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Biomedical subjects

H G Canter

Publications and source records attributed to H G Canter.

10 recordsLinked to original sources

Trigeminal herpes zoster causing mandibular osteonecrosis and spontaneous tooth exfoliation.

We have described a 60-year-old woman with polymyalgia rheumatica treated initially with prednisone but ultimately with azathioprine and cyclophosphamide. Herpes zoster infection along the mandibular division of the right trigeminal nerve ensued with spontaneous exfoliation of two teeth. She subsequently died. Medical practitioners need to be made aware of this rare complication of a common disease.

Azathioprine

Liposomal amphotericin B for treatment of pulmonary aspergillosis in a heart transplant patient.

Pulmonary aspergillosis developed in a 52-year-old man 2 months after heart transplantation for ischemic cardiomyopathy. Conventional amphotericin B therapy caused marked deterioration of his already compromised kidney function after only 10% of the projected total dose. Conversion to liposomal encapsulated amphotericin B was associated with reversal of the kidney dysfunction and clearing of the pulmonary infiltrate. It is now 16 months since completion of therapy, and there is no evidence of recurrent infection.

Amphotericin B