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Biomedical subjects

H Brückmann

Publications and source records attributed to H Brückmann.

79 records · Page 5Linked to original sources
PubMedDate not supplied

[Infarct of the basal ganglia in childhood--clinico-neuroradiologic findings and differential diagnosis].

Basal ganglionic infarctions during childhood are comparable in size and favourable prognosis with lacunary infarctions in adults. Considering their etiology they are comparable with capsular infarctions in adults. In four children with basal ganglionic infarctions and acute motoric hemiparesis, a quick and complete regression of clinical signs and CT-findings was observed. With regard to the differential diagnosis of basal ganglionic infarction we additionally report of a female patient with initially unilateral lesion who had silently developed the hemiparesis. In this case the clinical course and the neuroradiological follow-up findings suggested Leigh disease.

Adolescent↗
PubMedDate not supplied

[Clinical and neuroradiological findings in gliomatosis of the brain with special reference to magnetic resonance tomography].

We present three cases of GC, one belonging to the brainstem, and two belonging to the hemisphere type. Two cases were investigated by MRI. Tumour infiltration, while yielding only vague CT findings, was well demonstrated in MR studies where extensive hyperintense lesions were found in T2- and proton density images. In patients studied by MR these were localized within the white matter and corpus callosum. No enhancement was seen after administration of Gd- DTPA. These findings may strongly indicate the presence of gliomatosis cerebri, when clinical and laboratory data exclude inflammatory or neurodegenerative disease. Despite the good delineation of white matter changes stereotactic biopsy remains necessary to confirm the diagnosis of gliomatosis cerebri pathohistologically.

Adolescent↗
PubMedDate not supplied

[Cortical abnormalities of the brain. Morphologic and clinical findings].

Ten children at the age of 1-16 with various types of cortical dysplasias are demonstrated by means of computerized tomography. Clinical features of focal subcortical mass of heterotopic gray matter (focal pachygyria) are contralateral partial seizures (n = 5). Pachygyria commonly is associated with severe psychomotor retardation and epilepsy (n = 3). In two cases nodular heterotopias protruding the ventricular walls are accompanied by epilepsy only.

Adolescent↗
PubMedDate not supplied

Orbital venous congestion in childhood. Diagnostic and therapeutical implications.

A case study of 2 patients with venous congestion of the orbit due to different etiologies is presented. Both the children demonstrated orbital pain, proptosis, chemosis and conjunctival injection. In one case early diagnosis left to complete recovery by conservative treatment in a patient with a pyogenic cavernous sinus thrombosis. In the other case a traumatic carotid sinus cavernous fistula could be treated successfully using transvasculary navigated detachable balloons.

Arteriovenous Fistula↗
PubMedDate not supplied

Outcome of acute vertebrobasilar occlusions treated with intra-arterial fibrinolysis in 180 patients.

BACKGROUND AND PURPOSE: To evaluate predictors of recanalization and a favorable neurologic outcome in patients with acute vertebrobasilar occlusion (VBO) treated with local intra-arterial fibrinolysis (LIF). METHODS: The multicentric data of 180 patients with acute VBO treated with LIF were retrospectively evaluated. The modified Rankin scale (mRS) was used to evaluate the neurologic status before LIF and at the time of discharge. Patient's sex, age, etiology of VBO, recanalization, symptom duration before LIF, and pretreatment mRS were correlated with posttreatment mRS. Multiple logistic regression analysis was used to identify independent variables for recanalization and neurologic outcome. RESULTS: The overall mortality was 43%. Complete recanalization was achieved in 99 (55%) patients and a partial recanalization in 35 (19%) patients, respectively. Recanalization was significantly associated with a favorable outcome (P < .001). The success of recanalization was negatively correlated with the volume of the thrombus (P < .001). No correlation was found between site and etiology of VBO and recanalization. Neurologic outcome correlated strongly with the pretreatment mRS (P < .001) and also with age (P < .02). Coma lasting less than 4.5 hours led to a positive trend toward a better outcome after univariate testing (P < .001). CONCLUSIONS: Success of recanalization and neurologic status before treatment predict neurologic outcome in patients with VBO. Thrombus volume has an adverse effect on the recanalization success.

Acute Disease↗