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Biomedical subjects

H C Anton

Publications and source records attributed to H C Anton.

15 recordsLinked to original sources

Thinning of the clavicular cortex in adults under the age of 45 in osteomalacia and hyperparathyroidism.

A study involving 18 patients shows that thinning of the upper cortex of the clavicle in adults under the age of 45 is most commonly due to renal osteodystrophy or coeliac disease. Cortical thinning should not therefore be regarded as synonymous with osteoporosis. Cortical thinning is usually associated with clavicular erosion in renal osteodystrophy but not in osteoporosis or osteomalacia. The radiological diagnosis of coeliac disease is suggested when thinning of the clavicular cortex is combined with air--fluid levels on abdominal radiography in a patient under the age of 45 years.

Adolescent

The diagnosis and assessment of abdominal aortic aneurysms by ultrasonography.

A study of 150 patients examined by ultrasonography is described. It was designed specifically to diagnose and investigate abdominal aortic aneurysms. Sixty-four aneurysms were found. Ultrasonography was useful in distinguishing aneurysms from other conditions and there was a high degree of correlation between size measured by scanning and operative size. In addition to the demonstration of rupture it was possible to perform serial measurements. The technique is simple and quick and causes minimal disturbance to the patient.

Aorta, Abdominal

The value of ultrasonography in the diagnosis of abdominal aortic aneurysm.

An evaluation of ultrasonography in early dilatation and aneurysm is presented. Fifty-nine patients with prominent abdominal pulsation were examined and aneurysm was demonstrated in 22. There was a high degree of correlation between the size of the aneurysm demonstrated by ultrasound and the size displayed at operation. It was also possible to demonstrate increasing dilatation by measurement on subsequent occasions.

Adult

Generalised and localised bone loss in patients with rheumatoid arthritis.

Osteoporosis was studied in 307 patients with "definite" or "classical" rheumatoid arthritis by measurement of the clavicular cortical thickness (C.C.T.). Bone loss, as measured by this index, fell with advancing age, and was significantly greater than in non-rheumatoid control subjects matched for age and sex. Bone loss from the clavicles was not greater in patients treated with corticosteroid drugs. Loss of bone from the clavicle correlated with osteoporosis in other parts of the skeleton, as determined by the femoral and metacarpal indices. This suggests that osteoporosis in rheumatoid arthritis is a generalised phenomenon rather than a localised process secondary to adjacent joint inflammation.

Adrenal Cortex Hormones

Width of clavicular cortex in osteoporosis.

Thinning of the upper cortex of the clavicle, measured on a standard chest radiograph, may help in the diagnosis of osteoporosis. No precise level at which osteoporosis occurs can be given, but a reading of 1.5 mm. or under is indicative of osteoporosis, while a smaller incidence is associated with readings of 2 mm. and above. There is significant correlation between thinning of the clavicular cortex and other radiological indications of osteoporosis. Thinning may occasionally point to unsuspected bone disease, in osteomalacia as well as in osteoporosis. As chest radiographs are taken in a high proportion of both outpatients and inpatients, the method has a wide applicability.

Adult