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Biomedical subjects

H Boccalon

Publications and source records attributed to H Boccalon.

At least 91 records · Page 5Linked to original sources
PubMed1987

Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs.

Ninety-four patients suffering from venous insufficiency of the lower limbs participated in a multicenter, double-blind versus placebo study. After randomization, they were allotted for a treatment period of two months to one of three groups: TECA 120 mg/day, TECA 60 mg/day, or placebo. A significant difference (p less than 0.05) in favor of TECA was shown for the symptoms of heaviness in the lower limbs and edema, as well as for the overall evaluation by the patient. The venous distensibility measured by a mercury strain gauge plethysmograph at three occlusion pressures was improved for the TECA groups but aggravated for the placebo group.

Adult↗
PubMed1987

[Value of combining the thermal test with laser Doppler measurement of skin hemodynamics. Study of vascular acrosyndromes].

Different exploratory investigations of vascular acrosyndromes have failed to define their physiopathology. Capillaroscopy studies the specific morphologic aspects of certain connective tissue diseases, hemodynamic tests usually determine a global parameter, and those tests investigating cutaneous physiology alone come up against difficulties limiting their diffusion. The laser Doppler flowmeter (LDF) measures global skin flow in a reproducible, continuous simple manner, and was combined with standardized provocation tests during a prospective study to assess its value in angiology. The protocol involved a prospective study of 100 subjects during the winter 1984-1985: 21 healthy volunteers, 11 cases of acrocyanosis, 9 of acrorhigosis, 48 of Raynaud's phenomenon (22 primary and 26 secondary), 11 of connective tissue disease without Raynaud's phenomenon (table I). The LDD test measures skin microcirculation flow continuously in parallel with skin thermometry. Provocation tests included a standardized thermal test (fig. 1); the temperature is automatically reduced to 0 degree C in 15 minutes and then increased to 25 degrees C in 10 minutes in a jar into which the hand and forearm of the patients and any measuring captor are introduced. Respiratory provocation and additional pharmacologic tests were also completed. Interpretation of results involved calculation of the mean skin flow, Dm, pulsatile skin flow, Dp (fig. 2 and 3), at the basal state and then during temperature variations. The reference value of Dm is 2.741 +/- 0.378 V and is decreased in acrorhigosis, acrocyanosis and severe Raynaud's phenomenon. At 0 degrees C the decrease in Dm is 33 +/- 13% in healthy subjects. Specific values for different acrosyndromes and particularly the various types of Raynaud's phenomenon do not exist.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1987

[Subungual glomus tumors. Apropos of 2 cases].

Glomus tumours are uncommon, though not exceptional, benign growths developed from the constituents of the "neuromyoarterial glomus" initially described by Masson. Two cases of subungual glomus tumours of the hand in middle-aged women are reported. In spite of characteristic symptoms, with paroxysmal episodes of pain triggered off by cold and the most minute traumas, and of the finding in both cases of a violine++ tumour under the nail, the condition was belatedly diagnosed (7 and 27 years respectively after the onset of symptoms). Diagnosis rested not so much on standard radiography, which showed erosion of the distal phalanx in both patients, as on arteriography of the hand which displayed a small vascular pool at the arterial stage. Tumoral excision was successful.

Angiography↗
PubMed1987

[Variations in venous physiology in the healthy subject. Postural and venous occlusion plethysmography studies].

The principal characteristic of the venous network is its distensibility, the reason for its role as blood reservoir and cardiovascular adaptation system. This distensibility varies continuously as a function of venous tone, of neurocardiovascular adaptation and of the method used for its determination. The importance of variability of venous physiology was investigated by postural and venous occlusion plethysmography. Two series of tests were performed in 3 healthy volunteers, each being treated over one month: one series involved 19 determinations during May 1985, the other 14 determinations in December 1985. Two plethysmographic methods were employed: conventional venous occlusion plethysmography in decubitus with compression of 50 mm Hg and postural plethysmography with venous occlusion only, using gravity force during variations in position of subjects. Venous filling, a function of venous distensibility, varied between 16.7 and 17.8% during venous occlusion and 23.9 and 31.7% during postural plethysmography. Emptying half-life was from 20.7 to 40.7%. Emptying rate was, by the 6th second, 17.3 to 21.6% for venous occlusion and 27.3 to 32.3% for postural plethysmography. A relation was not found between results for the two methods, suggesting that they explore different phenomena. Variability of venous physiology parameters is marked, modulations being due to general or local factors, the former acting on both legs simultaneously: exterior temperature, neurocardiovascular physiology, digestion, stress, relaxation. Factors can have their effects reduced by differential study of the two limbs.(ABSTRACT TRUNCATED AT 250 WORDS)

Adaptation, Physiological↗
PubMed1986

[Computerized records in vascular pathology. II. Computer-assisted management of records in cerebrovascular pathology].

Computerized processing of data from patients with cerebro-vascular disease should improve interpretation of results of complementary examinations by allowing their comparison with arteriography and operative findings. It should also allow comparison of postoperative clinical and angiographic findings in order to analyse results obtained in an identical manner, and to provide a basis for discussion of therapeutic indications. Spontaneous evolution of atheromatous lesions can finally be compared with the course after surgery.

Cerebral Angiography↗
PubMed1986

[Computerized records in vascular pathology. III. Computer-assisted management in chronic arteriopathies of lower limbs].

Computerized processing of data from patients with chronic arterial disease of lower limbs has been an unsuccessful venture in many cases. This is due essentially to the complexity of the case-reports to be analyzed. In addition, the objectives are not the same if it concerns an angiologist or a vascular surgeon, or relates to an outpatient or hospital sector. Certain exploratory procedures such as Doppler and arteriography have not yet been the object of an agreement with respect to their results. An approach to the problem is proposed with respect to the polyvalent basic elements and then the more specific features as a function of the specific activity of the doctor concerned.

Angiography↗
PubMed1986

[Computerized records in vascular pathology. IV. Computer-assisted management in Raynaud's phenomenon].

The "dead finger" was first introduced into medical language in 1862 during the inaugural thesis of Maurice Raynaud: "of local asphyxia and symmetrical gangrene of the extremities". It has never ceased to stimulate interest since that date and to excite passionate speeches. Numerous reports of studies have been published since 1862 and "Raynaud's disease" has become a "syndrome", "phenomenon" or even "idiopathic disease" as a function of the author and the prevailing fashion, thus increasing the original confusion. However, it is now recognized that vasomotor disorders are not due to a single cause: apart from the primary forms of apparently purely spasmodic etiology, numerous affections accompanying these anomalies have been discovered.

Computers↗
PubMed1986

[Computerized records in vascular pathology. V. Computer-assisted management of records in venous pathology].

Computerized processing of data from patients with venous disease concerns mainly those with chronic venous insufficiency and venous thromboembolic disease. It is of particular interest for epidemiologic studies of venous disease, explorations (functional, phlebographic) and proposed therapies. Progress in these 3 sectors requires computerized processing of data from case-reports and standardization of the noting of these data.

Computers↗