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Biomedical subjects

H G Borst

Publications and source records attributed to H G Borst.

At least 253 records · Page 14Linked to original sources
PubMed1976

[Studies on the local motility and blood circulation of the heart muscle during and after long-term coronary strangulation].

In ten young pigs a severe prolonged and critical stenosis of a major coronary artery was produced under control of an electromagnetic flowmeter. With stepwise constriction flow could be reduced to 55% of control with only minor hemodynamic changes. Local myocardial segment shortening was depressed to approximately 30% of control values. Hypokinesis was partially reversible within the first 135 min after reperfusion and had disappeared 24 h later. Computerized perfusion scintigraphy with radioactive microspheres gives a reliable approximation of the degree of myocardial blood flow reduction.

Animals↗
PubMed1976

[Frequency-optimal pacing in chronic pacemaker therapy].

Hemodynamic studies were performed in 15 pacemaker patients at rest and during exercise by thermodilution technique and impedance cardiography. Particularly in myocardial failure, individual optimal heart rates were observed, ranging from 90 to 120/min. Mean increase of cardiac output at optimal pacing rate was 1.31/min against stimulation at 70/min. Impedance cardiography showed high correlation to thermodilution technique.

Aged↗
PubMed1976

[X-ray cinematographic studies of local ventricular dynamics after aortocoronary bypass].

In 12 patients with high-grade coronary stenosis local motility before and after aortocoronary vein bypass was estimated by cineradiography of coronary bifurcations and surgically implanted myocardial metal markers. A group of patients with relief of angina showed significant increase of local segment shortening within the first postoperative days. During the following months no further alteration occurred. In three patients with persisting angina no improvement of local motility could be found.

Cineradiography↗
PubMed1975

[Infected groin following vascular surgery].

From August 1972 to July 1973 174 vascular reconstructions in the iliac and femoro-popliteal region were performed. All infections of the groin incision were classified according to Szilagyi. 22% class I and II infections, 2% class III infections were found (3 patients). In two of these patients the bleeding was managed by the following method: The infected piece of the artery was resected. The vascular continuity was reconstructed by autologous vein. The anastomoses were burried in uninfected surrounding muscles. Both patients left the clinic with open leg arteries. Unfortunately we lost the third patient doing an extraanatomical bypass. The reasons for the high incidence of groin infections are discussed.

Arterial Occlusive Diseases↗
PubMed1975

[Solitary pulmonary arteriovenous fistula in infancy and childhood (author's transl)].

Pulmonary arteriovenous fistula is not a rare congenital malformation, but obviously most often it is a very late diagnosis. Moreover the disease is associated with a high risk of serious complications, namely cerebrovascular accidents. Two patients, an one month old infant and an 8 years old boy with typical symptoms and signs are presented. Both of them were operated upon successfully. It is concluded, that the diagnosis of solitary pulmonary arteriovenous fistula should lead to immediate operation, which is technically easy and of low risk only, even in infancy. Conservative surgery is recommended without sacrifice of healthy lung tissue, i.e. local excision or segmental resection in subpleural lesions and lobectomy for deep-seated fistulas.

Adult↗
PubMed1975

[Paraplegia following acute infrarenal aortic occlusion (author's transl)].

The clinical syndrome of paraplegia following acute occlusion of the infrarenal aorta may be caused by either ischemic spinal cord damage or ischemia of the cauda equina and sacral nerve roots and ganglia. The neurologic manifestations are similar and therefore specific anatomic diagnosis is difficult. From October 1972 to February 1975 a total of 31 patients with infrarenal aortic occlusion were treated at the Medizinische Hochschule in Hannover. In nine cases the occlusion up to the renal arteries was acute. Three of these patients presented beside acute ischemic manifestations on both legs and the lower abdominal wall, neurologic symptoms of paraplegia. The anatomic and hemodynamic aspects of ischemic spinal cord damage and those of ischemic lesions of the cauda equina and peripheral nerves are discussed. There appear to be three main mechanisms responsible for vascular paraplegia following acute infrarenal occlusion of the aorta: 1. it may be caused by thrombotic occlusion of a major radicular artery which arises below the level of occlusion. 2. it may be produced by thrombosis of a lumbar collateral acting as major supply to the cord when arteriosclerotic narrowing of the major radicular artery is present. Especially in states of severe hypotension critical interference of blood supply to the spinal cord will result. 3. Paraplegia by ischemia of the cauda and peripheral nervous tissue may also follow prolonged interruption of circulation to this area supplying spinal vessels from low lumbar and sacral arteries.

Aged↗
PubMed1975

[Heart valve surgery in bacterial endocarditis (author's transl)].

Bacterial endocarditis was the cause of heart valve destruction in 23 patients. Additional 5 patients were reoperated because of an infected valve prothesis. 13 were operated upon during the inactive stage. Nevertheless infection recurred after operation at least in one patient. 10 patients underwent operation during the active stage, 6 of these with stable cardiac function, 4 in cardiogenic shock. Hospital mortality was 2/6 and 1/4 respectively. One patient died after three months of persisting infection. Three of five patients with infected valve prosthesis survived reoperation. An attempt is made to define the indication for valve surgery in bacterial endocarditis.

Adolescent↗
PubMed1975

Complications of permanent transvenous cardiac pacing.

Clinical experience with permanent transvenous pacing during a 6 year period at Hannover Medical School is presented. A total of 1,376 pacemaker operations were performed in 799 patients, with a mortality rate of 1.1 per cent. The most common complications were premature battery failure, dislocation of endocardial electrodes, infections of the generator and/or electrodes, and skin ulcerations. In our cumulative follow-up period of 1,225 years, a complication necessitating a reoperation is to be expected after an average function-time of 31 months. Including normal battery exhaustion in this calculation will make reoperation necessary every 21.9 months.

Adult↗