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Biomedical subjects

H Bujar

Publications and source records attributed to H Bujar.

41 records · Page 3Linked to original sources
PubMedDate not supplied

Study of mediastinal and lung involvements in Hodgkin's disease.

Clinical, biological, radiological and radioisotope investigations in 224 patients with Hodgkin's disease revealed a great frequency (100 cases, i.e. 44%) of mediastinal and pleuro-pulmonary involvements, most of them in advanced stages of the disease. The predominant histologic types in these cases were mixed cellularity or nodular sclerosis. Evolution and prognosis were improved by combination chemotherapy in COOP courses; X-ray therapy was associated after drug therapy only if absolutely necessary, on limited areas.

Hodgkin Disease↗
PubMedDate not supplied

[Lower limb lymphography in moderate lymphodynamic disturbances (author's transl)].

Based on the analysis of 87 pathologic complementary lymphangiographies of the lower limbs performed concomitantly with a lymphographic check-up of the pelvi-abdominal lymph nodes in various diseases, the authors have tried to establish the relationships of the moderate secondary disturbances of the lymph flow with the different pathologic antecedents affecting the lower extremities and their clinical symptoms. Emphasis is layed on the non-specificity of the early and delayed lymphangiographic aspects. The widest semeiology was recorded in phlebites and the less marked in arthroses. The more numerous and severe the antecedents, the more evident were the clinical and lymphographic signs. Penetrating wounds have a long lasting effect on the lymphatic walls. Lymphodynamic disturbances may occur in many pathologic states, phlebites, certain skin diseases, traumas. The therapeutic implications of these observations are discussed.

Female↗
PubMedDate not supplied

Relationships between lymphography and the histologic nodal and splenic types in Hodgkin's disease. Considerations on clinical evolution.

Trying to establish the eventual interrelations of the initial histologic nodal type and the splenic one, the general lymphographic picture, the histologic nodal type and spleen involvement, lymphographic and histologic examinations were carried out in 151 patients with Hodgkin's disease. Lympographies were performed in 139 cases, and splenectomy (followed by splenic, hepatic and abdominal lymph node biopsies) in 32. Lymphocyte depletion was found in 72.7% of the patients with lymph node obstruction diagnosed lymphographically. Splenic involvement was more frequent in cases with pathologic lymphographic picture and histologic aspects of lymphocyte predominance or nodular sclerosis. In patients with initial nodal histologic types of nodular sclerosis or lymphocyte depletion, the splenic histopathologic types were the same, but they got more severe in cases with lymphocyte predominance or mixed cellularity. Splenic biopsy might be unconclusive after protracted cytostatic treatment or splenic X-ray therapy. In the authors' opinion, early routine splenectomy is rather more advisable than differentiated splenectomy.

Hodgkin Disease↗