Comment on "The role of laparoscopy in preoperative staging of esophageal cancer".
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Adenocarcinoma↗
Biomedical subjects
H Feussner
Publications and source records attributed to H Feussner.
Quality of life before and after laparoscopic Nissen fundoplication.
BACKGROUND: Gastroesophageal reflux disease (GERD) is a common disorder in the Western world. The acute disease can usually be managed by medical therapy. To prevent relapse, many patients require lifelong medication. In these patients, laparoscopic antireflux surgery offers a good alternative. The aim of this study was to evaluate the postoperative results and compare pre- and postoperative quality of life after laparoscopic Nissen fundoplication. METHODS: Clinical investigations, including esophageal manometry, pH monitoring, and endoscopy, and a previously validated Quality of Life Index, were performed before and a median of 41 month after antireflux surgery in 75 patients. RESULTS: After laparoscopic Nissen fundoplication, the percentage of total time with pH <4 decreased from 10.4% to 3.2% on 24-h pH monitoring. The mean pressure of the lower esophageal sphincter improved from 8.1 to 12.3 mmHg. Esophagitis healed in 63 of 66 patients in whom it was present prior to surgery. The overall Quality of Life Index improved significantly from 86 +/- 16 to 116 +/- 16. CONCLUSION: Laparoscopic fundoplication provides effective and durable relief of reflux in patients with GERD. The Quality of Life Index showed significant improvement after surgery.
Adult↗
[Reduction of surgical access trauma: reliable advantages].
Minimizing the trauma of surgical access is becoming an essential task in modern surgery. The treatment has to become more comfortable for the patient and financial resources have to be considered. Minimally invasive surgery is one of the attempts to achieve this goal. A comparison of surgical procedures, such as cholecystectomy, fundoplication and sigmoid resection in diverticulitis, which are already routinely performed laparoscopically, should be suitable for evaluating whether minor access surgery is really advantageous. The value of minor access may be quantified by different parameters such as influence upon the immunologic function, lung function, postoperative pain, time of hospitalization, return to work and duration of convalescence, as well as a comparison of the effects upon the quality of life index. The data concerning the effects upon immunology are not unequivocal. All in all, the degree of postoperative inflammation seems to be lower after laparoscopic surgery. There is no doubt that there is far less impairment on lung function, the results are better as far as postoperative pain is concerned, and hospitalization and duration of convalescence are shorter. It is also evident that immediately after the operation the quality of life index is superior, which, however, levels out in the course of time. The advantage of minimally invasive surgery is really apparent only after the mastering of the so-called "learning curve" and in cases of benign malignancies. The role of the minor access approach in oncological surgery is, however, not yet defined.
Humans↗
[Endoscopy within the network of diagnostic imaging].
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Diagnostic Imaging↗
Achalasia and esophageal cancer: incidence, prevalence, and prognosis.
Reported incidence rates of carcinoma in patients with achalasia and the prevalence of achalasia in patients with esophageal cancer vary widely in the literature. The prognosis of an "achalasia-carcinoma" is generally considered poor, although systematic studies assessing the incidence, prevalence, and prognosis of patients with "achalasia-carcinoma" are scant. We investigated the incidence of esophageal cancer in a large series of patients with known achalasia, assessed the prevalence of achalasia in patients presenting with esophageal cancer, and evaluated the prognosis of these patients compared to that of patients with esophageal cancer without achalasia. Between 1982 and 1998 a total of 124 patients with primary achalasia were treated and followed at our department. During the same time period 1366 patients presented with esophageal cancer (879 esophageal squamous cell carcinomas, 487 adenocarcinomas). Of the 124 patients with primary achalasia, 4 developed a carcinoma during a mean follow-up of 5.6 years (i.e., an incidence of one carcinoma per 173.6 patient-years of follow-up). Altogether, 13 of 879 patients (1.5%) presenting with esophageal squamous cell carcinoma and 1 of 487 patients (0.2%), presenting with esophageal adenocarcinoma had a history of primary achalasia. Seven patients with achalasia-carcinoma (50%) had early-stage disease (stage I, IIA, or IIB). There was no difference in the prognosis of patients with resected achalasia-carcinoma versus those with esophageal carcinoma but no achalasia. Thus in our population of patients with long-standing achalasia the risk for developing an esophageal cancer was increased about 140-fold over that of the general population. With liberal use of surveillance, carcinoma could often be detected at an early stage in these patients, with a prognosis that was not worse than that of patients with squamous cell esophageal cancer but no achalasia.
Adolescent↗
Three-dimensional navigated laparoscopic ultrasonography: first experiences with a new minimally invasive diagnostic device.
BACKGROUND: A three-dimensional (3D) display of diagnostic imaging methods is technically feasible and increasingly important. However, the technical integration of laparoscopic ultrasound and 3D image reconstruction has not yet been realized. For this purpose, an electromagnetic navigation system was integrated into the tip of a conventional laparoscopic ultrasound probe. This first experience with a certified prototype of a navigated 3D laparoscopic ultrasound probe is reported. METHODS: Navigated 3D laparoscopic ultrasound was compared with the imaging data of 3D-navigated transcutaneous ultrasound and 3D computed tomography (CT) scan. The 3D CT scan served as the "gold standard." Clinical applicability, imaging quality, diagnostic potential, and accuracy in volumetric assessment of various well-defined hepatic lesions were analyzed. RESULTS: Navigated 3D laparoscopic ultrasound facilitates exact definition of tumor location and margins. As compared with the "gold standard" of the 3D CT scan, 3D laparoscopic ultrasound has a mild tendency to underestimate the volume of the region of interest (ROI) (D 3.1%). A comparison of 3D laparoscopy and transcutaneous 3D ultrasonography clearly demonstrated that the former is more accurate for volumetric assessment of the ROI. CONCLUSIONS: Three-dimensional laparoscopic ultrasound imaging with a navigated probe is technically feasible. The technique facilitates detailed ultrasound evaluation of laparoscopic procedures involving visual, in-depth, and volumetric perception of complex liver pathologies. Navigated 3D laparoscopic ultrasound may have the potential to improve the significance of laparoscopic ultrasonography, and additionally to become a valuable technology for planning and improving interventions guided by laparoscopic ultrasound.
Carcinoma, Hepatocellular↗
[Case report: emergency surgery of a giant scrotal hernia].
We present the case of a 61-year-old patient, who had developed a giant scrotal hernia during the course of 30 years. The patient was transferred to our service after stabilization of hemorrhagic shock due to bleeding from varicosis of the giant scrotal sack. The urgent operation was performed by resection of parts of small intestine, colon ascendens, transversum, and the left testis. After 9 days on our intensive care unit and 18 days on our ward the patient was discharged to further ambulatory care. At one year follow up the patient complained about only discrete abdominal problems which could be successfully treated by diet. The operative treatment modalities of so called "giant hernias" as well as possible complication management are discussed.
Aortography↗
[Second opinion in tumor surgery. Valuable--but needing improvement].
In complicated oncological cases, a second opinion is desirable, also in the view of the care-providing surgeon. It serves interdisciplinary therapeutic planning, and helps improve the quality of treatment. In the case of highly consequential interventions, the patient has a legal right to a second opinion. On a practical level, however, the implementation of this possibility encounters problems: organizational shortcomings, incomplete patient documentation, the stresses of patient transportation, loss of valuable time, in particular in the case of postal consultation, following consultation in a center the carrying out of treatment there, whether at the urging of the doctors there or the patient himself, lack of remuneration for the efforts of the consultants. Today, however, all the necessary technical facilities are in place to enable various experts to be consulted, virtually simultaneously, on any case, via video-conferencing.
Germany↗
[Rationale and selection for combined procedures in colonic dysplasias and T1 carcinomas. Laparoscopic-endoscopic local wall excision and segment resection].
Combined endoscopic-laparoscopic procedures may offer an interesting therapeutic option in cases of benign colonic lesions and early T 1 carcinoma where endoluminal resection is not feasible, but oncological resection is not (yet) required. Combined procedures such as the laparoscopically assisted endoscopic resection, the endoscopically assisted laparoscopic wedge or transluminal resection, or the segmental resection can be performed. Experience with this technique is still limited, but has shown that the invasiveness can be reduced by endoscopically guided local excision. If it is possible to keep the incidence of secondary operations low, combined laparoscopic/endoscopic interventions could occupy a valuable place in the therapeutic spectrum.
Adult↗
The relationship between gastroesophageal reflux, intestinal metaplasia and adenocarcinoma of the esophagus.
Currently available data indicate a clear and probably causal relationship between long-lasting gastroesophageal reflux disease, the development of long segments with specialized intestinal metaplasia in the distal esophagus and subsequent progression to adenocarcinoma. To a lesser degree, this also appears to be the case for short segments of specialized intestinal metaplasia in the distal esophagus. In contrast, epidemiological data and classic parameters for the diagnosis of gastroesophageal reflux disease do not currently support a causal role of gastroesophageal reflux in the pathogenesis of specialized intestinal metaplasia at the gastric cardia. Despite its high prevalence and malignant potential, many questions about the prevention and management of intestinal metaplasia in the distal esophagus remain unsolved. In patients with chronic gastroesophageal reflux, current modes of medical therapy do not appear to prevent the development of intestinal metaplasia, while effective anti-reflux surgery seems to have a protective effect. Formal studies with adequate follow-up are, however, still lacking. Neither acid-suppression therapy nor anti-reflux surgery, with or without mucosal ablation, can reliably prevent the malignant degeneration of established intestinal metaplasia of the esophagus. Close endoscopic surveillance with extensive biopsies, therefore, remains mandatory in such patients, irrespective of the treatment modality.
Adenocarcinoma↗
Experimental evaluation of the safety and biocompatibility of a new antireflux prosthesis.
Previous studies have shown that encircling of the esophagogastric junction by a semiabsorbable scarf effectively prevents gastroesophageal reflux. The present study was performed to assess the long-term safety and biocompatibility of this type of scarf. The semiabsorbable scarf was implanted into 20 dogs either laparoscopically or via laparotomy. Pre- and post-operatively, contrast radiography, esophageal manometry, and upper gastrointestinal endoscopy were performed. No cases of perforation, stricture formation or other adverse effects were found after 1 and 2 years. It is concluded that the new type of scarf is without any adverse side-effects. Functional evaluation in reflux patients appears to be warranted.
Animals↗
[Guidelines by the German Society of Digestive and Metabolic Diseases for treatment of gallstones. German Society of Digestive and Metabolic Diseases].
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Cholecystectomy↗
International Workshop on the clinical impact of endoscopic ultrasound in gastroenterology.
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Endoscopy, Gastrointestinal↗
Laparoscopic cardiomyotomy in the treatment of esophageal achalasia.
Tu evaluate the usefulness of the laparoscopic approach as the standard procedure in the surgical treatment of achalasia. Among different competing options of the treatment of esophageal achalasia, extramucosal myotomy of the lower esophageal sphincter--usually combined with anterior fundoplasty--is the most effective but also the most invasive approach. Minimally invasive performance of this operation reduces invasivity and should make the operative treatment a more attractive alternative to other procedures, such as pneumatic dilatation or botox injection. From 1991 till 1997, 27 patients underwent laparoscopic Heller Dor operation (16 males, 11 females, mean age 37 years). Diagnosis was established in all of them by an esophagogram and esophageal manometry. The main symptom was dysphagia in all of the patients. No mortality was observed in this series. There were no conversions to laparotomy. The single intraoperative complication was one case of iatrogenic mucosal laceration. Post operative complications were found in one case of wound infection, and two cases of pneumomedistinum. After a mean follow-up of 33 months (3-77), all patients are without dysphagia and without pathological gastroesophageal reflux. The mean value of residual LES pressure could be reduced from 21 +/- 6.4 mmHg to 7.44 +/- 2.7 mmHg. Laparoscopic cardiomyotomy is at lesat as safe, in terms of morbidity and mortality, as open surgery and similarily effective in alleviating dysphagia. Short hospitalisation and convalascent periods have provided an attractive alternative to repeated dilations for many patients.
Adolescent↗
[Traditional extraluminal operation for Zenker's diverticulum].
The classical surgical approach for the treatment of Zenker's diverticulum consists of diverticulectomy and cervical myotomy. In very small diverticula myotomy alone is sufficient. The complication rate of the procedure is tolerable. Long-term functional results are good in as much 90% and more. Despite the increasing importance of alternative approaches, the conventional extraluminal surgical operation for Zenker's diverticulum will remain the treatment of choice in stage I-III cases.
Endoscopy↗
[Modern diagnostic workup of blunt abdominal trauma].
Lethality and morbidity of blunt abdominal trauma are directly dependent on the immediately valid diagnostic work-up. Since blunt abdominal trauma usually occurs in the setting of multisystem injury and patients are no longer cooperative, clinical methods of diagnosis are unreliable. In regard to the imaging procedures, the practical approach has been simplified and standardized in the last few years. Initially, ultrasonography of the abdomen is performed. If the patient is hemodynamically unstable because of intra-abdominal loss of blood, this can be reliably detected by ultrasound and emergency laparotomy is indicated. If patients are hemodynamically stable, more sophisticated assessment of the abdomen can be achieved by computed tomography. The next step depends on direct or indirect signs of an intra-abdominal lesion. Angiography may be indicated in injuries to the liver, spleen, kidney, mesenteric root or caval vein. If lesions to the liver, biliary or pancreas are detected, ERCP may be required. Lacerations of hollow organs are identified by fine-needle aspiration of free intra-abdominal fluid. Findings on computed tomography are usually reliable enough to support a more conservative approach in the treatment of parenchymal lesions in blunt abdominal trauma. Since the facilities to perform ultrasound are provided in all emergency units and knowledge of ultrasonography is an essential part of surgical training, competitive diagnostic procedures like peritoneal lavage have completely lost their former important clinical role. Similarly, diagnostic laparoscopy is - in contrast to abdominal perforations - no longer of importance.
Abdominal Injuries↗
Endoscopic stapling diverticulostomy for Zenker's diverticulum.
Endoscopic stapling diverticulostomy (ESD) using an endostapler is a modification of the standard endoscopic treatment of Zenker's diverticulum (ZD). It is characterized by complete myotomy of the upper esophageal sphincter, with division of the common wall between diverticulum and esophagus, followed by immediate simultaneous closure of the divided edges with the staples. ESD was performed on 21 patients with ZD between January 1996 and October 1997. The results were then evaluated. Operation time averaged 22 min. Wide opening of the diverticulum and excellent hemostasis were achieved. All of the patients but one, who died postoperatively of myocardial infarction, resumed oral intake without any evidence of cervical sepsis or mediastinitis. Complete relief of dysphagia was achieved in all 20 patients. Hospital stay averaged 4.7 days (range, 2-7 days). The patients were followed up after ESD for a median time period of 12 months. No relapses were recorded. ESD is an effective endoscopic treatment for ZD that entails a low risk of complications and requires only a short period of hospitalization.
Adult↗
Self-guided robotic camera control for laparoscopic surgery compared with human camera control.
BACKGROUND: In laparoscopic surgery, the surgeon no longer has direct visual control of the operation area, and a camera assistant who maneuvers the laparoscope is essential. Problems of cooperation between the two naturally arise, and a robotic assistant that automatically controls the laparoscope can offer a highly desirable alternative to this situation. METHODS: A self-guided robotic camera control system (SGRCCS) based upon a color tracking method has been developed and its use evaluated in 20 cases of laparoscopic cholecystectomy and compared with using human camera control. RESULTS: In 83% of the patients the procedures were successfully completed with the SGRCCS. Set-up time for the robot averaged 21 minutes; and the surgical time with and without the robot averaged 54 and 60 minutes, respectively. Using the robot instead of a human camera assistant significantly reduced both the frequency of the camera correction, 2.2 per hour compared with 15.3 per hour, and frequency of the lens cleaning, 1.0 per hour compared with 6.8 per hour. Subjective assessment by the surgeon revealed that the robot performed better than the human assistant in 71 % of the cases. CONCLUSIONS: In laparoscopic surgery, the SGRCCS offered optimal camera guidance and helped to maintain the surgeon's concentration during the operation.
Cholecystectomy, Laparoscopic↗