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Biomedical subjects

H Gartmann

Publications and source records attributed to H Gartmann.

At least 19 recordsLinked to original sources
PubMed1990

[Proliferative myositis].

We report on a 42-year-old woman showing a rapidly growing tumor on her left flank; it was removed by surgery. Histological examination revealed the typical picture of proliferative myositis. Since the clinical symptoms of this disease are nonspecific, the diagnosis always depends on histological evidence. Despite its rapid growth and its cellular pleomorphism, proliferative myositis is a reactive process and has to be differentiated histologically from sarcoma of the soft tissue.

Adipose Tissue↗
PubMed1990

[Degenerative changes in schwannoma (neurilemmoma)].

We report on a 51-year-old male patient showing a slowly growing, pedunculated, hairless tumor on the back of his head. The tumor grew up to the size of 4.2 cm in diameter, before it was removed by surgery. Histological examination revealed the typical picture of an ancient schwannoma (degenerated neurilemmoma). In spite of its highly atypical nuclei, the biological behavior of ancient schwannoma is benign, and it must be differentiated from malignant tumors of the nerve sheath.

Connective Tissue↗
PubMed1988

[Elastofibroma dorsi].

We report on an 80-years-old woman suffering from subacute prurigo simplex, who had developed a painless subcutaneous tumor on her right upper back, 8 cm in diameter. In palpation, the tumor was firm and did not adhere to the overlying skin. The movability of her arms and back was not restricted. The tumor could not be distinguished from its surrounding tissue by means of ultrasound. Surgery revealed that the tumor was firmly attached to the thoracic fasciae, periosteum, and ligaments, which prevented its complete removal. On histological examination, the tumor was diagnosed as elastofibroma dorsi. We discuss our microscopical findings of this very rare neoplasm in detail.

Aged↗
PubMed1988

[Vater-Pacini neurofibroma].

We report on a 49-year-old female patient suffering from Pacinian neurofibroma on her right middle finger. The microscopical findings of this rare neoplasm are discussed in detail.

Female↗
PubMed1988

Architectural features in melanocytic lesions with cellular atypia.

According to the quantity of single atypical melanocytes at the dermoepidermal junction 334 nevi were assigned to 3 groups: (1) with pronounced nuclear and cellular atypia (n = 73); (2) with moderate atypia (n = 127), and (3) without atypical melanocytes (n = 134). Three architectural features were almost exclusively observed in groups 1 and 2 with cellular and nuclear atypia: atypical localization of melanocytes in the epidermis, irregular distribution of melanocytes in the junctional zone and atypical nests of melanocytes. A combination of 2 or 3 of these features was seen in 76% of the nevi with pronounced cellular and nuclear atypia, in 28% of those with moderate atypia and in none of those without atypical melanocytes. Regarding 4 other criteria only minor but still statistically significant differences were found between the 3 groups of nevi. We conclude that these 4 other criteria, i.e. inflammatory infiltrate, lamellar and/or concentric fibroplasia, persisting lentiginous hyperplasia and dust-like pigment in melanocytes and nevus cells are not helpful for the diagnosis of a dysplastic nevus because of their low specificity. Minimal requirements for the diagnosis of a dysplastic nevus are suggested.

Adolescent↗
PubMed1988

Malignant blue nevus with metastases to the lung.

A malignant blue nevus of the right upper arm with hematogeneous lung metastases is presented. Histological examination showed that the tumor was composed of spindle, dendritic, and globular cells with hyperchromatic and polymorphic nuclei, atypical mitoses, and tumor cell necrosis. There was no proliferation of atypical melanocytes at the dermoepidermal junction. Histologically, malignant blue nevus should be distinguished from benign cellular blue nevus, primary cutaneous malignant melanoma, cutaneous metastases of malignant melanoma, and clear cell sarcoma.

Adult↗
PubMed1985

[Eccrine porocarcinoma].

We report on a 74-year-old female suffering from an eccrine porocarcinoma nea the mons pubis. Two additional tumors appeared in the same area. The three tumors revealed different stages of development.

Adenoma, Sweat Gland↗
PubMed1985

[Fibrofolliculoma].

We report on a 85-year-old woman suffering from a fibrofolliculoma at the root of her nose. This benign tumor is very uncommon, and its histological findings are little known. Pathogenetically we suspect a self-contained interaction between the epithelial and mesodermal component of the pilary complex.

Aged↗
PubMed1985

Congenital nevi less than or equal to 10 cm as precursors to melanoma. 52 cases, a review, and a new conception.

Fifty-two congenital melanocytic nevi (CMN) as precursors to melanoma or severe melanocytic dysplasia were reviewed macroscopically and microscopically. Forty-eight "small" CMN measured less than 10 cm in diameter. Histologically, only five reached to the lower third of the dermis or subcutis ("deep type"); the remaining 47 were limited to the upper two thirds of the corium ("superficial type"). There were 47 invasive melanomas, two in situ melanomas, and three severe focal melanocytic dysplasias. All melanomas were of "epidermal" origin and primarily of the superficial spreading type. The age at diagnosis ranged from 18 to 79 years. Prepubertal melanomas were not observed. Melanoma may also arise on small CMN. The most frequent origin of the melanomas in small CMN and the preferred age at manifestation seem to be different from that for giant nevi.

Adolescent↗
PubMed1985

[Skin manifestations in sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman syndrome)].

We report on a 19-year-old girl suffering from cutaneous manifestation of sinus histiocytosis associated with massive lymphadenopathy (SHML) (Rosai-Dorfman syndrome); as SHML had first appeared at her 7th month of life, the disease had taken an uncommonly long period of time. At the age of 15, cutaneous manifestations developed on cheeks and left upper arm which histologically showed the same infiltrate as affected lymph nodes usually do in SHML. So far, participation of the cutaneous system in SHML has been observed in only 12 cases.

Adult↗
PubMed1985

[The Spitz nevus. Spindle cell and/or epithelioid cell nevus--a clinical analysis of 652 tumors].

We report on clinical aspects of 652 Spitz' nevi. In 42.9% of the cases, this tumor has been observed in people over 19 years. The female sex with 61.6% was much more concerned than the male sex. Most frequently, the lower extremities were affected (30.1%). The clinical diagnosis of Spitz' nevus could be definitely made in only 13.9% of the cases. We are going to discuss the very variable clinical picture of Spitz' nevus.

Adolescent↗
PubMed1985

[The Spitz nevus. Spindle cell and/or epithelioid cell nevus--a histological analysis of 652 tumors].

652 Spitz' nevi have been histologically analysed and separated into epidermal and dermal changes. There are similarities between Spitz' nevus and melanocytic nevus. 44.9% of the examined Spitz' nevi consist of spindle cells only, 34% of spindle as well as epithelioid cells, and 21% of epithelioid cells only. We are going to discuss the difficulties in histological examination; more or less important signs are differentiated in detail. In some cases, Spitz' nevus will remain a somewhat dubious and disturbing tumor.

Adolescent↗