Theodoric of Cervia, a medieval antiseptic surgeon.
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Biomedical subjects
Publications and source records attributed to H Edwards.
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A new view of the electrocardiogram, first proposed by Posel and arising from Craib's travelling dipole concept, predicts an electromechanical relationship between S-wave amplitude changes and cardiac mechanical function changes. In an attempt to determine whether the S-wave voltage changes with increasing work rate, 10 male subjects were tested at rest and at maximum exercise. A statistically significant increase in the S wave occurred with increased mechanical work. The theoretical prediction of an electromechanical S wave is thus validated and a request is extended to other workers to verify or refute its existence.
Preliminary tests to determine whether there is an electromechanical link between the electrocardiogram and cardiac function have been done by means of echocardiography. Three different haemodynamic manipulations which alter cardiac function, viz. nitroglycerin, intravenous digoxin and exercise-induced angina, were used. The changes in the S-wave amplitude, in selected leads, appear to be directionally related to the changes in the left ventricular enddiastolic volume. It is thus suggested that the S-wave changes may be indicative of changes in cardiac function.
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