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Biomedical subjects

H Flaatten

Publications and source records attributed to H Flaatten.

54 records · Page 3Linked to original sources
PubMed1987

Postoperative headache in young patients after spinal anaesthesia.

Spinal anaesthesia was performed on 247 young adult patients with a 25-G needle. Rectal administration of indomethacin had no significant effect on the incidence of postdural puncture headache, which occurred in 16.8% of patients who received the drug compared to 24.5% who received a placebo. A history of headache pre-operatively did not influence the incidence of postlumbar puncture headache.

Adolescent↗
PubMed1987

Central venous catheter with subcutaneous injection port (Port-A-Cath): clinical experience with children.

Long-term intermittent venous access was established in 26 children by means of a central venous catheter (CVC) with a subcutaneous injection port (Port-A-Cath) (PAC). As of December, 1985, PACs had been in place for 20-750 days (cumulative 10,890 days) with 647 entries into the system. The PACs were used for blood sampling and administration of chemotherapy, antibiotics, fluids, total parenteral nutrition (TPN), and blood products. One patient with sever neutropenia (absolute neutrophil granulocyte count [ANC] less than 0.1 x 10(9)/L) at the time of the PAC implant developed an infection around the port after 2 days, with subsequent septicemia (Bacillus cereus) necessitating removal of the PAC. Otherwise, no definite PAC-related infections occurred, including 258 days of neutropenia (ANC less than 0.5 x 10(9)/L). Two PACs were found occluded with greyish deposits of fat and organic material after long-term (45 and 61 days) continuous TPN and were removed. Malposition of catheter, extravasation, thrombosis, and other potential technical or psychological complications were not observed. The children continued normal activities, and the easy venous access decreased emotional stress during treatment. Local doctors were trained to use the PACs, with which they administered maintenance chemotherapy. We conclude that the use of PACs in children is safe, even in the first year of life, and has many advantages when compared with other CVCs currently in use. Strict indications, meticulous implantation technique, and adequate handling are, however, mandatory.

Adolescent↗
PubMed1985

Spinal anaesthesia for outpatient surgery.

In a prospective study of 51 young male outpatients given spinal anaesthesia through a 25-gauge needle, we found a 37.2% incidence of postdural puncture headache. In addition, 54.9% complained of backache after surgery. Occurrence of headache significantly prolonged the sick-leave from work. General anaesthesia would be preferred by 31.4% of patients for a similar procedure in the future. These patients had a higher incidence of postoperative backache and pain during lumbar puncture. It is concluded that spinal anaesthesia is not a satisfactory technique for outpatient procedures in young men.

Adult↗
PubMed1985

Long-term parenteral nutrition using a mixture of fat, amino acids and carbohydrates in a single three-litre bag.

Long-term parenteral nutrition is today an established therapy, both in hospitals and at home. A variety of patients with chronic intestinal dysfunction, leading to malnutrition, are candidates for this treatment. There are however several problems related to this therapy, some of which can be attributed to the infusion system. In Scandinavia most patients receiving parenteral nutrition are given separate bottles of aminoacids, fat-emulsions and carbohydrates. This method has several disadvantages. A new system which includes premixing of all nutrients in a single bag is discussed. Nutrients are mixed in three litre bags in the hospital pharmacy, under optimal conditions, and can be stored refrigerated for several days.

Amino Acids↗
PubMedDate not supplied

Effects of different rinsing regimen on totally implantable vascular access after 70 days infusion of total parenteral nutrition in vitro.

Totally implantable vascular access catheters with injection ports (IP) have been used for total parenteral nutrition (TPN). It is well known that thrombosis may cause occlusion of catheters. Recently we have experienced occlusion of the vascular access chambers in TPN-patients because of precipitation from the solutions. Three different IPs were tested in vitro: Port-A-Cath (PAC), Vascular-Access-Port (VAP), and Implantofix (IMP). Each received a daily infusion of a 2.5-liter solution consisting of fat emulsion, amino acids, glucose, and additives from a "3-liter bag." After infusions, the IPs were washed with three different rinsing methods, one including 45% v/v alcohol. After 70 days the ports were opened and examined for precipitation. Ports washed with alcohol showed no signs of precipitation, while four of six ports which were washed with conventional rinsing methods had precipitates.

Catheters, Indwelling↗
PubMedDate not supplied

Central venous catheter with subcutaneous injection port (Port-A-Cath): 8 years clinical follow up with children.

Long-term intermittent venous access was established in 77 children by means of a central venous catheter (CVC) with a subcutaneous injection port (Port-A-Cath; PAC). Seventy of these children were included in this follow-up study. Sixty-three were treated for different malignant diseases, five for cystic fibrosis, one for severe hemophilia and one for central nervous system disease with seizures as the main problem. As of April, 1992, PACs had been in place for 3/12 to 8 3/12 years (cumulative 175 5/12 years) with 2,206 entries into the system. The PACs were used for blood sampling and administration of chemotherapy, antibiotics, fluids, total parenteral nutrition (TPN) and blood products. Portal infection was observed in four patients of which two patients had their PAC removed. Catheter dislocation was observed in two and catheter breakage in one. Portal occlusion, extravasation, thrombosis leading to removal of the PAC or other technical or psychological complications were not observed. The children continued normal activities, and the easy venous access decreased emotional stress during treatment. Local doctors were trained to use PACs, through which they administered maintenance chemotherapy. We conclude that long-time use of PACs in children is safe and has many advantages compared to traditional CVCs in use. Strict indications, meticulous implantation techniques and adequate handling are, however, mandatory.

Adolescent↗