Search PubMed⌕ Search

Biomedical subjects

H E Mosso

Publications and source records attributed to H E Mosso.

7 recordsLinked to original sources

[President Agustin P. Justo and the Faculty of Medicine: other times].

In January this year it was the 50 anniversary of Gral. Agustin P. Justo death, who was President of Argentine during the period 1932-1938. His presence was remarkable so because of his good administration as for his helping the cultural, scientific and teachers activities. He was the owner of a valuable library where he had lots of books about American History. During his government the "Junta de Historia y Numismática" became the "Academia Nacional de Historia". He admired Gral. Bartolomé Mitre, and he ordered the publication of his complete work, writing the introduction. He acted in a distinguished time, characterized by a high respect for intellectual and scientific hierarchy, and by the professors of the U.B.A., where he gave prestige to several acts with his presence and honoring the laureates.

Argentina↗

Evaluation of the high density lipoprotein cholesterol protective effect against atherogenesis in rabbits fed cholesterol supplemented diets.

Plasma high density lipoprotein cholesterol (HDL-C) was evaluated in 15 rabbits fed cholesterol supplemented diets to assess its protective effect on the atherogenic process. From a baseline level of 29 +/- 11 mg/dl (mean +/- SD) the maximum attained for HDL-C was twofold in only three rabbits, whereas total cholesterol (TC) increased 20 fold. Plasma TC/HDL-C ratio rose 80 fold from the baseline (2.4 +/- 0.9) and it was the best parameter that correlated with aortic cholesterol accumulation and pathological scores. Aortic TC content increased 10 fold and free cholesterol/cholesterol esters ratio decreased 20 fold. Pathological studies showed that aortic lesion scores rose from 0 to 4. It can be concluded that the high correlations obtained when TC/HDL-C ratio was plotted against both aortic cholesterol deposition and lesion scores, support the theory of the reverse cholesterol transport and the effectiveness of this index to predict the degree of the atherogenic process. On the other hand, the poor response of HDL-C in this model encourages future research using drugs to increase this parameter in order to normalize TC/HDL-C ratio and avoid lesions.

Animals↗