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Biomedical subjects

H Dupon

Publications and source records attributed to H Dupon.

At least 37 records · Page 2Linked to original sources

[A new case of epidermolysis bullosa dystrophica in a fifteen years old girl operated upon for pulmonary stenosis with a cardiopulmonary bypass (author's transl)].

The authors encountered technical difficulties for the endotracheal intubation but neither laryngeal damage nor serious oropharyngeal lesions occurred after this intubation. The general evolution was favourable without specific trouble (cutaneous or infectious). The risk of intubation was reexamined from the recent literature. It is generally believed that there is a tendency for the skin to become more resistant to the formation of bullae as the afflicted children grow older. So, when another disease sets vital prognosis in action, major surgical operations can be performed and more especially as the average length of life is now increasing for these patients.

Adolescent↗

[Cardiac surgery under extracorporeal circulation in patients with chronic renal insufficiency. Apropos of 4 cases and review of the literature].

Four cases of cardiac valve replacement in patients with chronic renal failure are reported. The problem of surgery under cardiopulmonary bypass in these patients are discussed with respect to 36 other previously reported cases. Of this lot of 40 cases, 33 (82,5 p.100) underwent valve replacement (21 aortic, 9 mitral, 1 mitral and aortic, and 2 unspecified), 26 (79 p.100) for valvular lesions due to infective endocarditis. Coronary revascularisation was performed in 6 cases (15 p.100) and pericardectomy in 1 case. Operative mortality was within acceptable limits (4 deaths) ; the overall mortality was 10 cases. Valvular lesions due to endocarditis were the main cause of death (9 cases). A session of haemodialysis is performed 12 hours preoperatively. Post-operative care is directed to the control of the fluid balance, the neutralisation of metabolic acidosis with alkaline fluids (sodium lactate) and the correction of hyperkalaemia by kayexalate. In addition, dialysis is required between the 24 th post-operative hour and the 3 rd day. The main indications for cardiac surgery under cardiopulmonary bypass in patients with renal failure are valve replacement for infective endocarditis where the operative decision should be made early on, and aorto-coronary bypass grafting, the selection criteria for which should be very strict.

Adolescent↗

[Intimal coronary fibrous dysplasia and Prinzmetal's angina].

It is currently considered as exceptional for there to be arterial pathology other than atheroma in Prinzmetal angina. The authors have found five cases of coronary fibrous dysplasia in the literature. They add a case, in a woman, of intimal fibrous dysplasia diffusely involving the three main coronary vessels. Coronary arteriography showed that spasm of the right coronary artery was the cause of attacks with the clinical and electrocardiographic features of Prinzmetal angina. The whole coronary tree was otherwise normal angiographically and also macroscopically at autopsy. The dysplasia was only discovered by histological study of serial sections of the three coronary vessels. Histological examination showed no evidence of an atheromatous lesion. The authors place these coronary artery lesions within the general classification of arterial fibrous dysplasias. It remains hypothetical whether there is a relationship between the occurrence of spasm and this very special histological feature of the coronary artery wall.

Angina Pectoris↗

[Vascular complications of exostosis. About an exceptional case of true femoral aneurysm (author's transl)].

An exceptional observation of a true femoral aneurysm complicating an exostosis is related. From a review of 60 cases of the literature, the authors study the different vascular complications induced by osteochondroma. In 3 cases out of 4, the vascular injury consist in a false aneurysm; in 1 case out of 5 vascular compression is the point in question; only 4 cases of true aneurysm have been collected. After study of the different clinical aspects of the disease, the authors emphasize the need of surgical treatment associating removal of exostosis and restoring vascular axis. They suggest preventive removal of exostosis situated on a vascular axis to hinder the onset of such accidents.

Adult↗