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H Filipová

Publications and source records attributed to H Filipová.

10 recordsLinked to original sources

[Surgical treatment of liver metastases of non-colorectal tumors].

INTRODUCTION: Surgical resection is the only potentially curative treatment for metastatic cancer to the liver. Therapeutic guidelines for treatment of colorectal liver metastases are well defined, but it remains difficult to establish therapeutic guidelines for heterogeneous group of noncolorectal liver metastases. METHODS: 20 patients with liver metastases of different origin were preoperatively indicated for multimodal therapy and were operated between 1998-2002 at our department. All patients could be divided in 4 homogenous groups according to origin of primary tumour. Group of metastatic Grawitz tumour, breast carcinoma, digestive tumours and a group of different tumours. Preoperative assessing of metastatic extent allowed application of multimodal strategy to each patient. RESULTS: 26 multimodal procedures (6 hemihepatectomies, 6 nonanatomical resections, 4 segmentectomies and bisegmentectomies, 5 implantation of port catheter, 5 cytodestructive procedures) were performed at 20 patients. There were no perioperative death. Postoperative complication was seen in 20% of patients. Actuarial survival rates were 65%, 35% and 15% at 1, 2 and 3 years with median survival 15.6 month. CONCLUSION: Low morbidity and satisfactory survival rates justify a multimodal approach to the surgical management of noncolorectal liver metastases.

Female↗

Liver transplantation in Eastern Europe.

The aim of this report is to evaluate the development of liver transplantation in eastern Europe until mid-1998. Representatives of gastroenterological and hepatological societies of the respective countries answered a questionnaire about the most descriptive items of the issue of liver transplantation. The Baltic countries, together with 6 southern Balkan countries, Moldovia, and Belarus, have not developed a program of liver transplantation. In Ukraine, 7 transplantations were performed, with 3 early deaths. In Russia, 31 liver transplantations were performed, with 8 of the last 12 patients surviving short term. In Slovenia, 1 of 2 patients, and in Yugoslavia, 8 of 9 patients survived. In Croatia and Slovakia, 2 patients each died immediately after surgery. The number of liver transplantations is increasing in both Hungary and Poland. In Hungary, 63 transplantations were performed, with a 1-year survival rate reaching 85%; in Poland, 55 adults and 29 children underwent transplantation, with an actuarial 1-year survival rate of 70%. In former East Germany, 4 centers developed their programs since 1992. A total of 196 transplantations were performed, with 1-year survival rates varying from 80% to 89%. The total spectrum of indications for transplantation was standard, with a greater proportion of hepatocellular cancer compared with Eurotransplant statistics. In the Czech Republic, the first liver transplantation was performed in 1983, but it was not until 1994 that the number of procedures increased steeply. Until mid-1998, a total of 182 transplantations were performed. At the Prague Institute for Clinical and Experimental Medicine, we performed 94 transplantations, with a 1-year patient survival rate of 90.6%. There has been rapid development over the last 3 years in the 3 countries of Central Europe. The progress is influenced by the sweeping political and economic changes.

Adult↗

Qualitative analysis of green coffee by infrared spectrometry.

Principal component analysis and linear discriminant analysis (LDA) were applied to the mid-infrared spectra for the qualitative analysis of the variety of green coffee (Arabica and Robusta). It is shown that the KBr pellet technique in combination with the LDA method can successfully be used for the identification of sample origin.

Journal Article↗