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Biomedical subjects

H Edwards

Publications and source records attributed to H Edwards.

At least 73 records · Page 4Linked to original sources

Exercise stress testing and an electromechanical S wave of the electrocardiogram. Does the S-wave voltage change with increasing work rate?

A new view of the electrocardiogram, first proposed by Posel and arising from Craib's travelling dipole concept, predicts an electromechanical relationship between S-wave amplitude changes and cardiac mechanical function changes. In an attempt to determine whether the S-wave voltage changes with increasing work rate, 10 male subjects were tested at rest and at maximum exercise. A statistically significant increase in the S wave occurred with increased mechanical work. The theoretical prediction of an electromechanical S wave is thus validated and a request is extended to other workers to verify or refute its existence.

Electrocardiography↗

Electrocardiographic measurement of cardiac function. Are the amplitude changes of the S wave indicative of changes in the size of the heart?

Preliminary tests to determine whether there is an electromechanical link between the electrocardiogram and cardiac function have been done by means of echocardiography. Three different haemodynamic manipulations which alter cardiac function, viz. nitroglycerin, intravenous digoxin and exercise-induced angina, were used. The changes in the S-wave amplitude, in selected leads, appear to be directionally related to the changes in the left ventricular enddiastolic volume. It is thus suggested that the S-wave changes may be indicative of changes in cardiac function.

Angina Pectoris↗