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Biomedical subjects

H C Engell

Publications and source records attributed to H C Engell.

At least 55 records · Page 3Linked to original sources
PubMed1978

Central haemodynamics during induction of neurolept anaesthesia in patients with arteriosclerotic heart disease.

The haemodynamic changes occurring during induction of neurolept anaesthesia and intubation in patients with reduced cardiac reserve were compared with the haemodynamic changes observed prior to operation during the stress of moderate physical exercise in the same patients. Anaesthesia consisted of droperidolum NFN (Dehydrobenzperidol), fentanyli citras NFN (Haldid) and nitrous oxide-oxygen with suxamethonium for intubation. The haemodynamic parameters measured were mean arterial blood pressure, central venous pressure, pulmonary artery mean pressure, pulmonary capillary wedge pressure and cardiac output. Blood volume was also measured, as were arterial blood-gas tensions and pH. The haemodynamic changes observed during induction with intubation were significantly smaller than those observed preoperatively during exercise.

Aged↗
PubMed1978

Blood volume and hemodynamic changes in relation to extensive vascular operations.

In 37 patients without cardiopulmonary insufficiency, postoperative changes in blood volume have been correlated to changes in the systemic and the central circulation. Postoperatively, the blood volume had decreased an average of 8 per cent, and diastolic blood pressure, 7 per cent, while cardiac index had increased 14 per cent and heart rate, 16 per cent. No significant changes could be demonstrated in pulmonary artery pressures, central venous pressure or invascular resistance. A highly significant correlation between the blood volume and pulmonary artery pressures and a significant correlation between the blood volume and central venous pressure were noted. Hematocrit was negatively correlated to vascular resistance. It is concluded that an unchanged blood volume during the first postoperative hours results in increased pulmonary artery pressures and central venous pressure. Therefore, in patients suspected of having increased pulmonary artery pressures, complete restoration of blood volume should take place over some hours postoperatively. An increase in hematocrit over normal values should be avoided.

Blood Pressure↗
PubMed1977

Splanchnic blood flow in patients with abdominal angina before and after arterial reconstruction. A proposal for a diagnostic test.

The diagnostic value of determining the splanchnic blood flow (SBF) and oxygen uptake before and after a test meal in patients suspected of abdominal angina was investigated in 15 patients with unexplained abdominal pain. Six patients with typical abdominal angina and occlusive lesions of two or three splanchnic arteries were investigated before and after successful arterial reconstruction. Five patients with less severe arterial lesions were classified as suspected of abdominal angina and four patients with eventual normal arteriography served as controls. No significant difference was found in fasting SBF between the three groups. Postprandial SBF rose in the controls and in the abdominal angina suspected group, but not in the patients with abdominal angina. After arterial reconstruction fasting SBF was higher than before and postprandial SBF rose to the level of the controls. No difference in oxygen uptake before or after test meal was seen in any of the groups or after arterial reconstruction.

Abdomen↗
PubMed1976

Cardiac output measurement by thermal dilution: reproducibility and comparison with the dye-dilution technique.

Cardiac output estimates by the principle of thermodilution (COth) was compared with dye-dilution estimates (COdye) in pigs. For COth estimates a Swan-Ganz 7 F floating thermodilution catheter and a 9500 Edwards Computer, were used. The COdye estimates were obtained by the apparatus constructed by Zijlstra and Mook. The effect of the thermistor position in the pulmonary artery on the COth estimates was also investigated. The reproducibility of COth was examined by duplicate determinations. Based on 101 simultaneous estimates of COth and COdye the correlation was found COth = 1.020 COdye + 0.2378, r = 0.971 for cardiac outputs between 0.65 l/min and 11 l/min. For 111 duplicate determinations of COth between 2 and 9 l/min the coefficient of variation was 4.74%. The thermistor position in the pulmonary artery had no influence on the COth estimates provided an undamped pressure curve could be monitored from the tip of the catheter. Cardiac output can thus be measured rapidly with good accuracy also for low values by means of a blindly inserted thermistor catheter positioned without x-ray control and a computer with digital display.

Animals↗
PubMed1976

Acute mesenteric infarction caused by small vessel disease.

A case of acute mesenteric infarction caused by small vessel disease is reported. The patient recovered after 2 operations by which extensive bowel-resections were performed. The resected bowel showed intimal hyperplasia and atherosclerosis of the small mesenteric arteries. Since also thrombocytosis and increased platelet aggregation was demonstrated the main cause of thrombosis however is supposed to be hypercoagulability.

Acute Disease↗
PubMed1976

High occlusion of the abdominal aorta.

In the period 1969-1976 27 patients have been operated for high occlusion of the abdominal aorta. The patients had a high frequency of concomitant arteriosclerotic involvement of other parts of the cardiovascular system. The over all mortality was 11 per cent, the 3 deaths were all related to simultaneous operation on the renal arteries. The renal arteries were not operated upon in the other 24 cases. The operative morbidity was low and the prognosis is good as there have been no late death, and 83 per cent of the patients are free of recurrence throughout the follow-up period (mean 2.1 years, range 3 months-7 years).

Adult↗
PubMed1975

A comparison between the changes in the distribution volumes of inulin and [51Cr]EDTA after major surgery.

In 12 patients undergoing major surgery the distribution volumes of inulin (V1) and [51Cr]EDTA (V-E) were measured simultaneously by a single injection technique the day before and the day after the operation. Preoperatively V-I was correlated to V-E, and both these volumes were correlated to the plasma volume (PV). Postoperatively only the correlation between V-I and PV was found. The changes in V-I and PV were significantly correlated, but there was no correlations between the changes in V-I and V-E or between the changes in these volumes and in the body weight. Inulin seems to be a better tracer than [51Cr]EDTA, but the lack of correlation between the changes in V-I and V-E and the changes in body weight raises some doubts as to the physiological significance of the measured changes.

Blood Volume↗