Search PubMed⌕ Search

Biomedical subjects

H C Dominick

Publications and source records attributed to H C Dominick.

At least 37 records · Page 2Linked to original sources
PubMed1983

[Fever in children].

Explore the source record for details and available documents.

Anti-Inflammatory Agents, Non-Steroidal↗
PubMed1979

[Rotavirus infections in children (author's transl)].

In 43 out of 90 children suffering from acute gastroenteritis Rotaviruses could be identified in stool-specimens by electronmicroscopy. Symptoms were watery diarrhoea (100%), vomiting (88%), fever (77%), dehydration (47%) and upper respiratory tract infection (21%). In 3 out of 9 patients liver involvement could be documented. In 29 children i.v.-fluid therapy for 1-2 days was necessary. Only in 1 patient severe diarrhoea persisted for 11 days.

Acute Disease↗
PubMed1979

[Suppurative parotitis in newborns (author's transl)].

Neonatal suppurative parotitis is described in 6 patients followed by a review of the literature. About 30-40% of the patients were premature, dehydration constitutes a predisposing factor. Infection occurs usually by bacteria ascending the duct. In 5 of our 6 patients infection had been caused by staphylococci; E. coli was found in 2 patients and pseudomonas in 1 patient. The parenteral therapy with antibiotics is usually sufficient.

Dehydration↗
PubMed1979

[Neonatal hypoglycemia (author's transl)].

The paper describes the symptomatology, pathophysiology, diagnostics and therapy of neonatal hypoglycemia. Early diagnosis is required to prevent brain damage due to hypoglycemia. In addition to conventional enzymatic blood glucose determination a new test strip sensitive for lower concentrations enables the diagnosis exactly.

Birth Weight↗
PubMed1979

[Determination of low blood glucose levels in newborns with the reflectance photometer (author's transl)].

The paper reports the examination of a new test strip Reflotest-Hypoglycemie, which was developed specifically for the hypoglycemic range. In 2 series of 110 respectively 120 samples of capillary blood taken from premature and full term infants the blood glucose concentrations were determined using Reflotest-Hypoglycemie and the hexokineasured with the test strip agree well with the results of hexokinase method in a range less than 50 mg/dl. Bilirubin and hematocrit values do not affect the glucose test. Glutathion and ascorbic acid interfere with the test strip method but this error is neglectable because of physiological low concentrations of these substances.

Blood Glucose↗
PubMed1977

[Magnesium concentration in erythrocytes and plasma in childhood (author's transl)].

In 243 children of various ages the magnesium concentration was determined simultaneously in erythrocytes and plasma. The analysis began in the mother immediately after delivery, in the umbilical vein and in the newborn infant, and ended at school age (6-14 years). The magnesium concentration in plasma as well as in the erythrocytes showed a constant tendency to increase. Statistically significant differences occurred between the age group 1-7 days on the one hand and 2-6 weeks on the other, and also between school children and adult controls (n=20). The adult controls also differed statistically from mothers following delivery.

Adolescent↗
PubMed1976

[The clinical importance of magnesium during neonatal life (author's transl)].

By atomic absorption spectrophotometry (ASS) the magnesium levels in the serum of 50 mothers, their mature healthy infants and the umbilical vein and the umbilical artery were determined. The differences between maternal and neonatal levels and between umbilical vein and umbilical arteries are statistically significant. The results were as follows: Antecubital venous blood of the mother 1.41 +/- 0.38 mval/1, umbilical vein serum 1.59 +/- 0.35 mval/1, umbilical artery 1.65 +/- 0.36 mval/1, neonate 1.68 +/- 0.45 mva1/1. The magnesium concentration in the erythrocytes of neonates was determined for the first time by AAS analysis. A marked variation of the normal was found. It is possible that the determined low magnesium concentrations in the erythrocytes of neonates were due to latent magnesium deprivation in these infants. The mean values for the erythrocytes of the mother (4.38 +/- 1.16 mva1/1) and the erythrocytes from the umbilical vein (3.99 +/- 1.50 mva1/1) differed significantly, whereas the erythrocytes from the umbilical vein and from the peripheral venous blood of the neonate showed no statistically significant difference. Hypomagnesiumia and hypermagnesiumia are described in brief.

Erythrocytes↗
PubMed1975

Isoenzymes of alkaline phosphatase in the serum of patients with cystic fibrosis.

In 36 children with cystic fibrosis (CF) the isoenzymes of alkaline phosphatase (AP) were determined microelectrophoretically in polyacrylamide- and starch-gel. The study was done to evaluate the clinical significance of these additional data for the diagnosis of liver involvement in DF. The results led to the following conclusions: 1. Serum activity of total AP is comparatively unsensitive "masking" alterations in the isoenzyme pattern contributing to the AP serum activity. 2. In 17 children resp. 47% bile-duct phosphatase was increased indicating a secretostasis while other marker enzymes of cholestasis were normal in part. 3. The activity of bone phosphatase in the serum showed a significant correlation to the degree of growth retardation in these patients. 4. Intestinal phosphatase was present in the serum of only one child with cirrhosis of the liver being an indicator for liver insufficiency. 5. Determination of AP isoenzymes in the serum may provide additional information about the organs involved for the physician in handling CF patients.

Adolescent↗
PubMed1975

Subacute necrotizing encephalomyelopathy. Clinical, ultrastructural, biochemical and therapeutic studies in an infant.

Subacute necrotizing encephalomyelopathy (SNE) has been observed in an infant with regressing psychomotor development. The concentrations of alanine, pyruvate and lactate were increased in the serum and blood as well as in the cerebrospinal fluid. Pyruvate carboxylase activity was reduced in the liver tissue. An inhibitor of thiamine-pyrophosphate-ATP-phosphotransferase was present in the urine. Thiamine treatment was followed by a decrease of serum alanine and blood pyruvate and lactate, but there was no clinical improvement during a period of 17 months. Ultrastructural investigations revealed high glycogen levels in liver tissue and skeletal muscle. These findings contrast with decreased gluconeogenesis, which is suggested by the diminished pyruvate carboxylase activity. Therefore it is concluded that reduced hepatic pyruvate carboxylase activity is not the primary cause of SNE.

Alanine↗