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Biomedical subjects

H Black

Publications and source records attributed to H Black.

At least 37 records · Page 2Linked to original sources

A field evaluation of the efficacy of two vaccines against ovine pneumonic pasteurellosis.

Two vaccines against pneumonic pasteurellosis were evaluated for efficacy in lambs transported by sea from New Zealand to Saudi Arabia. One vaccine contained whole cell antigens of Pasteurella haemolytica A2 grown under iron restricted conditions. The other contained Pasteurella haemolytica A1 cell surface and leucotoxin antigens. There was no clear evidence of either vaccine leading to a lower pneumonia death or lesion rate than for the control group.

Journal Article↗

Rethinking recycling.

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Conservation of Natural Resources↗

The behaviour of male lambs transported by sea from New Zealand to Saudi Arabia.

The behaviour of two pens of mixed British breed male sheep transported by ship from New Zealand to Saudi Arabia was studied. One of the groups was carried above decks (n = 128) and one below decks (n = 116). Observations were conducted four to five times daily throughout the 24-day voyage. Over the whole voyage the most common activities were standing, lying and feeding. Overall, the animals adapted reasonably well to the shipboard environment, with most gaining weight. The mortality rate in the study pens averaged 2.5%, which was similar to that of the total shipment and average for this type of voyage. The behavioural measures appeared to provide sensitive indices of changes in the welfare of the sheep. An increase in lying activity, panting and drinking and a decrease in feeding during the latter part of the voyage were indicative of increasing heat stress. Plunging at the feed and water troughs led to loss of footing and increased the likelihood of smothering. This activity occurred after periods without feed or without water. Plunging also occurred when sheep moved towards the ventilators. Other factors associated with reduced well-being were the high stocking density which, combined with a wet faecal pad, limited movement towards feed or water and increased the likelihood of smothering.

Journal Article↗

The effect of salt and bentonite supplementation on feed and water intake, faecal characteristics and urine output in sheep.

The effects of the addition of salt (sodium chloride) and sodium bentonite to hay-based pelleted rations on feed and water intake, digestibility, the output of urine and faeces, and faecal consistency were evaluated under conditions resembling those used for the shipment of live sheep. The addition of salt to the diet had no effect on dry matter intake but increased water intake relative to controls (P<0.01), with commensurate increases in urinary output of more than 1 litre/sheep/day. The diet with bentonite plus salt resulted in a higher dry matter intake than controls (P<0.01). The addition of bentonite increased the faecal dry matter percentage (P<0.05). The effects of the additives on faecal water evaporative loss and hardness were not significant. A large variation (52.1-62.6%) between sheep in dry matter digestibility of feeds was not affected by treatment and this requires further investigation. It is recommended that salt not be added to diets used for live sheep shipments.

Journal Article↗

Ophthalmic pain following cataract surgery: a comparison between local and general anaesthesia.

Ophthalmic pain following uncomplicated extracapsular cataract surgery was assessed postoperatively in 61 patients; 55% undergoing ophthalmic surgery had no pain or discomfort postoperatively, and 32% reported slight discomfort. Approximately 8% of patients reported mild pain and the remaining 5% experienced moderate to severe pain. Local anaesthesia was shown to be more comfortable postoperatively than general anaesthesia in the immediate postoperative period with both groups receiving similar amounts of postoperative analgesics.

Acetaminophen↗

Chronic copper poisoning in Angora kids.

The investigation of five field cases of chronic copper poisoning in a group of 100 Angora kids is reported. Toxicity was confirmed by the demonstration of Heinz body anaemias, necrotizing liver disease, haemoglobinuric nephrosis and excessive levels of copper in blood, livers and kidneys. The dietary history of the kids is described. Tissue levels of copper and reported interactions between selenium, zinc and copper are discussed. Therapeutic and preventative measures are suggested.

Journal Article↗

The effect of dietary fish oil supplementation on psoriasis. Improvement in a patient with pustular psoriasis.

An open study testing the effects of fish oil supplementation on psoriasis in 26 patients is described. None of the patients with plaque-type psoriasis vulgaris showed clinically significant improvement; however, a patient with generalized pustular psoriasis showed marked improvement with the fish oil supplementation. In this patient, scale leukotriene B4 levels were determined and shown to be significantly decreased after completion of the study, but the leukotriene B4 levels did not correlate with her clinical course. The results of our study are contrasted with those of a recent study that did show beneficial effects of fish oil supplementation on plaque-type psoriasis.

Adult↗

White liver disease in goats.

Three field cases of ill-thrift, hepatic lipodystrophy and low tissue levels of vitamin B12 in young angora cross goats are reported. The cases meet the criteria for the diagnosis of white liver disease (WLD) described for sheep. The hypothesis that WLD is a metabolic consequence of cobalt/vit B12 deficiency in sheep and goats on a diet rich in propionate is developed, together with possible reasons for its occurrence in these species but not in cattle or red deer.

Journal Article↗

A double-blind parallel trial to assess the efficacy of doxazosin, atenolol and placebo in patients with mild to moderate systemic hypertension.

The antihypertensive and lipid effects of doxazosin and atenolol were compared in a 10-week, double-blind, parallel, placebo-controlled study. The 129 adults enrolled had mild to moderate hypertension (average supine diastolic blood pressures for doxazosin, atenolol and placebo were 100.6, 101.0 and 99.7 mm Hg, respectively). Patients were randomly assigned to treatment with doxazosin, 1 to 16 mg daily, atenolol, 50 to 100 mg daily or placebo. Among 114 patients included in the efficacy analysis, standing blood pressure (systolic/diastolic) changed by -13/-11 mm Hg with doxazosin (n = 37), -12/-12 mm Hg with atenolol (n = 39) and +1/-1 mm Hg with placebo (n = 38). Mean reductions in blood pressure for doxazosin and atenolol were significantly greater than those for placebo (p less than 0.01), although no statistically significant differences between the active agents were noted. Serum lipid measurements were evaluable for 116 patients, and the 38 doxazosin-treated patients in this group experienced reductions in total cholesterol, total triglyceride and very low density lipoprotein cholesterol levels. Both doxazosin and atenolol demonstrated comparable acceptance profiles. Doxazosin is an effective hypotensive agent with beneficial effects on serum lipid levels.

Adrenergic alpha-Antagonists↗