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Biomedical subjects

H C Cecil

Publications and source records attributed to H C Cecil.

At least 55 records · Page 3Linked to original sources
PubMed1971

Nonconversion of o,p'-DDT to p,p'-DDT in rats, sheep, chickens, and quail.

The finding of appreciable quantities of p,p'-DDT after feeding o,p'-DDT to rats led to the proposal of a theory, that an isomeric metabolic conversion occurs. The presence of p,p'-DDT as an impurity in supposedly pure samples of o,p'-DDT is the correct explanation for the appearance of p,p'-DDT. Purified o,p'-DDT and (14)C-labeled o,p'-DDT yielded no data to support the idea that o,p'-DDT is converted to the p,p'-DDT isomer.

Adipose Tissue↗
PubMed1968

Estrogenic activity of o,p'-DDT in the mammalian uterus and avian oviduct.

When rats and birds were treated with o, p-DDT, their reproductive tissues exhibited the same response as when they were treated with estrogen. Weight, water content, glycogen, and RNA increased in uteri and oviducts of rats, chickens, and quail receiving o, p-DDT; p, p-DDT produced little if any response. The o, p-DDT did not accumulate in the reproductive or adipose tissues to a greater extent than p, p-DDT.

Animals↗