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Biomedical subjects

H Berndt

Publications and source records attributed to H Berndt.

At least 55 records · Page 3Linked to original sources
PubMed1990

Laser light transmission and laser Doppler blood flow measurements on the human, rat and guinea pig cochlea.

In order to test the applicability of laser-Doppler flowmetry in monitoring cochlear blood flow clinically, the thickness and the helium-neon laser light transmission of specimens of human, rat and guinea pig promontory bone and human skin were determined. Furthermore, comparative laser-Doppler measurements were taken from the promontory in patients, rats and guinea pigs. Due to the different thicknesses of the promontory bone in different species, the light transmission was found to be considerably higher for the animal cochlea (rat, 15%; guinea pig, 6.6%) than the human cochlea (1.7%). However, a clearly higher laser-Doppler signal was recorded from both the human and the rat cochleas as compared with the guinea pig. The relative laser light attenuation by the human skin specimens corresponded to that of the human promontory bone. The findings are discussed with regard to the suitability of the laser-Doppler method for blood flow measurements in the human cochlea.

Aged↗
PubMed1990

[Prevalence of cholelithiasis in relation to use of hormonal contraceptives].

UNLABELLED: 400 women in continuous care of a family planning clinic were examined for gallbladder stones by standard ultrasound technique. Gallstones (GS) are found infrequently in nulliparous women (3.1 percent). The prevalence of GS increases with number of births and with age: 11 percent of female under 25 years of age, who have ever born, have GS; women aged 45 years and older who have born two or more children have GS in 35 percent. Duration of use of HC increases with rising age and with number of births. There is no regular relationship between duration of use of HC or total dose respectively and prevalence of gallbladder stones. CONCLUSION: Intake of HC has no or only a marginal influence on prevalence of gallbladder stones.

Adult↗
PubMed1990

[Effect of an angiogenesis-promoting dipeptide on microcirculation in experimental chronic stomach ulcer in the rat].

The influence of an angiogenesis stimulating dipeptide (Lys-Pro-derivative) on the blood flow rate of the stomach was tested in rats suffering from ulcus ventriculi by microspheres technique. 21 days after operation (acetic acid model by Takagi) the ulcers in the group treated with the dipeptide were healed completely, but not in the control group. The higher blood flow in the ulcer area of the dipeptide group radiometrically gained, was not changed significantly (U-test by Man-Whitney). These results demonstrate, that the process of rapid wound healing promoted by the dipeptide cannot entirely be explained by a higher blood flow of the stomach.

Angiogenesis Inducing Agents↗
PubMed1990

[Epidemiology of gallbladder calculi in young females].

In a population sample of nearly 900 women aged less than 25 years, prevalence of gallbladder stones (GS) was estimated by ultrasound and some risk factors were analyzed. GS were found in 4.8 percent. The prevalence of GS is significantly higher in females with GS in the family history as compared to persons without known GS in the family (11.8 vs. 2.6 percent); in women who have born as compared to nulliparae (10 vs. 3 percent); in obese women (BMI 26 or higher) as compared to lean women (15.1 vs. 4.2 percent). There was no significant correlation between intake of oral contraceptive and prevalence of GS.

Adult↗
PubMed1989

[Familial incidence of gallstones].

From March 1986 to June 1988 ultrasound examinations for gallstones were performed on 1616 symptom-free persons (982 females and 634 males, aged 12-93 years). They were also asked about gallstones and (or) cholecystectomy among blood relatives. Gallstones were discovered or a previous cholecystectomy was reported in 316 persons (19.6%). The prevalence of gallstones was age-dependent and increased with age. Prevalence was higher in females than in males. There was, in this group of 316, a significant increase in family prevalence of gallstones among six of nine age-groups (P less than 0.05 and P less than 0.01, respectively) compared with those without gallstones. These data suggest a genetic disposition towards cholelithiasis, while dietary factors could not be definitely excluded.

Adolescent↗