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Biomedical subjects

H E Fadel

Publications and source records attributed to H E Fadel.

62 records · Page 4Linked to original sources

Realtime sonographic diagnosis of fetal dysplastic kidney.

A case of unilateral renal dysplasia was diagnosed in utero using realtime scanning. The diagnosis was confirmed neonatally and the affected kidney was surgically removed. Pathologic findings were consistent with the features of this malformation. The echographic characteristics of renal dysplasia and the differential diagnosis are described. The potential uses of ultrasonography in the diagnosis and follow-up of pregnancies associated with or at risk of renal malformations are discussed.

Adult↗

Detection of fetal-maternal hemorrhage in a mother with sickle trait and hereditary persistence of fetal hemoglobin.

An Rh-negative term primigravida with sickle trait and hereditary persistence of fetal hemoglobin and an Rh-positive infant were evaluated postpartum for fetal-maternal hemorrhage (FMH) by the acid-elution test for fetal hemoglobin (HbF) cells. Using the acid-elution test, 100 percent of the cells contained HbF. The patient received one vial of Rh immune globulin and was discharged. This report illustrates that lack of specificity is a major problem of the acid-elution test for detection of fetal-maternal hemorrhage, due to its failure to differentiate true fetal Rh-positive cells from maternal Rh-negative HbF cells. Moreover, productivity studies suggest performance of agglutination tests such as the immune rosetting test is more convenient than performance of the acid-elution test to screen for FMH. The recently developed enzyme-linked antiglobulin test, however, may replace both of these procedures for detection of FMH.

Adult↗