The founding of the First University Eye Clinic in Vienna.
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Biomedical subjects
Publications and source records attributed to H Fanta.
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Eduard Zirm (1863-1944) was the first ophthalmologist to perform a successful keratoplasty, in 1905. He submitted his report on the operation for publication in the "Graefe Archiv für Ophthalmologie" on July 9, 1906. The report appeared that same year. A brief historical survey is given here.
The clinical efficacy of Efemoline eyedrops [fluourometholone (0.1%) + tetryzoline (0.25%)] and of fluorometholone 0.1% was investigated in a double-blind controlled clinical trial in 35 patients (63 eyes) in treatment of the upper bulbus area and postoperatively after surgery for cataract, glaucoma and strabismus. Both drugs were effective inflammation inhibitors. The superiority of fluorometholone + tetryzoline over fluorometholone was evident: subjective symptoms improved much more quickly. No tendency toward elevation of intraocular pressure was found. The combined preparation was compatible and produced no side-effects.
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Cataract extraction after a fistulizing operation poses many problems for the surgeon. No satisfactory solution has been found yet to these problems, although the procedure has become safer owing to new microsurgery techniques, so that the rate of success is higher than with previous techniques.
After a classification in benign and malignant tumours and in pigmented and non-pigmented growth, attention is drawn to the fact that most of the tumours lie in the palpebral fissure and are benign. Leukoplakia is a clinical description but not a diagnosis. Both the benign and the malignant growths can be called Leukoplakia. The intra-epithelial epithelioma is often incorrectly diagnosed as Bowen's disease. This disease of the skin and the intraepithelial epithelioma of the limbus are histologically quite different, and therefore the term Bowen's disease is incorrect. Not all the various tumours occur with the same incidence, e. g. the squamous cell carcinoma occurs more often in some countries than in others. The malignant melanomas of the conjunctiva are not so malignant as in the caruncle or cornea. In the conjunctiva secundary melanomas can occur after penetration of an intraocular melanoma through the sclera; similary metastases can occur in the form of epibulbar tumours. In all cases the epibulbar tumour should be excised very carefully and a histological examination is necessary for the diagnosis.
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A brief description is given of a congenital bone formation in the orbit lying on the surface of the outer canthus of the left eye, without any connection to the bulb.
A report is given on a method for cataract extraction after fistulizing operation. The incision is made in a straight line on the cornea underneath the fistula, so that the two ends of the incision are in the limbal region. This corneo-limbla incision does not injure the fistula. The closure is performed under the microscope with a continuous suture. The results obtained support the security of this method.
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A report is given on the inheritance of congenital cataract in two families. While in one family the males were mainly affected, in the second faimily the females were mainly affected with congenital cataract. In our experience an operation is only indicated if the visual acuity is no longer sufficient for day-to day living (less than 0.25).
From pertinent cases a contribution to the pathology of melanoma is published here. The histological structure of melanoma in the various eye tissues is dependent on the properties of the tissue in which the melanoma grows. By means of an example we have tried to throw light on the question of the differential diagnosis between a primary tumor and a metastatic deposit, although a single case cannot be used as proof. An intraocular degenerate melanoma and a melanomametastasis in the conjunctiva after a skin tumor are also demonstrated.
A report is given on transpupillar vitrectomy with the suction wedge for prolapse of the vitreous after intracapsular cataract extraction. From the results obtained this method can be recommended. In aphakic eyes with drawn up pupil the pupil should be cut out underneath after opening the anterior chamber. Also in this case vitrectomy must be performed before closure of the anterior chamber.
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