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Biomedical subjects

H Betz

Publications and source records attributed to H Betz.

At least 289 records · Page 16Linked to original sources

Formation of a complex between yeast proteinases A and B.

Sephadex G-100 gel filtration of a purified mixture of tryptophan-synthase-inactivating enzymes I and II from Saccharomyces cerevisiae, which had previously been identified as yeast proteinases A and B, yields two coincident peaks of tryptophan-synthase-inactivating activity and proteinase A and B activities. The peaks correspond to molecular weights of approximately 100 000 and 50 000. It could be demonstrated, with purified proteinases A and B, that the high molecular weight peaks is due to the formation of a stoichiometric complex between proteinases A and B. The AB complex can easily be separated into its constituent enzymes by DEAE-Sephadex chromatography. When in the AB complex, proteinase B molecules still bind the specific proteinase B inhibitor from yeast.

Macromolecular Substances↗

[Liquor-scintigraphic findings with Yb 169-DTPA in cerebro-atrophic processes].

Liquor-scintigraphic examinations were carried out with Yb 169-DTPA in two patients, who were offering - clinically as well as by pneumo-encephalographic findings - the picture of a cerebro-atrophic process. Especially the first case showed the typical course and symptoms of Alzheimer's disease. A "stasis" of the radionuclide, lasting for 48 hours, was manifesting liquor-scintigraphically herein, in the course of which there was - initially - a weak representation of the ventricles. However, the complete clinical picture of a communicating hydrocephalus did not show up. In the second case, an undisturbed liquor circulation and absorption, to a great extent topically and temporally undisturbed, were observed. The question arises whether Alzheimer's disease is manifesting together with such a disturbance of the liquor circulation, already described also by other workers. The second case makes clear that the liquor space scintigraphy cannot be used as only diagnostic method in all cerebro-atrophic processes.

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