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Biomedical subjects

H F Hoitsma

Publications and source records attributed to H F Hoitsma.

At least 19 recordsLinked to original sources

[Nonspecific symptoms due to gastrointestinal stromal tumors].

Three patients, two women aged 64 and 52 years and one man aged 78 years, had non-specific symptoms and they had signs of a tumour at imaging examination. Immunohistochemical study of operation preparations led to the diagnosis of 'gastrointestinal stromal tumour' (GIST). It is important to consider the possibility of a GIST at surgery, because the potential malignancy requires a resection with free margins.

Aged

[Prospective follow-up of patients with abdominal symptoms treated by emergency room physicians].

In order to evaluate the functioning of emergency room (ER) physicians, patients seen at the ER of the Onze Lieve Vrouwe Gasthuis. Amsterdam, the Netherlands, for abdominal symptoms without having been referred by the GP, were questioned by letter about the course of events two weeks after their visit. Of the 1853 patients with abdominal symptoms attending the ER in July-December 1997, 1221 had no referral letter; of these, 933 were treated independently by the ER physician. Of the latter, 814 were sent a letter, to which 663 of them responded. 307 of them had visited the GP and 48 an ER. Of these 48 patients, 17 had been admitted and 14 of them had been operated. In seven of the 17 patients, the condition had not been recognized by the ER physician at the first visit.

Abdominal Pain

[Good results from treatment of patients with abdominal pain at the emergency department of the Amsterdam OLVG Hospital].

OBJECTIVE: Evaluation of the treatment of patients with abdominal complaints at the first aid department of a city hospital, where patients were treated by emergency doctors (EMD) in combination with specialists. DESIGN: Retrospective, descriptive. SETTING: Onze Lieve Vrouwe Gasthuis, first aid department, Amsterdam, the Netherlands. PATIENTS AND METHOD: Data were collected on diagnosis, treatment and course in 3235 patients with abdominal complaints seen at the first aid department in 1997. Non-referred patients were treated by EMD who if necessary consulted a specialist. Referred patients were seen by specialists. RESULTS: Of the 2931 patients who visited the first aid department once, 1975 patients (67%) were seen after self-referral. Of this group, 1557 patients (79%) were treated by the EMD alone and could be sent to the general practitioner (GP) without consulting a specialist. These accounted for 53% of the 2931 patients with abdominal complaints. The EMD used fewer additional tests than the specialist. Of the patients, 91% could be treated conservatively, only 9% were operated. Fifty-three patients died. Analysis of the group of 304 patients who visited the first aid department more than once in the year of study, showed that in 28 cases the diagnosis was missed (in 17 cases by the EMD and in 11 by the specialist). Of this group 23 had to be operated upon. CONCLUSION: The organisation of a first aid department like that in the OLVG, with EMDs and specialists, appeared efficient; the rates of morbidity, mortality and missed diagnoses are acceptable. With relatively few additional tests, the EMD appeared to be able to differentiate between GP care and hospital care.

Abdominal Pain

[More recurrencies than expected following inguinal hernia surgery].

OBJECTIVE: To make an inventory of inguinal hernia repairs performed in one year, and to analyse the number of and origin of recurrent hernias. DESIGN: Retrospective. SETTING: Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands. METHOD: Analysis of all hernia operations performed in Amsterdam and Amstelveen in 1994 in male patients over 18 years of age. Request of national data, computer data from the hospitals, hand count of all operation reports and investigation of patient files. RESULTS: In 1994, 1108 patients were operated for inguinal hernia on one or two sides. In 216/1108 (19.5%) cases recurrent hernia was involved. According to national statistics this occurred in 175/1123 (15.6%). In the two University hospitals 25.7% of all repairs were for a recurrent hernia, in the two hospitals with a surgical training programme this proportion was 17.9% and in the five hospitals without a training programme it was 18.6%. Of the early recurrences (within two years) 82.5% (47/57) were reoperated in the same hospital as before but of the late recurrences (more than 10 years) this proportion was only 26.8%. Only 16.6% (36/216) of the patients with a recurrence were reoperated by the same surgeon who had performed the prior operation. Most popular method for repair was a Bassini (59%). In the training hospitals more early recurrences were repaired than in the non-training hospitals. CONCLUSION: The percentage of hernia repairs for recurrent hernia is higher than national statistics suggest and higher than expected. Surgeons have little insight into their performance as many recurrences are repaired by another surgeon and many recurrences occur after ten years. Better training and more use of modern techniques may improve results.

Academic Medical Centers

[Continent ileostomy following discontinuation of ileoanal anastomosis with ileum reservoir; good results in 7 patients].

OBJECTIVE: To study the results of constructing a continent ileostomy in cases of problems with a former ileoanal pouch operation. DESIGN: Retrospective and questionnaire study. SETTING: Onze Lieve Vrouwe Gasthuis, department of General Surgery, Amsterdam, the Netherlands. METHOD: The operations of 7 patients in the period 1988 to 1993 were analysed for indication and postoperative results; the long term functioning was determined by means of a questionnaire. Indications for removal of the ileoanal pouch were septic problems in the true pelvis, untreatable inflammation of the pouch with high defecation frequency and incontinence. RESULTS: The results in all 7 patients were good. No postoperative complications were observed. However, supra-anal sinus problems developed in the next 2 years in 6 out of the 7 patients and in 4 had to be treated by operation. The follow-up after 5 years on average showed that functioning was good in all patients. Because the continent ileostomy gave minimal trouble in work, sport and social life, the patients' satisfaction was high. CONCLUSION: The continent ileostomy should be considered a good alternative to a terminal ileostomy, notably for patients in whom resection of a dysfunctioning ileoanal pouch will be performed. Continence can be preserved in this way, which is of great importance to the patient.

Adult

Role of the Shouldice technique in inguinal hernia repair: a systematic review of controlled trials and a meta-analysis.

The Shouldice technique for inguinal hernia repair has been suggested by some authors as the best conventional method against which other methods using prostheses should be compared. The paper which follows is a systematic review involving a comprehensive search of the medical literature to identify all clinical trials (article or abstract) evaluating the Shouldice repair. After assessment of certain quality criteria, the best studies were pooled in a meta-analysis. Nine publications were found with 11 study arms. In ten studies the results of the Shouldice technique were better than the results of the control arm. Six studies could be pooled in a meta-analysis of 2500 patients; Shouldice was significantly better than control methods (relative risk 0.62 (95 per cent confidence interval 0.45-0.85)). In spite of possible bias caused by different variables (modifications in operative technique, suture material, level of surgeon, follow-up methods and outcome measurement), the results of this systematic review suggest that the Shouldice method is the best current conventional technique for inguinal hernia repair.

Controlled Clinical Trials as Topic

Transphrenic dissemination of actinomycosis.

Thoracic actinomycosis is an uncommon disease and often presents difficulty in diagnosis. Two cases are presented in which thoracic actinomycosis produced fistulae between the thoracic and abdominal cavities. Surgical drainage and high dose penicillin for at least 4-6 months was the treatment of choice.

Actinomycosis

Primary inguinal hernia repair in The Netherlands.

OBJECTIVE: To assess the operative methods used in Dutch surgical practice to repair the inguinal floor of the primary hernia. DESIGN: Survey by questionnaire. SETTING: University department of Surgery, The Netherlands. SUBJECTS: All Dutch Surgeons. OUTCOME MEASURES: Answers to questions about the methods of repair used, specific surgical options, and materials. Comparison of training hospitals and district hospitals. RESULTS: Replies were received from 145/155 departments (94%), but from only 448/774 individual surgeons (58%). 192 (43%) used one method alone (Bassini 71, Shouldice 49, McVay 36, Griffith 24 and others 12) and 256 (57%) of surgeons used combinations of 11 different methods. Only 9 used a prosthetic mesh and 7 laparoscopic repair. The Shouldice method was significantly more popular in training hospitals compared with non-training hospitals (36%) (71/199) compared with (20%) (48/249) (p < 0.05). There were many modifications to accepted methods. Only 78% (94/121) of surgeons who said that they did a standard shouldice repair incised the transversalis fascia. 64% (287) of surgeons said that they modified their technique to suit individual patients. CONCLUSION: In the Netherlands there is no standard technique of inguinal hernia repair.

Hernia, Inguinal

[Leiomyosarcoma of the small intestine: a rare cause of gastrointestinal blood loss].

A 61-year old man is described with recurrent gastrointestinal bleeding, due to a metastatic jejunal leiomyosarcoma. Because of the low incidence and the aspecific symptoms, a long delay occurred until the bleeding tumour and its metastases were demonstrated at radionuclide scanning and mesenteric angiography. The tumour-bearing segment could be removed by simple surgical excision.

Gastrointestinal Hemorrhage

[Dieulafoy's exulceratio simplex, a life-threatening gastric hemorrhage].

The 'exulceratio simplex Dieulafoy' is an uncommon and probably underdiagnosed cause of upper gastrointestinal haemorrhage. The bleeding is intermittent and even endoscopically often missed. In this article the pathogenesis, diagnostic methods, clinical presentation and therapy are discussed. We present one case treated in our hospital.

Adult

Longitudinal myotomy of ileum for bladder replacement in dogs.

To evaluate the application of longitudinal myotomy of ileum for bladder replacement, pressure/volume characteristics of myotomized ileal segments were studied in dogs after incorporation in the urinary tract. In five dogs a 12 cm. long myotomized ileal segment was incorporated in the left urinary system as a ureteral substitute. These ileal segments did not dilate. In another six animals total cystectomy was carried out and the bladder was replaced by a 12 cm. long myotomized ileal segment. Urodynamic and radiological studies demonstrated early dilatation of these segments, leading to a four-to-five-fold increase in volume after six weeks. During filling the intraluminar pressure remained below 20 cm. H2O up to two-thirds of the maximal volume and gradually rose when filling was continued. High pressure waves were not observed. This study demonstrates that in experimental dogs longitudinal myotomy of a short length of ileum results in a high volume/low pressure urinary reservoir. This technique is easy to perform, requires less bowel compared to current reservoir techniques and leads to satisfactory reservoir function.

Animals

Intraoperative antegrade irrigation in complicated left-sided colonic cancer.

Emergency one-stage surgery for acute, complicated, left-sided colonic cancer can be performed because of intraoperative antegrade irrigation of the large intestine. This procedure was performed in 17 patients: 15 patients with an obstructive, left-sided cancer and two patients with a perforated carcinoma. The age distribution ranged between 57 and 92 years. There were two postoperative septic complications: a small wound abscess and a partial abdominal wall dehiscence. One patient died because of massive upper gastrointestinal bleeding. This method permits the creation of a primary anastomosis in the left colon, obviating the necessity of a coeco- or colostomy, preternatural anus, or an extensive right-sided hemicolectomy. Several surgical interventions are avoided, resulting in a decrease of mortality, morbidity, duration of hospital stay, and costs. Moreover, intraoperative irrigation could be an attractive alternative for the usual preoperative mechanical bowel preparation, which is especially burdensome in elderly patients.

Aged

Soiling: anorectal function and results of treatment.

Forty-five patients with soiling but without faecal incontinence were evaluated by means of anorectal function investigations (anal manometry, rectal capacity and saline infusion test). The causes of soiling and the effect of treatment on both soiling and anorectal function were studied. The results were compared with a control group of 161 patients without soiling or incontinence. The diagnoses were haemorrhoids (10), mucosal prolapse (7), rectal prolapse (6), fistulae (5), proctitis (3), faecal impaction (2), rectocele with intussusception (2), scars after fistulectomy (2) and others (8). Simple inspection and proctoscopy were generally sufficient to establish a diagnosis. For two patients the diagnosis rectocele was made after defaecography. Anorectal test results did not differ between the soiling and control group, did not contribute to establish a diagnosis and did not change after treatment. Only patients with a rectal prolapse had abnormal results in anorectal function tests: a low basal sphincter pressure and a limited continence reserve. Appropriate therapy resulted in complete recovery (44%) or improvement of symptoms (29%).

Anal Canal