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Biomedical subjects

H Freitag

Publications and source records attributed to H Freitag.

33 records · Page 2Linked to original sources

[Ultrasound misdiagnosis of gallbladder concrements in "phrygian cap" deformity (author's transl)].

Gallbladder septa, for example, in "phrygian cap" deformity, may in rare cases lead to a misdiagnosis of gallbladder stones when B-mode ultrasound with gray scale is used. Among 4,000 upper abdominal ultrasound examinations which included the gallbladder one such case was observed. In view of the frequency of septated gallbladders (about 15%) this, although very rare, cause of false-positive diagnosis of stone should be taken into consideration when interpreting ultrasound tracings.

Cholelithiasis↗

Transport of phosphate analogues in rat-liver mitochondria.

The swelling of rat liver mitochondria has been studied in isotonic ammonium salts of phosphate, thiophosphate, monofluorphosphate, difluorphosphate or in isotonic ammonium malate induced by low concentrations of the mentioned anions. The data lead to the following conclusions. 1. Phosphate, thiophosphate, and monofluorphosphate are taken up by the mitochondria, whereas difluorphosphate is not, indicating that the substrate of the transporter represents the divalent anion HPO24- and not H2PO4-. 2. Thiophosphate, monofluorphosphate and phosphate, but not difluorphosphate induce the swelling of mitochondria in isotonic ammonium malate, only after a lag phase. The length of the lag phase depends on the concentration of inducing anion and pH. This phenomena cannot be explained by the current concept of two independent phosphate-transporting systems in mitochondria.

Animals↗

[The problem of functional achlorhydria].

It was examined whether in anatomically intact specific adenic parenchyma of the gastric mucosa achlorhydria can persist after maximal stimulation or whether there is support to the conception of functional achlorhydria ("functional anacidity") furthermore. Relating to the anatomic structure of the gastric mucosa secretion of chloric acid was studied after submaximal and maximal stimulation in 101 cases. It was shown that there is no correlation between the morphology and the secretion of chloric acid in anatomically intact gastric mucosa after submaximal stimulation. In 18 cases out of 28 only the secretion of acid was in correspondence to the histological condition. In two cases out of 37 with atrophic gastric mucosa diverging results were found. After maximal stimulation with histamine chloride and pentagastrine one out of two cases with histologically intact mucosa showed normochlorhydria after seven days, whereas the second case remained achlorhydric. These results must be interpreted as functional achlorhydria. Submaximal stimulation of gastric secretion as it is practised today does not allow corresponding consequences concerning the morphological condition of the gastric mucosa. Discrepant results are found especially in histologically normal mucosa. There is more congruence in atrophic gastric mucosa.

Achlorhydria↗

[Correlation between prognostically predicted and actually attained refraction].

BACKGROUND: In cataract surgery high quality is demanded. That is why high precision in calculation of IOL power is necessary for predicting postoperative refraction. MATERIALS AND METHODS: In a series of 103 patients the predicted refraction--calculated by the SRK II formula for only one type of IOL (A-constant 118.9)--was compared to the received early and late (3 month) postoperative refraction. RESULTS: The accuracy of IOL calculations in 95% was acceptable--within a range of 2 diopters. The prediction errors of extended values were only shown in cases of axial length of more than 26 millimeters. CONCLUSIONS: The results confirm the fact that by means of SRK II formula the accuracy of IOL calculation is satisfactory in respect of predicted refraction. In eyes of elongated axial length the accuracy is limited.

Adult↗