure gradient without blood pumps or special monitoring. Eight patients experienced 44 PP therapies without complication in the ICU. Spontaneous arteriovenous membrane plasma separation can suitably be combined with continuous arteriovenous hemofiltration.

Adult↗

Potential cariogenicity of low and high sucrose dietary patterns.

In vivo daytime plaque pH telemetry during 2 week periods was combined with measurement of changes in enamel microhardness and analysis of microbial plaque composition in 2 human subjects. Well defined sucrose rich and sucrose poor diets were used as variables. During the 2 weeks of the high sucrose diet (50-80 g/day), a high cariogenic acid attack calculated from pH changes in "Proton hours" was associated with a marked progressive decrease in enamel microhardness. The low sucrose diet (2-6 g/day) showed a low "Proton hour" acid attack during the entire 2 weeks. The decrease in enamel microhardness, however, was low only during the first week. After day 7 a marked decrease could be observed. It could not be explained by the glycolytic activity of the plaque, which was low. Streptococcus mutans was present in all microbial samples.

Aged↗

[3-dimensional approach to spinal deformities. Application to the study of the prognosis of pediatric scoliosis].

The authors have utilized a computer for a spatial analysis of deformities of the spine using antero-posterior and lateral radiographs. The posterior limits of the sacral plateau and the centre of each vertebral plateau was demarcated on the antero-posterior radiograph. The posterior margin of each vertebra was demarcated on the lateral radiograph. With this information, the computer can make a picture as if the spine were seen from above and vertebral rotation can be assessed. The vertebrae are of different colours according to their level. Thirty cases have been studied and six types of infantile scoliosis defined - scoliosis with a localised hyper-rotation like a hairpin, scoliosis with rotary dislocation at the junction of two rotational levels, infantile scoliosis with a moderate curve, progressive scoliosis, benign scoliosis and spontaneously regressive scoliosis of the newborn. This study was shown that prognostic features were in accordance with classical assessments.

Child↗

[ Fournier gangrene: a rare complication of multiple myeloma].

A 69-year-old male patient with multiple myeloma developed a dolent swelling of the right side of his scrotum at the time of maximal leukocyte depression after cytostatic drug therapy. Within a few hours the scrotal skin became gangrenous. After surgical debridement of the necrotic tissues and simultaneous antibiotic therapy the necrosis showed a favorable course.

Aged↗

[High-density-lipoprotein and renal insufficiency (author's transl)].

Disturbances in lipid metabolism and accelerated atherosclerosis are well-known phenomena of chronic renal insufficiency. The disturbance in lipid metabolism has been repeatedly described as secondary type IV hyperlipoproteinemia according to the classification of Fredrickson. The classification of Fredrickson, however, does not take into account the role of the alpha-lipoproteins (the HDL lipoproteins and HDL cholesterol). Hence, HDL cholesterol was determined and correlated to other routine parameters of lipid metabolism in 66 patients with different degrees of renal insufficiency. Furthermore, an intravenous fat tolerance test was performed in 14 patients with terminal renal insufficiency. Beside the well-known hypertriglyceridemia with cholesterol values near the upper limits of normal, a significant reduction in HDL cholesterol was found, showing a significant inverse correlation to plasma creatinine values. Patients with advanced or terminal renal insufficiency additionally showed a significant inverse correlation between HDL cholesterol and plasma triglycerides. The disappearance rate of intravenously administered fat emulsion (which corresponds to the clearance rate of chylomicrons and VLDL) was diminished in azotaemic patients, showing a significant inverse correlation between HDL cholesterol and disappearance rate in the intravenous FTT. Beside hypertriglyceridemia, the diminished HDL cholesterol values represent an additional risk factor for the genesis of accelerated atherosclerosis. The diminished k value demonstrates a diminished activity of lipoprotein lipase as cause of hypertriglyceridemia, whereby the positive correlation between the k value and HDL cholesterol and the inverse correlation between HDL cholesterol and triglycerides suggest a causal relationship between the decreased activity of lipoprotein lipase and diminished HDL cholesterol levels.

Arteriosclerosis↗

Metabolic nitrite formation from N-nitrosamines: evidence for a cytochrome P-450 dependent reaction.

Nitrite was formed on incubation of N-nitrosamines with a reconstituted monooxygenase system, consisting of cytochrome P-450 (P-450) and NADPH P-450 reductase from pig liver. Nitrite was not obtained when the nitrosamines were incubated with NADPH P-450 reductase alone or when molecular oxygen or NADPH were omitted. Interaction of nitrosamines with the reconstituted P-450 system or with hemoglobin under reducing conditions resulted in optical spectra identical with those obtained with nitrite. It is proposed that N-nitrosamines are denitrosated by electron transfer from the hemoprotein iron to the nitrosamine molecule.

Animals↗

[The Ender nailing : state of the art and new improvements. The sliding nailing (author's transl)].

The authors, as well as many other people, have encountered some misuses and complications of Ender nailing. Some surgical improvements are pointed out : reduction with a slight valgus, meticulous digging of the hole, sagital precurving of the nails, careful selection of loading criteria. A new device is also described from the Ender nail, that they modified : an Ender nail with a distal screwing slide which allows distal screwing and therefore prevents going down and rotation of the nails. A case study of three comparative series showed the substantial progress which was made possible by these technical improvements, and most of all by the distal sliding screwing.

Aged↗