Biomedical subjects

H Goldmann

Publications and source records attributed to H Goldmann.

At least 19 recordsLinked to original sources

PubMed1979

Rapid detection of changes in the optic disc: stereochronoscopy. III. Retinal venous pulse as an interfering factor.

In the evaluation of stereochronoscopic pairs of fundus pictures (Sc) venous pulse is an interfering factor. Visual observation and photography show that when a magnification of 15x is used, as in our case, venous pulse is seen only at the emerging part of the big veins and in their immediate neighborhood, whereas veins of 100 microns diameter or less show no pulsation. Over relatively short time intervals (some minutes) the temporal course of venous pulse in terms of vessel width is a more or less periodic phenomenon; for longer periods (months) a study is underway. In the majority of cases the filling state of pulsating veins seems to reach a minimum shortly after the R peak of the ECG. An investigation as to whether the interference of venous pulse can be reduced by coupling the camera flash to the R peak has been begun. However, for the time being, it appears that the best method is to pass over the pulsating vessel parts, and to observe Sc effects only in the small vessels, when Sc evaluation is applied. Statistics show that venous pulse is significantly more frequent in suspected and early glaucoma subjects (T greater than 21 mm appl.) than in healthy subjects. We feel that with the methods proposed all conditions pertaining to an extensive follow-up of ocular hypertension and early glaucoma cases are now established.

Adult↗

PubMed1978

Rapid detection of changes in the optic disc: stereochronoscopy. II. Evaluation technique, influence of some physiologic factors, and follow-up of a case of choked disc.

A simple device for viewing stereochronoscopic (Sc) picture pairs under any azimuth is described. The influence of pulse, irradiation, time, and ocular pressure on disc configuration of some healthy and affected subjects is investigated. To test the sensitivity of Sc as compared to that of conventional steroscopy (St), a case of choked disc in which pictures of both kinds had been taken was followed up. This material also served to test 10 observers as to their ability to detect St and Sc effects in fundus pictures. Despite good stereo vision in all observers as tested by the Titmus charts, considerable differences were found in the analysis of fundus pictures. Detailed instruction resulted in improved results. Two cases of glaucoma simplex incipiens are presented in which a change of disc configuration could be detected by SC while ocular pressure and visual field remained normal in one case and did not change in the other.

Adult↗

PubMed1978

[Temporal change of the disc in normal adults (author's transl)].

We have recently proposed a procedure called stereochronoscopy which allows the detection of temporal changes in the disc by stereoscopic observation of exactly centered fundus pictures. We show that this procedure can also be applied in a slightly modified form to fundus pictures that are not specially centered, although with less precision. Using this technique we were able to show on material covering 10 years (50 eyes) that the discs of healthy adults do not as a rule change over a period of at least 8 years. This is valid for observation of the pictures with an overall magnification of X 14.

Adult↗

PubMed1977

Rapid detection of changes in the optic disc: stereo-chronoscopy.

Easy detection of temporal variations of tissue configurations within the optic disc or other structures is possible by means of stereoscopy: Stereochronoscopy. Photographic pictures of the papilla are taken from time to time at exactly the same angle; when any two of them are paired and viewed with a stereoscope, temporal form changes immediately show up as stereo effects (Schirmer [2]). Since continuing glaucomatous damage cannot be diagnosed either by visual field defects or by actual c/d ratios but only by their temporal changes, this method may prove of diagnostic value.

Adult↗

PubMed1976

Fluorescein in the human optic disc. II. The fluorescein appearance rate.

Automatic intravenous infusion of fluorescein with constant speed during 25 sec is followed by a gradual increase of fluorescein in the retinal arteries and in the disc tissue. The slope of this increase Sd divided by the maximum fluorescein Md in an area of the disc Sd/Md is called Fd, the same for a retinal artery is called Fr. Fr was found to be independent of intraocular pressure in the range examined (mean pressures 15--30 mm applanantion). Fd/Fr = omega, the "fluorescein appearance rate" is correlated to the linear velocity of blood in the capillaries of the observed disc area and hence to its circulation. omega was found to be diminished in 6 out of 9 cases with ocular tension between 26 and 38 mm applanation, but not in 3 cases. It was not diminished in 4 cases with 22-25 mm applanation. Further studies are necessary to elucidate these findings suggesting some adaptation of disc circulation to intraocular pressure but not proving it: fluorescence from vessels behind the lamina cribrosa has the tendency to seemingly "normalise" omega.

Adult↗

PubMed1975