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Biomedical subjects

H Gallego

Publications and source records attributed to H Gallego.

6 recordsLinked to original sources
PubMed1999

Report of an association between discoid lupus erythematosus and smoking.

Smoking has been shown to be associated with many medical disorders, including many involving the skin. While preliminary studies suggest a modest association between smoking and systemic lupus erythematosus, epidemiologic data on discoid lupus erythematosus (DLE) and smoking are lacking. To study this relationship, we examined current smoking habits in two unique patient populations with DLE. One group was compared with matched dermatology patients while the second group was compared with the corresponding statewide population. For both groups, the current smoking prevalence was much higher than that of the comparison population. For the control-matched group of DLE patients, smoking prevalence was found to be significantly greater than that of controls (odds ratio 12.2; p = 0.001). We therefore propose that smoking is a risk factor for development of DLE.

Adult↗
PubMed1998

Lichen planus and lichen sclerosus overlap.

Lichen planus and lichen sclerosus share several common features, including lymphocytic infiltration at the dermal-epidermal junction, clinical involvement of both skin and mucosa, erosive disease of mucosal surfaces, and the occasional occurrence of squamous cell carcinoma at the site of chronic, erosive mucosal lesions. In spite of these similarities, there are remarkably few reports of patients who concurrently have evidence of both diseases. We report a patient who had oral lesions of lichen planus and penile lesions of lichen sclerosus and we review possible mechanisms to explain this association.

Aged↗