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Biomedical subjects

H Bucht

Publications and source records attributed to H Bucht.

At least 37 records · Page 2Linked to original sources
PubMed1981

Mesangial IgA glomerulonephritis in adults. Clinical and histopathological observations.

This report evaluates 29 patients with IgA glomerulonephritis. Patients with the least intensity of immunofluorescent staining for IgA had the highest glomerular filtration rate. The pattern or intensity of the staining gave little or no indication of the severity of the morphological changes or of the short-term prognosis. Histological changes with increased amounts of adherences were found in a significantly higher proportion of kidneys with decreased function. Older patients had a longer history and a higher incidence of low renal function, and they showed more glomerular adherences and global fibrosis than younger patients.

Adolescent↗
PubMed1980

Active treatment of uremia in the city of Göteborg 1966-1977.

137 patients were actively treated because of chronic uremia, during 1966 to 1977 in the city of Göteborg. One year patient survival increased from 51% (1966 to 1968) to 81% (1975 to 1977). Peritoneal dialysis decreased as the initial mode of treatment, and only 3% of the patients started dialysis treatment with this mode of therapy in the last 3-year period. Mean age of the actively treated patients was 44 years. A decreasing mean age of the actively treated patients was found towards the end of the period, reflecting more liberal criteria for accepting young patients with different systemic diseases. If the initial mode of treatment was dialysis, 1-year patient survival in the last 3-year period was 77%.

Adult↗
PubMed1978

Partial purification of human kidney antigens.

A chromatographic method using immunoaffinity has been utilized in the search for kidney-specific antigens. After repeated absorptions by liver proteins coupled to a column of Sepharose CN-Br of a rabbit anti-human kidney serum, several antibodies remained. When these antibodies were coupled to a similar column and used for immunoaffinity chromatography, 8 kidney antigens, studied as peptides with molecular weights of 33,000, 80,000, 98,000 and 110,000-125,000 were obtained. They should not be found in similarly treated liver extracts.

Animals↗
PubMed1978

Determination of glomerular filtration rate in advanced renal insufficiency.

The glomerular filtration rate (GFR) has been determined in 17 patients with advanced renal insufficiency (GFR less than 15 ml/min) by different clearance techniques using creatinine, inulin and 51Cr-EDTA as filtration markers. With renal inulin clearance as reference method for GFR, endogenous renal creatinine clearance overestimated GFR by an average of 30%. Renal clearance of 51Cr-EDTA and inulin were closely correlated and thus 51Cr-EDTA is a suitable GFR marker even at low filtration rates. However, it was found that the plasma clearance of 51Cr-EDTA overestimated the GFR often by more than 100% in the range 2.6--11.2 ml/min. Renal clearance measured during 24 h was lower than 4 h renal clearance with the patient well hydrated and resting in bed. It is concluded that the precise measurement of low glomerular filtration rates requires the use of renal clearance techniques. Four-hour 51Cr-EDTA renal clearance is a suitable method for measuring and following the development of renal function in advanced renal insufficiency.

Adult↗