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Biomedical subjects

H Folgering

Publications and source records attributed to H Folgering.

95 records · Page 6Linked to original sources
PubMedDate not supplied

The diving response depresses ventilation in man.

When the face of diving animals comes into contact with water, the diving response is elicited, resulting in bradycardia, peripheral vasoconstriction and ventilatory depression. The cardiovascular aspects of the diving response have been described in man; little is known about the ventilatory depression in man. Compresses with water of various temperatures were applied to the cheeks of 16 normal volunteers and of two hyperventilating subjects. Ventilation was measured with a spirometer or with a pneumatic thoracic transducer: an accordion shaped balloon, strapped around the thorax. When the ventilation was measured with the spirometer via mouth-piece and nose-clip, the diving response caused ventilatory depressions to 60-70% of control. Water temperatures of 10, 20 and 37 degrees C had no significantly different effects from one another on ventilation. When the face of the subjects was left free of nose-clip and mouth-piece and the ventilation was measured by a thoracic transducer, the diving response caused a ventilatory depression to approximately 60% of control. The ventilatory depression did not adapt within 5 min. The two subjects who hyperventilated reacted qualitatively and quantitatively the same as the other subjects.

Adult↗
PubMedDate not supplied

Primary alveolar hypoventilation (Ondine's curse syndrome) in an infant without external arcuate nucleus. Case report.

A five month old boy suffered from primary alveolar hypoventilation, with attacks of apnea during sleep (Ondine's curse syndrome). The ventilation did not increase when PACO2 was increased. However, it decreased during hyperoxia. This indicates a strong peripheral chemoreceptor drive and a dysfunction of the central chemoreception. The infant died from circulatory failure following an aspiration pneumonia. Autopsy revealed the absence of the external arcuate nucleus, which may be involved in the central chemocreception.

Chemoreceptor Cells↗
PubMedDate not supplied

Control of the end-tidal PCO2 in the hyperventilation syndrome: effects of biofeedback and breathing instructions compared.

Twenty chronic hyperventilation syndrome patients were assigned to biofeedback training to raise end-tidal PCO2 level or received a breathing exercise schedule for home practice. Both methods offered equal opportunity for improving end-tidal PCO2 significantly. Alleviation of complaints, however, was only noticeable in the biofeedback group. This may be due to the fact that improvement in the severity of the hyperventilation syndrome was not only significantly related to increase in end-tidal PCO2 but also to initial end-tidal PCO2 level and state of the ventilatory controlling system. A follow-up evaluation three months after the end of the therapy programs showed an unchanged end-tidal PCO2 level in both groups as compared with post-treatment evaluation, but a significant relapse in complaints in the biofeedback group. Implications of these findings are discussed in the final section of this paper.

Biofeedback, Psychology↗