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Biomedical subjects

H D Attwood

Publications and source records attributed to H D Attwood.

At least 19 recordsLinked to original sources
PubMed1988

Some specimens from William Clift's copy of Matthew Baillie's The Morbid Anatomy of the Human Body (1799-1802).

Recently in reproducing Matthew Baillie's classic atlas of morbid anatomy using an almost complete set of the original drawings of William Clift an attempt was made to give a modern diagnosis of all the conditions illustrated. Some of the many memorable specimens are here described and illustrated. The Morbid Anatomy of the Human body is published by Melbourne University Press.

Anatomy, Artistic↗
PubMed1988

Lymphohistiocytoid mesothelioma: a rare lymphomatoid variant of predominantly sarcomatoid mesothelioma.

Of 394 "definite" mesotheliomas entered in the Australian Mesothelioma Surveillance Program, three bore a striking resemblance to malignant lymphoma by conventional light microscopy, and each was misinterpreted at some stage as lymphoma. The lymphoma-like morphology was a combined result of intense lymphoplasmacytic infiltration and the histiocytoid appearances of the underlying neoplastic cell population. Immunocytochemical analysis demonstrated cytokeratins coexpressed with vimentin within the tumor cells, whereas immunoreactivity for leukocyte common antigen was confined to the smaller lymphoid cells. Electron microscopy of two cases revealed a polymorphous population of fibrohistiocytic cells resembling those typical of malignant fibrous histiocytoma, admixed with lymphocytes and plasma cells, but sporadic cells expressed mesothelial properties in the form of sinuous villiform processes, intracytoplasmic neolumina lined by microvilli, and intermediate filaments that were aggregated into tonofilament bundles in some cells. The ultrastructural appearances, the localization of the tumors to the pleura, with effusion, and absence of anterior mediastinal mass lesions facilitated exclusion of lymphocyte-rich thymoma. In addition, a history of prior occupational exposure to asbestos was elicited in each instance. There was no apparent response to radiotherapy or chemotherapy, and the patients died at 4, 5, and 8 months after presentation. Our observations suggest that immunocytochemical or ultrastructural evaluation is mandatory for accurate diagnosis of all pleura-based lymphomatoid lesions with a mixed large and small cell pattern.

Aged↗
PubMed1980

Pancreatic pathology in dasyurid marsupials.

The pancreas of 231 dasyurid marsupials was examined. Focal intestinal pancreatitis was found in 22 animals, an exocrine adenoma in an Antechinus macdonnellensis and in islet cell adenoma in an Antechinus apicalis. Glycogenic vacuolation of islet cells found in one Antechinus sp. nov. and one Antechinus rosamondae is taken as evidence for spontaneous diabetes mellitus.

Adenoma↗
PubMed1980

Rupert Willis.

Explore the source record for details and available documents.

Australia↗
PubMed1979

An investigation of the route and progression of Encephalitozoon cuniculi infection in adult rabbits.

Rabbits infected either orally or intratracheally with cell culture-grown Encephalitozoon cuniculi were monitored regularly for serum antibody levels and E. cuniculi in the urine. Their responses were compared with intravenously inoculated and uninoculated control rabbits. All rabbits receiving E. cuniculi developed serum antibodies, generally within 3 weeks, and excreted E. cuniculi by 6 weeks. In the acute stage of infection, the organs most affected were lung, kidney and liver; the brain and gut were unaffected. However, during chronic infection, the brain, kidney, and heart were the only organs found to be involved. Antibody levels were very high at this stage. Thus both the oral and tracheal routes may be normal routes of infection with E. cuniculi in adult rabbits.

Animals↗
PubMed1978

The longevity of Clonorchis sinensis.

The persistence of Clonorchis sinensis infestation of the bile duct for a period of at least 26 years without neoplasia supervening is reported in a Chinese immigrant to Australia.

Aged↗
PubMed1975

Toxoplasmosis in dasyurid marsupials.

During a histopathologic survey of 240 dasyurid marsupials a high prevalence of infection of Toxoplasma gondii was found in eight of thenine species examined. Amongst the infected species, endemic infection in field animals was proved in Dasyuroides byrnei, but there was also good evidence of laboratory infection probably derived from raw sheep tissues in their diet. Infection was never demonstrated in animals less than six months of age. The 21 Antechinus stuartii examined remained free from infection despited a lengthy stay in the laboratory and a similar diet. This freedom from infection may indicate a particular resistance to Toxoplasma infection by this species.

Animals↗