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H Bihl

Publications and source records attributed to H Bihl.

63 records · Page 4Linked to original sources
PubMed1986

Detection of carotid thrombi with indium-111 platelet scintigraphy.

In order to prove that platelet scintigraphy (PSC) is able to detect carotid thrombi formations, we performed PSC in 15 patients directly before or immediately after a percutaneous carotid angiography. PSC was successful in demonstrating iatrogenic fresh carotid thrombi in 13 out of 15 cases. Out of 53 patients with cerebrovascular disease and carotid stenosis a pathologic platelet accumulation was seen in 39 carotid arteries, 31 on the symptomatic side; more often in slight- and middle-sized stenoses than in high degree stenoses. We assume that in these cases PSC detected carotid thrombi which caused arterio-arterial emboli.

Angiography↗
PubMed1985

[Sarcoidosis (Boeck disease) of the parotid gland].

Involvement of the parotid gland with sarcoidosis occurs in 1-6% of the patients. In rare cases parotitis represents the initial clinical manifestation of sarcoidosis. In that case, the otorhinolaryngologist is usually the first to be confronted with this disease and may enable an early diagnosis and therapy. In the present paper a rare case of isolated sarcoidosis of the parotid gland is reported. The results obtained by different examination techniques are demonstrated and their relevance for the diagnosis of sarcoidosis is discussed.

Adult↗
PubMed1984

[Computed tomography and scintigraphy in malignant pheochromocytoma].

Two patients with malignant metastasising phaeochromocytomas are described. Special attention is paid to the findings on computed tomography and scintigraphy with meta-I-benzylguanidine. The scintigraphic findings are not uniform. A review of the literature has shown that the sensitivity of scintigraphy is less for malignant phaeochromocytomas than it is for benign tumours.

3-Iodobenzylguanidine↗
PubMed1983

Liver tissue characterization using computerized echography.

A digital echographic data acquisition and evaluation system was used in a clinical study including more than 100 patients with various local or diffuse liver tissue alterations. For diagnosis two decision methods are applied: first linear discriminant analysis and second a Bayesian method. Each A-scan is represented by a set of various numerical parameters from which only the most signal-distinctive ones are used for evaluation. The diagnostic results which will be presented and discussed have proved the method to be very sensitive and specific.

Diagnostic Errors↗
PubMedDate not supplied

Effect of radioactive iodine therapy on parotid gland function.

In 37 males and females with thyroid carcinoma, treated with radio-iodine, parotid gland function was investigated before and one week after therapy. 34 subjects remained free of complaints and showed no effect of 131I-therapy on parotid flow rate. Following therapy, all of them showed alterations in the composition of parotid secretion, especially enhanced values for alpha-amylase activity, protein concentration and sodium concentration. Three subjects developed acute parotitis of the obstructive sialadenitis type. In these patients, flow rate was severely reduced. The values for PHI, sodium, alpha-amylase and protein in parotid saliva were markedly elevated. Just as in chronic recurrent parotitis, increased activity of salivary glandular kallikrein in radio-iodine sialadenitis was measured.

Female↗
PubMedDate not supplied

Efficient symptomatic control of carcinoid tumors with somatostatin in patients with disease progression under alpha-interferon therapy.

BACKGROUND/AIMS: We report--as a retrospective observation--on eight patients with malignant carcinoid tumors. MATERIALS AND METHODS: All patients were initially treated with alpha-interferon and received the longacting somatostatin analogue octreotide (SMS 201-995) after disease progression. Tumor growth was monitored by CT-scan or ultrasound. In addition, serum CgA and urinary 5-HIAA values were determined. RESULTS: All patients responded with relief of symptoms within a few days after the start of octreotide therapy. A regression of the tumor size did not occur, however four patients showed no significant progress over a period of nine to more than eighteen months. The endocrine parameter chromogranin A--determined by immunoluminometric assay (ILMA)--was elevated in all eight patients regardless of symptoms and showed a close correlation with the course of disease. The urinary 5-HIAA values were only elevated in seven patients. In addition, 123I-SMS 204-090 scintigraphy could be performed in six patients. Using this method most of the primary tumors and metastases could be detected. CONCLUSIONS: Only octreotide therapy showed a sufficient symptomatic control and has to be considered as progress in drug therapy for patients with malignant carcinoid tumors. In addition, chromogranin A is an interesting endocrine parameter for the follow-up of the secretory activity.

Aged↗
PubMedDate not supplied

Comparison of MIBG and pentetreotide scintigraphy in children with neuroblastoma. Is the expression of somatostatin receptors a prognostic factor?

BACKGROUND: Neuroblastoma (NB) is the fourth most common pediatric malignancy and recent reports suggest a prognostic role of somatostatin receptor scintigraphy (SRS) in this disease. MATERIALS AND METHODS: Twenty two patients (pts. mean age 43.9 months) with NB were investigated by 1-123-MIBG and SRS (In-111-pentetreotide). Twenty-seven comparative scans were evaluated and compared for catecholamin excretion, Ultrasound, CT and MRI data. The patients were then divided into three groups. I: patients with manifest disease, II: patients with relapse or minimal disease and III: patients with no evidence of disease. RESULTS: MIBG and SRS scans were concordant in 85% (12 true positive, 7 true negative, 4 false negative). In 4 pts only the MIBG scan was positive. In 9 pts with stage I-III disease or complete remission no relapse was recorded during 19.8 months. In 4 out of 5 pts who died SRS failed to localize the tumor sites but three MIBG scans were positive. Five out of 6 pts with a relapse free interval of 7.9 months had positive SRS and MIBG scans. CONCLUSIONS: in NB SRS can be applied as a specific imaging modality. However, in some pts SRS failed due to the lack of receptor expression. Somatostatin receptor expression seems to be related with a more favourable clinical outcome.

3-Iodobenzylguanidine↗