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Biomedical subjects

H Gage

Publications and source records attributed to H Gage.

8 recordsLinked to original sources

Explaining breast cancer mortality in England: the effect of socioeconomic factors and health care services.

England has the worst mortality rate for breast cancer in the developed world. Using area-level data for 145 health districts in England, this study seeks to explain variations in breast cancer mortality among women aged 50-64 years in the period before the National Breast Screening Programme became operational. It is found that socioeconomic and behavioural factors had a larger effect on mortality than did health care inputs. This might be explained both by inadequacies in the data, and by the fact that, in the absence of screening, cancers tend to be detected at a later stage, by which time the chances of a successful outcome are reduced. It is suggested that the impact of health care services in reducing mortality will increase in the future as screening becomes widespread and results in earlier detection and treatment. The prioritization of screening is central to achieving the reductions in mortality from breast cancer specified in the Health of the Nation targets.

Aged

Role of screening in reducing invasive cervical cancer registrations in England.

OBJECTIVE: To estimate the effect of screening on invasive cervical cancer registrations in England. SETTING: The Health of the Nation target for cervical cancer seeks to reduce the incidence of invasive cases (ICD 180) by at least 20% between 1986 and 2000. METHOD: The available area-level statistics on invasive cervical cancer registrations, screening activity, and socioeconomic and behavioural characteristics for 145 district health authorities in England over the period 1985-91 were collected. A multiple regression analysis sought to explain variations in incidence rates by relating screening and socioeconomic and behavioural variables to registration rates. RESULTS: Districts with higher unemployment levels and higher numbers of pregnancies in young women had higher registration rates for invasive cervical cancer. The cervical smear rate for women aged 35-64 in a district was positively related to registrations, whereas the relation was negative for the 20-34 age group. CONCLUSIONS: The higher registration rates for invasive cervical cancer in districts with higher cervical smear rates for women aged 35-64 may reflect historically lower screening cover. The negative relation between the cervical smear rate and invasive cervical cancer registrations in women aged 20-34 is accompanied by high registration rates for preinvasive (CIN III) cervical cancer (ICD 233.1). For the advantages of the Pap test to be fully realised, and for invasive cervical cancer registrations to fall in line with the Health of the Nation targets, a comprehensive screening programme, with a high take up rate is required. The various changes to the screening programme introduced since 1988 should help to achieve this. Public health policy should focus on educating the population about the risk factors for cervical cancer and the significance of screening.

Adolescent

Chronic liver disease associated with high hepatic copper concentration in a dog.

An 8-month-old dog admitted for routine castration was found to have ascites. Liver biopsy revealed inflammation, fibrosis, and a copper concentration of 1,300 ppm on a dry weight basis. As cirrhosis developed, the copper concentration decreased without chelator treatment. At necropsy, the dog had cirrhosis, but the hepatic copper concentration was only 730 ppm.

Animals

Ergonomic principles basic to hand tool design.

A survey of those features of hand tools relevant to the physical interaction between the implement and the human operator. Concepts basics to the optimization of forces are mentioned, followed by a description of some of the more common physiological problems and musculoskeletal complaints associated with improper hand tool and design and usage. An account of the distribution of contact pressures and possible consequences, if these are excessive, is followed by a description of the role of working gloves as related to ergonomic problems and their possible relationships to occupational diseases of the hand and wrist. Some aspects of anatomy and anthropometry pertinent to the optimization of posture, motion patterns and tool size precede a list of desirable features for power tools. A glossary is included as an aid to the reader. The concepts and situations described are applicable to the design and use of the vast majority of hand tools.

Carpal Tunnel Syndrome

Survey of need for industrial hygienists.

Grass roots surveys of the need for industrial hygienists, areas of specialization, and related subjects can fill a real void in currently available information. AIHA local sections and other professional groups may wish to conduct regional studies similar to the one described here. A pooling of results by reporting to their national organizations would be beneficial to all in the profession.

Allied Health Personnel