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Biomedical subjects

H Bossart

Publications and source records attributed to H Bossart.

At least 37 records · Page 2Linked to original sources
PubMed1983

Systematic pH-measurements in the umbilical artery: causes and predictive value of neonatal acidosis.

Subpartal and neonatal blood gas analyses have attracted increasing interest during the past 20 years. Different studies have been carried out to investigate the causes and immediate consequences of perinatal acidosis. It was the aim of this study to examine the long term outcome of acidotic-born babies. During 16 consecutive months all deliveries in the Obstetric Department of the Centre Hospitalier Universitaire Vaudois (CHUV) were investigated with regard to incidence and causes of a perinatal acidosis (pHa.umb. less than 7.15). The psycho-motor development of all acidotic newborns was followed up for an average of 15 months. Out of 1922 deliveries a blood sample was available in all but 11 cases (0.57%). Seven newborns were excluded from the study on the assumption that their acidosis and outcome might be related to the underlying condition (congenital malformation and infection, extreme prematurity) rather than perinatal events. From the remaining 1904 deliveries 6.4% (N = 121) had a pHa.umb. less than 7.15 (Tab. I). The incidence of certain perinatal factors was compared in the acidotic and the non acidotic groups (Tab. II). The percentage of acidotic newborns is significantly higher in primipareae, in deliveries done on peridural analgesia in cord complications and premature rupture of the membranes, and in forceps deliveries. No difference could be found with regard to multiple pregnancies, meconiumstained amniotic fluid, cesarean sections, prematurity of 28-37 weeks, and sex. The relationship between CTG score and pHa.umb. is summarized in Tab. III.(ABSTRACT TRUNCATED AT 250 WORDS)

Acidosis↗
PubMed1979

[Place of routine amnioscopy in the screening of fetal distress (author's transl)].

In order to assess the benefits of routine amnioscopy in the screening of fetal distress, the CTG score, the pH of umbilical artery and the Apgar score were determined and compared in two groups of patients: one group had meconium stained amniotic fluid (MSAF), the other (control) had clear amniotic fluid. Although the prepathological and pathological CTG scores were more frequent in the MSAF group, the values of the umbilical artery pH had the same distribution in the two groups. The percentage of acidotic fetuses in the MSAF group is very low (2.9 p. 100) and practically the same as in the control group (2.5 p. 100). The Apgar score distribution at one and five minutes is also the same in the two groups. The distribution of CTG scores in acidotic fetuses is the same in the two groups, but the pre-acidotic fetuses born with meconial fluid have more often a pre-pathological or pathological CTG score. Fetuses with normal or suspect CTG-score and nevertheless acidotic or pre-acidotic pH values at birth are equally present whether the liquid is stained or not. Amnioscopy is therefore of no help even in this situation. In conclusion, the discovery of a MSAF is the manifestation of fetal hypoxia in only 2.9 p. 100 of cases: the detection of this condition is better achieved by CTG recordings than by routine amnioscopy.

Amniotic Fluid↗
PubMed1978

Clinical aspects of continuous tissular pH measurements of the newborn and the fetus.

The first results of continuous tissular pH readings in 58 neonates are presented. These results are compared with blood pH values and technical problems are discussed. The positive results made us proceed to sub-partu measurements. We finally give our opinion on the new ROCHE equipment and insist that it is not yet ready for routine use, but a promising tool for clinical research.

Adult↗
PubMed1978

[A new instrument for measurement of actual instantaneous pH in obstetric (author's transl)].

The authors present a new instrument for measurement of actual instantaneous pH in obstetrics. It has been developped to avoid most errors of the usual scalp-blood sampling. Its advantages are:--Aspiration is manual and controlled.--Results are obtained within 10--15 seconds. A comparative study with two other pH-meters has demonstrated an excellent correlation and reliability of this new instrument. The authors consider the method as simple, functional and reliable, all favourable factors for routine use.

Blood Specimen Collection↗
PubMed1976

[First evaluation of plasma L-lactate measurements by means of the "lactate analyzer 5400"].

The instrument used can measure lactate instantaneously by a semi-automatic method using an electrochemical-enzymatic sensor. In order to test the instrument, 3 series of measurements were carried out simultaneously by the Analyzer and by the conventional enzymatic method (Boehringer, Mannheim): "normal" plasma and "normal" blood was obtained from venous blood of healthy adults; pathological plasma, obtained by addition of a known concentration of lactate to normal plasma, was also tested. The correlation curves for these three series are reported. The coefficient r is between 0.95 and 0.98, which bears out the reliability of the measurements. Since a short period, this lactate analyzer is used in our research laboratory in obstetrics.

Autoanalysis↗