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Biomedical subjects

H Cammann

Publications and source records attributed to H Cammann.

6 recordsLinked to original sources
PubMed2003

[An artificial neural network as a tool in risk evaluation of prostate cancer. Indication for biopsy with the PSA range of 2-20 microg/l].

In this prospective study covering 5.5 years we evaluated the diagnostic power of an artificial neural network (ANN) based on PSA, %fPSA, and clinical data in the PSA range 2-20 microg/l as prostate biopsy indicator. A total of 944 patients with prostate cancer or benign hyperplasia (BPH) were analyzed. The calculation of the individual patient's risk before prostate biopsy was performed at the 90% and 95% specificity and sensitivity levels within the PSA ranges 2-4, 4.1-10, and 10.1-20 microg/l. For the low PSA range 2-4 microg/l, we recommend a first time biopsy at an ANN specificity level of 95%. For PSA range 4.1-10 microg/l, we recommend a first time biopsy at an ANN sensitivity level of 95%. A rebiopsy at the PSA range 10.1-20 micro g/l should be performed based on a 95% sensitivity level. The use of an ANN at PSA 2-20 microg/l enhances the specificity and sensitivity of %fPSA by 9-39%. The application of an ANN based on %fPSA and clinical data improves the diagnostic performance compared to %fPSA only.

Adult↗
PubMed1995

Computerized dynamic electrocardio-respirography with psychic load: new possibilities for preventive health care.

Proceeding from the role played by psychic load as a pathogenetic factor, its mechanism of action and its predominant importance in every-day life, a computerized system-analytical method was developed by which regulatory disorders may be realized under close-to-reality psychic load as possible risk factors or precursors of organically manifest illness. The method has already been introduced for routine preventive diagnostics under the heading of dynamic electrocardiography with standardized psychic load since cardiac arrhythmia, due to psychic load, has proved to be of particular relevance to preventive health care. The conditions for preventive health care and for further elucidation of psychophysiological regulation behavior have been substantially improved by its recent expansion to the level of dynamic electrocardio-respirography which additionally enables differentiated regulation-diagnostic evaluation of the respiratory system and its close interrelations with the cardiovascular system.

Adult↗
PubMed1982

Measurement of psychophysiological and personality factors in men with ischaemic heart disease.

Essential features of the methods and results of an automated system-analytic investigation procedure with well-defined psychic load are described. This was developed with the aim of recognizing disturbances in the psychophysiological system behaviour as premorbid stages of the most important cardiovascular diseases. Results thus obtained show a.o. that healthy subjects and patients suffering from ischemic heart disease can be classified with high reliability according to their psychophysiological system behaviour. A differentiation could be obtained as well on the basis of personality characteristics. The results support the hypothesis underlying the development of this procedure.

Adult↗