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Biomedical subjects

H Gänshirt

Publications and source records attributed to H Gänshirt.

At least 19 recordsLinked to original sources
PubMed1987

[Criteria of brain death: 3d generation. Interpretation of criteria established by the Federal Chamber of Physicians in determining brain death].

The criteria of brain death published by the Federal Chamber of Physicians in 1982 in their second generation have stood the test of time and remain valid. The most important amendments in issuing a third generation are the following: In primary cerebral lesions supratentorial lesions have to be distinguished from infratentorial processes. In primarily the infratentorial processes EEG activities of the cortex max outlast apneic brain stem areflexia. Therefore in infratentorial processes controls of the EEG are indispensable. The extinction of evoked potentials, certain conditions being observed, may prove the loss of brain stem function and therefore may allow to shorten observation time, and may offer an alternative to isoelectricity in the EEG or cerebral perfusion stop as a diagnostic procedure. Additional tests for brain death are commented on. Special considerations are necessary in brain death in children.

Brain Damage, Chronic↗
PubMed1985

[Metastases to the nervous system].

Over a period of 13 years, 353 cases of metastases in the brain, spinal canal or peripheral nerves were treated in 14,350 inpatients. In 79.6% of the cases, the metastases were localized intracranially, in 14.7% spinally, in 2.6% peripherally and in 3.1% in several of these sites. Solitary tumors predominated (65.7%). Of 420 intracranial metastases, 336 were located supratentorially (80%) with a slight preponderance on the left side (54.5%), 15% cerebellar, and 5% in the brainstem. Of the spinal metastases, 80% were located in the thoracic spinal cord. Almost 60% of the cases also displayed metastases outside the nervous system, mainly in the skeletal system and the lungs. The most frequent primary tumor was bronchial carcinoma (26,6%) followed by breast cancer (19.5%) and unknown primary tumor (17.6%), which was also not found on autopsy in 0.8%. Rare primary tumors were parotid and pancreatic carcinomas, testicular and bladder tumors. There are correlations between the primary tumor and the location of the metastases in the nervous system in general and in the brain in particular. The latency between diagnosis of the primary tumor and that of the metastasis was 1-3 years. In one out of three cases, the metastasis in the nervous system was the first sign of the tumor condition. In six cases, the metastasis was removed before the primary tumor and two possible kinds of primary tumors were found in seven cases. Compared to intracranial hypertension focal deficit manifestations including focal convulsions occurred twice as frequently in cerebral metastases. Spinal metastases led to CSF blockade in 20%.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed1983

Significance of hemorheology in diagnosis and therapy of ischemic cerebrovascular diseases. Possibilities of therapy: antiedema procedures.

Edema in ischemic cerebrovascular diseases is a cytotoxic edema, followed by a vasogenic edema. An interstitial hydrocephalic cerebral edema is rare. The possibilities of therapy consist in application of osmotherapeutics, diuretics, glucocorticoids, barbiturates and hypothermia. The edema is very much less pronounced in cerebral infarctions than in cerebral hemorrhages or in brain tumors. For this reason, a less-pronounced effect of antiedema therapy is to be expected from the beginning in ischemic cerebrovascular diseases. In addition, practical experience confirms that antiedema treatment is required more rarely and for a shorter time in cerebral infarctions than in cerebral hemorrhages and in cerebral venous thromboses.

Barbiturates↗