Biomedical subjects
Publications and source records attributed to H E Hildebrandt-Stark.
We present five patients with cystic hygroma: the CT features are presented. It occurs primarily in the region of the neck. Occasional involvement of the axilla, the chest wall and the mediastinum is possible.
We report three patients with neurofibromatosis, lung parenchymal, and pleural changes. Lung fibrosis occurs in 10% of patients with neurofibromatosis. Pleural involvement is less common. We are presenting one such case.
Eight hundred computed tomographic (CT) scans of the chest were reviewed, and 12 cases of episternal ossicles were found. Eight persons had paired ossicles, and four had unilateral ossicles. The overall frequency in the study population was 1.5% (men, 1.4%; women, 1.7%). Episternal ossicles represent a normal variant and should be distinguished from fracture fragments, sequestra, foreign bodies, calcified lymph nodes, or vascular calcifications.
Two pregnant patients presenting with bronchogenic carcinoma are described. A retrospective study of patients with bronchogenic carcinoma as well as a review of the literature attest to the rarity of this combination. If current smoking patterns continue, the association of pregnancy and bronchogenic carcinoma will increase in frequency.
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Adult female guinea pigs were actively immunized with prostaglandin F-2alpha conjugated to bovine serum albumin (BSA). Control animals, immunized against BSA continued to cycle normally, while the animals immunized against prostaglandin F-2alpha stopped cycling after one to three normal cycles. Laparotomy at 30 days after the last estrus revealed no recently formed corpora lutea. During the remaining 70 days of observation the antibody titer increased to 1:700, accompanied by increasing total serum estrogens (136 pg/ml at day 100) and a slow decline in circulating progesterone levels (0.6 ng/ml at day 100). The ovaries at day 100 contained degenerated corpora lutea and luteinized follicles. The suppression of the estrous cycle in the present experiments was interpreted as resulting from prolongation of luteal function as well as from inhibition of ovulation.
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