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Biomedical subjects

H Carrasco

Publications and source records attributed to H Carrasco.

42 records · Page 3Linked to original sources
PubMedDate not supplied

[Electrocardiographic evaluation of the cardiotoxicity of N-methylglucamine antimonate (R glucantime)].

The heart toxicity of N-Methyl-glucamine antimoniate (R glucantime) was studied by electrocardiographic readings in 16 patients with acute cutaneous Leishmaniasis. All patients studied came from the town of Tovar and it's surrounding areas, in the district of Tovar, Merida State, Venezuela. A dosage of 25 to 50 mg/kg/day of N-Methyl-glucamine in two or three treatment series, produced the healing of the cutaneous sore, without electrocardiographic alterations which could be interpreted as signs of myocardial toxicity.

Adolescent↗
PubMedDate not supplied

[Mitral valve and left ventricular function in ostium secundum type interatrial communication, studied by left ventriculography].

Clinical, hemodynamic and cineangiographic studies were performed in 11 patients with atrial septal defect (ASD) of ostium secundum type. Mitral valve prolapse was found cineangiographically in 9 cases. Systolic and diastolic left ventricular volumes were significantly increased, while left ventricular function and compliance were normal. A careful systematic exploration of mitral valve in patients with ASD ostium secundum seems to be advisable.

Adolescent↗
PubMedDate not supplied

[Diagnosis by non-invasive methods of incipient left ventricular lesions in patients with Chagas' disease. Use of echocardiography and mechanocardiography].

In this study, ninety-seven patients with positive complement-fixation reaction for Chagas' disease were submitted to M-mode echocardiograms, fonomechanocardiograms, right and left heart catheterization and left cine-ventriculogram, in an attempt to establish the usefulness of these non-invasive methods for the diagnosis of myocardial damage in Chagasic patients. Only the left ventricular end-diastolic volume determination showed a significant echo-angiographic correlation, as well as a satisfactory sensitivity and specificity to detect early myocardial damage. Therefore, with this parameter it was possible to diagnose 33% of patients which had left ventricular cine-angiographic damage, without clinical, electrocardioangiographic or radiological abnormalities. All other non-invasive parameters measured in this study were useful only in patients with advanced myocardial damage, recognizable by abnormal ECG or clinical signs of congestive heart failure. We recommend to obtain good quality left ventricular ecocardiograms in every chagasic patient, particularly those with normal ECG. This will allow the diagnosis of incipient cardiomyopathy in almost one third of all chagasic patients with early left ventricular abnormalities, recognizable by cine-ventriculograms.

Chagas Cardiomyopathy↗