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Biomedical subjects

H Bismuth

Publications and source records attributed to H Bismuth.

At least 523 records · Page 29Linked to original sources
PubMedDate not supplied

Mesenteric panniculitis of the mesoappendix.

A rare case of mesenteric panniculitis mimicking appendicular mass is presented. At laparotomy panniculitis localized in the mesoappendix and concomitant chronic appendicitis were found. A pathogenetical association is suggested by the Authors. The need for careful follow-up is stressed.

Aged↗
PubMedDate not supplied

[Rejection of discordant xenografts of the liver and heart].

Comparative study of the rejection of 26 heart and liver xenografts in strain discordant combination (guinea pig/rat lewis) allows the authors to establish the liver's weakest sensibility to natural xenoantibodies, the modesty of histological signs on liver xenograft rejection, and these lost's more longer survival. The results are compared to those obtained with 26 heart and liver isografts.

Animals↗
PubMedDate not supplied

[Cyclosporin, toxicity and efficacy in rejection of liver allografts in the rat].

52 orthotopic liver transplants were performed in DA to lewis rat strain combination, in order to appreciate cyclosporine toxicity, and efficacy at doses of 10 mg/kg day (G II) and 20 mg/kg/day (GIII) compared to liver allografts in DA/lewis rats. The first signs of cyclosporine hepatotoxicity are biological (increased plasma level of bilirubine and transaminase) that were noticed at the dose of 20 mg/kg/day. Histological signs (cells inclusion, hepatocytic necrosis) appeared late and were less constant as well as difficult to assert creatinine plasma level was the best reflect of cyclosporine nephrotoxicity. Renal toxicity was practically constant at the dose of 20 mg/kg/day. In spite of renal and hepatic toxicity, cyclosporin by itself, allows the abolition of the acute rejection of liver allografts in the rat.

Animals↗
PubMedDate not supplied

[Surgical treatment of hilus cancers].

Carcinomas of the hilus are malignancies which obstruct the upper part of the bile duct, including the Klatskin tumour but also neighbouring carcinomas invading the hilus and obstructing the biliary tract at this level. The aim of the treatment is to remove the tumour but in our experience, this radical treatment can be accomplished in only 10% of the carcinomas of the hilus. Therefore, the treatment is in the majority of the cases only palliative and the technique the authors used is the intrahepatic cholangio-anastomosis between the duct of Segment III and a Roux-en-Y jejunal loop by the approach of the intrahepatic duct in the Round Ligament fissura. In 61 cases of intrahepatic cholangioanastomoses, performed for the majority according this technique, the mortality was 6.5% and the mean survival 10.3 +/- 2.7 months with extremes of 2 to 72 months. The large variability of this survival is not in relation with the quality of the anastomosis but with the extent and the evolutivity of the carcinoma. Among the surgical and non-surgical palliative treatments of carcinomas of the hilus, the intrahepatic cholangio-anastomosis is the procedure which gives the best comfort and less iatrogenic complications.

Bile Duct Neoplasms↗
PubMedDate not supplied

[Peroperative echography in hepatobiliary surgery].

Intra-operative ultrasound allows to know precisely the intra-hepatic vascular anatomy and, by defining the precise relationship between tumor and vascular structures, has modified the therapeutic strategy in surgery of hepatic tumors. In biliary surgery, this procedure is useful in intrahepatic lithiasis. In surgery of digestive cancer, it permits to detect unknown hepatic metastases which may change the type of surgery indicated.

Biopsy, Needle↗
PubMedDate not supplied

[Peroperative echography in hepatobiliary surgery].

Intra-operative echography provides precise information on anatomy of the liver and accurately locates hepatic tumours, even small ones, thereby improving the operative strategy. It is most useful in biliary surgery for detection and treatment of intrahepatic lithiasis. By displaying undetected hepatic metastases, echography of the liver is of considerable value in surgery of common tumours of the digestive tract.

Biliary Tract Surgical Procedures↗
PubMedDate not supplied

[Acute necrotic pancreatitis: toward restriction of surgical indications].

Fifty-two patients operated for acute necrotising pancreatitis are reported. All severely-ill patients, operated early in order to perform a necrosectomy, died subsequently. Patients without severe illness were operated either for a complication of their pancreatic necrosis or electively for biliary lithiasis. The postoperative mortality was 29 p. 100 and 0 p. 100 respectively. Pancreatic necrosectomies were associated with a high morbidity whether performed for complications (64 p. 100) or during elective biliary surgery (33 p. 100). From this study, it appears that there is no indication for early necrosectomy in the severe forms of acute necrotising pancreatitis. However, pancreatic abscess remains a formal indication for drainage. It seems also justified to perform elective surgery without necrosectomy for biliary lithiasis complicated by acute necrotising pancreatitis.

Acute Disease↗