[CT study and standardised findings in occupationally-induced changes in the lungs and pleura with reference to the ILO 1980 classification of dust-induced pneumoconiosis].
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Biomedical subjects
Publications and source records attributed to H Bohlig.
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For the period from 1973 to the end of 1986, 70,656 data sets on occupational preventive medical examinations in employees exposed occupationally to asbestos dust (G 1.2) were made available to us by the Central Registry for Employees Exposed to Asbestos Dust (ZAS). On the basis of this data, an analysis of asbestosis risk was to be made in relation to specific areas of work, taking into consideration the beginning and duration of exposure. Proceedings for declaratory appraisal in accordance with occupational disease no. 4103 were instituted in 1760 cases in the report period. In accordance with the character of the available data, the X-ray findings in the lungs were available from the persons investigated as parameters of possible asbestosis risk on the basis of coding consistent with the International Pneumoconiosis Classification (ILO U/C 1971 and/or ILO 1980 West Germany). The major result of the statistical analyses on the mainframe macrocomputer of the University of Erlangen-Nuremberg was that the relatively highest risk of asbestosis was present in persons whose exposure began before 1955. On the other hand, with increasing duration of exposure, an unequivocal rise of the asbestosis risk could not be detected on the basis of the overall population. In relation to the individual fields of work, the relatively highest risk of asbestosis was shown to be in the asbestos textile and paper industry, as well as in the asbestos cement industry. No detectable risk of asbestosis was present in the fields of mining, traffic and health service and for women in the industrial sectors of building material, gas and water, catering trade, building, commerce as well as banking and insurance. Accordingly, it can be assumed that certain fields of work are or were exposed to such a small extent or not at all that a risk of asbestosis which is relevant in terms of occupational medicine is no longer to be assumed or was not to be assumed. This applies above all to certain work in the frictional coating (brake lining) and asbestos paper industry. Furthermore, the analysis of the data material did not provide any unequivocal indications that inhalative smoking habits have a negative effect on the risk of asbestosis. In principle, it can be stated that the occupational preventive medical investigations according to G 1.2 are effective.(ABSTRACT TRUNCATED AT 400 WORDS)
The radiographic appearance of the lateral pleura was divided into an upper, a middle, and a lower zone. Bilateral changes of the pulmonary layer of the pleura (diffuse pleural thickening) within the upper pleural zones were found in 863 (71%) of 1204 workers exposed to asbestos and in 249 (40%) of 622 non-exposed controls. Downwards along the chest wall this ratio of 7:4 increased progressively up to 10:1 at the lower parts of the pleura. Bilateral diffuse pleural thickening in at least two adjacent zones on each side was found in 652 (54%) of exposed and in only 86 (14%) of unexposed subjects. The difference was even more striking when comparing bilateral involvement of all three zones (28% and 3% respectively). Unilateral change was rare (4.8% and 7.8% respectively) and often due to causes other than exposure to asbestos. Pleural findings were the earliest radiographic features detectable associated with former exposure to asbestos. Bilateral diffuse thickening in at least two adjacent zones on each side seems to be a striking feature and an early indication of former occupational asbestos damage. Modifications of the International Labour Organisation 1980 classification are proposed.
The different sequelae of lung and pleura resulting from the inhalation of asbestos dust are discussed in detail, taking into consideration the improvements in dust-control measures. The use of Lung Dust Separation and Investigation and Radiological Classification of Pneumoconioses (ILO 1980) with regard to diagnostics is critically reviewed. Certain problems of compensation for asbestos-induced neoplasms are pointed out with special reference to the regulations of the Federal Republic of Germany.
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The latest version of the international classification of pneumoconiosis by the International Labour Office (ILO) in Geneva is presented, ie "ILO 1980 International Classification of X-Ray Findings in Pneumoconiosis", and is tabulated in detail. In connection with the specified modifications of the previous classification (ILO U/C 1971) initial critical assessments are made with particular reference also to the adaptation to conditions prevailing specifically in the Federal Republic of Germany.
The papers in this session, which are summarized briefly, do not cover the wide range of radiological and clinical problems resulting from inhalation of asbestos dust. Pleural effusions are found in persons exposed occupationally to asbestos, even in the absence of asbestosis, but they are difficult to attribute to such exposure. Asbestosis of the lung shows no striking symptoms and can also be diagnosed only after all other possibilities have been excluded. There are no convincing or striking morphological peculiarities that suggest that an 'asbestos lung cancer' exists. Mesotheliomas of the pleura and of the peritoneum are usually resistant to therapy of any kind, although several possibilities are discussed. Radiological surveillance is presented as being still the most effective and reliable method for medical surveillance of asbestos workers. Circumscribed pleural thickening is benign but a good indicator of exposure to mineral dusts. Diffuse pleural thickening occurs frequently in nonexposed groups and cannot, therefore, be used as an indication of exposure; however, it cannot yet be ruled out as being significant epidemiologically.
Radiographic follow-up studies of cases of silicosis serve as an example to illustrate the migration of nodular lung disease--in order to demonstrate the fact that silicotic pulmonary nodules with dense profusion tend to coalesce resulting in the formation of large opacities. More widely disseminated nodules with less dense profusion can--on the contrary--result in migration towards the periphery of the lung and thus mimick pleural disease by the formation of subpleural nodules.
For medical surveillance of dust workers, correlation of anatomical and radiological findings in silicosis and asbestosis is an assumption for computerized application of the ILO U/C 1971 classification of pneumoconiosis. The new regulations of insurance companies for preventive examinations in workers exposed to asbestos are described, and their results presented. Practicability and preliminary data suggest important information for the future.
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