Search PubMed⌕ Search

Biomedical subjects

H Davies

Publications and source records attributed to H Davies.

At least 127 records · Page 7Linked to original sources
PubMed1979

Characterization of pig lymphocyte subpopulations by adherence to nylon wool.

The property of adherence to nylon wool was used to separate and characterize pig blood lymphocyte subpopulations. Thymus-dependent null cells proved the least adherent lymphocytes, and B cells, bearing surface Ig or Fc receptor, the most adherent. sIg+ lymphocytes detected by immunofluorescence and by 51Cr release cytotoxicity showed similar frequency and adherence properties. Lymphocytes rosetting with SRBC in PBS or in dextran had similar adherence patterns and showed both non-adherent and adherent components. Lymphocytes bearing major histocompatibility complex (MHC) Ia-like antigens shown by eosin exclusion or 51Cr release cytotoxicity were enriched in the adherent fraction, but also occurred in significant numbers in the non-adherent fraction. Non-adherent Ia+ cells were predominantly sIg- and probably T cells, whereas the adherent Ia+ group included the sIg+ cells and some sIg- cells.

Animals↗
PubMed1979

Observations on voluntary nystagmus.

Unitl recent times, reports concerning voluntary nystagmus have been dismissive, most observers regarding the phenomenon as a form of ocular acrobatics or an amusing party trick. The introduction of sophisticated recording apparatus coupled with renewed interest in ocular kinetics has resulted in a more analytical approach. Clinical and electro-oculographic study of the condition in 5 subjects was undertaken in an attempt to relate voluntary nystagmus to the known mechanisms of oscular movement control. The frequency of the movement varied from 15 to 23Hz and amplitude from 2 to 5 degrees. The wave form was similar to that seen in acquired pendular nystagmus. It was concluded that, depsite differences in frequency, the similarity in form of the movements of voluntary nystagmus and acquired pendular nystagmus suggested a possible identity in the mechanisms of the movements.

Adult↗
PubMed1977

Intrathyroid cystic parathyroid adenoma: a rare case of hyperparathyroidism.

A case is presented of a 52-year-old man with a swelling in the neck and dysphagia resulting from an intrathyroid cystic parathyroid adenoma. Hypercalcaemia and unusually high parathyroid hormone levels were detected preoperatively. The adenoma was removed by partial hemithyroidectomy. The literature is reviewed.

Adenoma↗
PubMed1976

Homograft and prosthetic aortic valve replacement: a comparative study.

Homograft aortic valve replacement was done in 103 patients and prosthetic aortic valve replacement in 106 between January 1962 and December 1973. Patients who received homograft and prosthetic valves were compared with respect to age, sex, preoperative functional impairment, infection, dyspnea, angina, hemodynamics, chest X-ray, electrocardiogram, associated operations, early and late mortality, and valve failure. Combined total mortality was 28% (12% operative, 8% first postoperative year, 8% late). Ten percent of valve required replacement. One year after operation, 70% of survivors were asymptomatic, 27% were improved, and 3% were unchanged or between homograft and prosthetic valve replacement. Valve-related failure and infections were more common after homograft aortic valve replacement. Emboli, hemorrhage, and hemolysis were commoner after prosthetic valve replacement. Fungal infections occurred in five homograft patients but in no patient with a prosthetic aortic valve. Severe properative symptoms or recent endocarditis was associated with greater mortality and valve failure in both the homograft and the prosthetic series. Increased mortality and failure was also seen in patients with either preoperative aortic regurgitation with high left ventricular end-diastolic pressure and low cardiac index, or aortic stenosis with cardiomegaly or roentgenographic evidence of congestive heart failure. Therefore, in two series of patients at equal risk, mortality and valve failure were similar for homograft and prosthetic aortic valve replacement.

Adolescent↗
PubMed1975

Epidemic viral enteritis in a long-stay children's ward.

Two outbreaks of acute gastroenteritis occurred in 1974 in a long-stay children's ward. Electron microscopy demonstrated rotaviruses in faeces from the affected children in the first outbreak, and adenoviruses in faeces from affected children and a nurse in the second outbreak. The illness in both outbreaks was very mild; but the diarrhoea associated with rotavirus infection usually lasted 5-8 days (in one patient it lasted for 28 days) and sometimes started with vomiting; whereas the adenovirus-associated diarrhoea lasted only 2-4 days and was not associated with vomiting. Neither the rotaviruses nor the adenoviruses could be established in tissue-culture.

Acute Disease↗
PubMed1975

Left ventricular ejection fraction in severe chronic obstructive airways disease.

The subject of left ventricular involvement in chronic obstructive airways disease is controversial. We measured left ventricular ejection fraction (LVEF) in 120 patients with severe chronic obstructive airways disease, 92 of them acutely decompensated and 28 stable. A bedside radionuclide technic using a scintillation probe was used to measure LVEF. Of the 28 patients with acute respiratory failure, LVEF was normal (larger than or equal to 55 per cent) in 60 and subnormal in 32. Of the 28 patients with stable chronic obstructive airways disease, LVEF was normal in 12 and low in 16. Coronary artery disease could be demonstrated clinically or at autopsy in 13 of the patients with acute and in 7 of the patients with stable chronic obstructive airways disease. LVEF was 28 plus or minus 10.4 per cent (average plus or minus SEM) in the patients with acute chronic obstructive airways disease and coronary artery disease which was significantly different (P smaller than 0.001) from LVEF in patients without coronary artery disease (61 plus or minus 1.9 per cent). In the patients stable with chronic obstructive airways disease and coronary artery disease, LVEF was (42 plus or minus 3.5 per cent), significantly different (P smaller than 0.001) from LVEF in those without coronary artery disease (55 plus or minus 2.1 per cent). There was no relationship between LVEF and arterial oxygen, or carbon dioxide tension, or pH. Results suggest that LVEF is normal in patients with severe lung disease alone and that reduced LVEF in patients with chronic obstructive airways disease can reasonably be ascribed to coronary artery disease.

Acute Disease↗
PubMed1975

Transmission of human rotaviruses to gnotobiotic piglets.

Faecal filtrates containing rotavirus particles, from children with acute infectious diarrhoea, were inoculated intranasally into gnotobiotic piglets. The piglets developed no symptoms, but birus was readily found by electron microscopy in their faeces during three serial passages. Among 11 piglets tested 3 weeks after inoculation of virus, all had developed fluorescent antibodies against tissue-culture-adapted calf rotavirus but only two had neutralising antibody. Growth of human rotavirus did not occur in either normal or "nude", thymus-deficient suckling mice.

Agglutination↗
PubMed1975

The square left ventricle: an angiographic and radionuclide sign of left ventricular thrombus.

The association of mural thrombus with left ventricular aneurysm is well documented, though angiographic documentation of left ventricular thrombus can be difficult. The authors describe the unique appearance of the left ventricular cavity in 5 patients. In all cases, ventriculograms obtained in the right anterior oblique position showed a squared apex. In 2 patients this phenomenon was also demonstrated by radionuclide angiocardiography. All 5 patients were found to have left ventricular thrombus at operation or autopsy.

Angiocardiography↗