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Biomedical subjects

H Feigenbaum

Publications and source records attributed to H Feigenbaum.

225 records · Page 13Linked to original sources
PubMedDate not supplied

Comparison of echocardiography at peak exercise and after bicycle exercise in evaluation of patients with known or suspected coronary artery disease.

To determine if echocardiography done immediately after bicycle exercise provides the same information as imaging at peak exercise, we evaluated 104 consecutive patients being studied for coronary artery disease. Interpretable exercise echocardiograms were obtained in 96 patients (92%), 29 of whom had a new wall motion abnormality detected with exercise echocardiography. Of these 29 patients, 10 had a wall motion abnormality detected in apical views obtained during peak exercise that resolved by the time apical imaging was performed after exercise. Three of these 10 patients, however, had wall motion abnormalities in parasternal views taken after exercise in areas adjacent to the wall motion abnormality imaged at peak exercise. The sensitivity of exercise-induced wall motion abnormality for the detection of significant coronary artery disease in those patients undergoing coronary arteriography was 70% for imaging done after exercise versus 100% for imaging done at peak exercise. Six patients' conditions would have been misclassified as normal if only imaging done after exercise had been performed. We conclude that the addition of echocardiographic imaging at peak exercise on a bicycle enhances the sensitivity for the detection of coronary artery disease with exercise echocardiography.

Adult↗
PubMedDate not supplied

Comparison of regional and global left ventricular function by serial echocardiograms after reperfusion in acute myocardial infarction.

Fifty patients undergoing successful reperfusion therapy (percutaneous transluminal coronary angioplasty 20, thrombolysis 10, combined 20) for acute myocardial infarction were evaluated with serial two-dimensional echocardiograms performed early (less than 24 hours, mean 8 hours) and late (greater than 3 days, mean 6 days) after presentation. Treatment occurred within 12 hours of the onset of symptoms with most patients achieving reperfusion in less than 6 hours (mean 4.7 hours) from the onset of pain. Reperfusion was demonstrated short-term by angiography in 42 of 50 patients (84%). Four patients had clinical signs of reperfusion and subsequent angiographic confirmation. An additional four patients with "stuttering" infarct courses were treated late by percutaneous transluminal coronary angioplasty. Echocardiograms were analyzed for global performance by calculation of fractional area change at the papillary muscle level and ejection fraction (biplane Simpson's rule) in 18 patients in whom this analysis could be performed. Measurements of regional function included fractional shortening at the base (n = 37), regional wall motion index (n = 50) and percent of normal functioning myocardium (n = 50). Overall there was a significant improvement in regional wall scores and percent of functioning myocardium (regional wall motion index 1.73 to 1.43, p less than 0.001 and percent of functioning myocardium 0.61 to 0.70, p less than 0.001) but only a trend toward improvement when global function was assessed by ejection fraction (0.42 to 0.48, p less than 0.14).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMedDate not supplied

Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms.

We have presented recommendations for the optimum acquisition of quantitative two-dimensional data in the current echocardiographic environment. It is likely that advances in imaging may enhance or supplement these approaches. For example, three-dimensional reconstruction methods may greatly augment the accuracy of volume determination if they become more efficient. The development of three-dimensional methods will depend in turn on vastly improved transthoracic resolution similar to that now obtainable by transesophageal echocardiography. Better resolution will also make the use of more direct methods of measuring myocardial mass practical. For example, if the epicardium were well resolved in the long-axis apical views, the myocardial shell volume could be measured directly by the biplane method of discs rather than extrapolating myocardial thickness from a single short-axis view. At present, it is our opinion that current technology justifies the clinical use of the quantitative two-dimensional methods described in this article. When technically feasible, and if resources permit, we recommend the routine reporting of left ventricular ejection fraction, diastolic volume, mass, and wall motion score.

Algorithms↗
PubMedDate not supplied

Regional wall motion index for infarct and noninfarct regions after reperfusion in acute myocardial infarction: comparison with global wall motion index.

A regional wall motion index has been derived from two-dimensional echocardiograms by use of a 16-segment model that was subdivided into anterior (nine segments) and infero-postero-lateral (seven segments) regions. This new method is compared with the use of a previously described global wall motion index for the analysis of serial echocardiograms after reperfusion in 23 patients who had acute myocardial infarction. Mean global index improved from 1.84 +/- 0.46 to 1.56 +/- 0.37 at 24 hours (p less than 0.01) and to 1.50 +/- 0.29 after 3 days to 7 days (p less than 0.02), whereas mean regional index for infarct regions improved from 2.28 +/- 0.73 to 1.82 +/- 0.58 at 24 hours (p less than 0.01) and to 1.70 +/- 0.42 after 3 to 7 days (p less than 0.01), with no significant change in the noninfarct index (1.34 +/- 0.32 initially and 1.28 +/- 0.36 after 3 to 7 days). Although both global and regional indexes effectively demonstrate early recovery of left ventricular function, (within 24 hours in many patients), the regional index for infarct regions is higher than the global index and effectively distinguishes between infarct and noninfarct segments. An overlap index in which an additional apical segment is included in the anterior region (10 segments) for anterior infarctions and in the infero-postero-lateral region (eight segments) for inferior infarctions results in a greater differentiation between infarct and noninfarct regions, with the mean initial noninfarct overlap index (1.17 +/- 0.33) significantly less than the nonoverlap index.(ABSTRACT TRUNCATED AT 250 WORDS)

Echocardiography↗
PubMedDate not supplied

Transthoracic ultrasonic visualization of coronary atherosclerosis.

Although transthoracic ultrasonic visualization of the coronary arteries is technically demanding, many groups of investigators have demonstrated the feasibility of recording the proximal coronary arteries. Technical advances such as the introduction of anular array transducers and digital recording techniques have improved the prospect of obtaining this examination in a reasonable number of patients. It is now possible to detect atherosclerotic disease in the left main and the proximal left anterior descending coronary artery in 70% to 80% of all patients. This echocardiographic technique appears to be a sensitive means of detecting coronary atherosclerosis. Preliminary data suggest that this examination may be helpful in making the differential diagnosis of ischemic cardiomyopathy and idiopathic dilated cardiomyopathy.

Coronary Artery Disease↗
PubMedDate not supplied

Comparison of digital with videotape echocardiography in patients with chest pain in the emergency department.

We prospectively compared digital echocardiographic images, by a minimal digital-acquisition strategy, with videotape images to determine the diagnostic utility of digital imaging in patients admitted to the emergency department with chest pain. Digital acquisition has many potential advantages for evaluating echocardiographic images, especially in the acute-care setting. It is not yet known how much the imaging study can be condensed with digital technology and still provide the necessary information needed for clinical echocardiographic diagnosis. One hundred seventeen patients with diagnoses consisting of coronary artery disease, pericardial disease, and valvular disease were studied. Overall agreement between videotape and digital recordings with regard to normal versus abnormal wall motion was 94% (p < 0.001). The wall motion score index, a semiquantitative measure of global function, also correlated well (r = 0.94). Complete concordance was noted in all patients with aortic stenosis and pericardial effusion. Digital echocardiographic imaging, by a minimal-acquisition strategy, is an accurate summary of the complete echocardiographic examination and provides the relevant diagnostic data needed for the assessment of patients with chest pain in the emergency department.

Chest Pain↗
PubMedDate not supplied

A systematic approach to echocardiographic image acquisition and three-dimensional reconstruction with a subxiphoid rotational scan.

Rotational scanning from the subxiphoid position is an image acquisition technique used for reconstruction of dynamic three-dimensional echocardiographic images in infants and small children. The orientation of the heart within the three-dimensional data set is variable and dependent on the image plane at which rotational scanning was initiated. We describe an image acquisition technique that standardizes the orientation of the heart within the three-dimensional data set, thereby permitting a systematic approach to the reconstruction of three-dimensional renderings. Thirteen infants and small children with congenital heart disease were studied by this approach. Illustrative examples are provided. The average time required to derive a three-dimensional rendering was 37 +/- 9 minutes. We conclude that subxiphoid rotational scanning by a systematic approach to image acquisition and reconstruction can be applied successfully to the derivation of three-dimensional renderings of congenital cardiac defects.

Child↗