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Biomedical subjects

H D Hall

Publications and source records attributed to H D Hall.

At least 73 records · Page 4Linked to original sources

Neurally mediated increase in mitosis and DNA of rat parotid with increase in bulk of diet.

A transient burst of mitosis was induced in rat parotid gland 2 days after change from a diet of solid chow only to one consisting of 50% inert cellulose and 50% solid chow (bulk diet). Mitosis was thus induced when glandular activity was changed from normal levels (solid chow) to levels greater than normal (bulk diet). Elimination of either autonomic pathway inhibited the mitotic response, but elimination of the parasympathetic had the greater inhibitory influence. The burst of mitosis induced by bulk diet was followed by increases in total DNA (16%), RNA (24%) and weight (27%) of the gland 2 wk after the dietary change. These changes did not occur when both autonomic pathways were, or only the parasympathetic was, removed immediately prior to the dietary change. Effects of sympathectomy were less pronounced. The parasympathetic innervation has the principal role in regulation of mitosis, cell number and size, and nucleic acid content when glandular activity is increased above normal by physiological means.

Animals↗

Combined anterior and posterior maxillary osteotomy.

The combined anterior and posterior maxillary osteotomy is primarily indicated for maxillary alveolar hyperplasia. Treatment planning is somewhat more complex than usual for the combined procedure. A method for developing a treatment plan is presented. In contrast to the anterior maxillary osteotomy, the technique for posterior osteotomy is relatively new and has had several recent modifications. Guidelines are presented for rational selection of a specific combined technique. The results obtained with the combined technique have not been well documented. Nonetheless, results appear to be stable and complications are infrequent.

Adolescent↗

Parasympathetic regulation of mitosis induced in rat parotid by dietary change.

Mitotic activity of rat parotid was increased from levels near zero to 10-40 mitotic figures per 1,000 acinar cells (mean, 15/1,000) 2 days after glandular activity was increased from less than normal to normal by replacing liquid diet with a diet of solid chow. This frequency greatly exceeded the maximum (1-3/1,000 acinar cells) observed at any time during the diurnal mitotic fluctuations. This mitotic burst was virtually prevented if the auriculotemporal nerve was removed 2 days prior to introduction of solid chow, but was only somewhat reduced when the superior cervical ganglion was removed prior to the dietary substitution. The parasympathetic innervation also was chiefly responsible for the increased cell size that followed reintroduction of solid food.

Animals↗

Evaluation and refinement of the intraoral vertical subcondylar osteotomy.

Data were collected from the use of intraoral vertical subcondylar osteotomy in 42 patients. The results of treatment compare favorably with those attained with sagittal split osteotomy and extraoral vertical subcondylar osteotomy. Modification in instrumentation and techniques has further improved the intraoral vertical subcondylar osteotomy. The primary advantage of this technique compared to the sagittal split osteotomy is the much less frequent and less severe damage to the mandicular nerve. This intraoral technique deserves serious consideration as the method for reduction of the prognathic mandible.

Humans↗