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Biomedical subjects

H Baden

Publications and source records attributed to H Baden.

At least 37 records · Page 2Linked to original sources
PubMed1987

Implantation of a pressure cuff around the subphrenic oesophagus.

The possibility of implanting a pressure cuff around the subphrenic oesophagus as a barrier to reflux was tested in six pigs. The oesophagus tolerated cuff pressures from 48 to 95 cmH2O, corresponding to intra-oesophageal pressures from 27 to 75 cmH2O. The pigs with the perioesophageal cuff swallowed a solid diet without difficulty. However, dysphagia occurred in pigs kept alive for more than a month and the main reason was malfunction of the device because of surrounding fibrosis. This problem should be solved before implantation of the device in humans is attempted.

Animals↗
PubMed1987

Uncombable-hair syndrome.

Four children had short, unmanageable, pale blond hair. They had no associated abnormalities and no family histories of abnormal hair. Light microscopy of the hair was normal in three patients, with pili torti present in the fourth. Electron microscopy of hairs from all four children revealed longitudinal grooves in the hair shaft, diagnostic of uncombable-hair syndrome.

Child↗
PubMed1986

Pancreatic pseudocysts during first attack of acute pancreatitis.

One hundred and forty-eight patients admitted with their first episode of acute pancreatitis were examined by ultrasonography. During the acute attack 1 or more pseudocysts were found in 19 patients (13%), pancreatic abscess in 2, whereas 127 had a normal or swollen pancreas. Two small cysts resolved spontaneously, eight were cured after ultrasonically guided needle aspiration or catheter drainage, and cystogastrostomy was necessary in four cases. One patient refused treatment. Abscesses requiring surgical drainage developed in four of the patients with pseudocysts. The study showed that pseudocysts may appear as early as within 1 week of the first episode of acute pancreatitis. Some pseudocysts may resolve spontaneously, and ultrasonically guided aspiration or drainage may cure approximately half of the pseudocysts.

Acute Disease↗
PubMed1984

Hartmann's operation as an emergency procedure for perforation of the sigmoid colon. A consecutive series.

A consecutive series of 19 patients with acute perforation of the sigmoid colon, were subjected to Hartmann's procedure. The rationale for primary resection of the diseased segment of the bowel is to remove the source of sepsis. The operation took approximately 2 1/4 hours, the temperature was normalized within 2 days and the hospital stay was 22 days. The perforations were caused by cancer in 4 patients. Half of the patients developed postoperative complications, mainly wound sepsis. There was one postoperative death, caused by pulmonary embolism. Approximately three months later a colorectal anastomosis was performed on 11 patients. Our experience confirms that Hartmann's procedure is the treatment of choice for patients with acute perforation of the sigmoid colon.

Adult↗
PubMed1982

Sclerotherapy of bleeding esophageal varices. Long-term results.

Sixty-one patients presenting with hemorrhage from esophageal varices were treated with sclerotherapy by means of a fiberoptic endoscope. Twenty-nine had acute bleeding, which was stopped in 90%. Thirty-two were treated after recent bleeding. The hospital mortality was 31%. Re-bleeding occurred in 55% of those discharged but was easily controlled. Fatal complications occurred in 5%. The calculated 4-year survival was 35%. Two thirds of this mortality could be attributed to liver failure. The intellectual function of the patients appeared to be unaffected.

Adult↗
PubMed1981

Myosin light chains and the developmental origin of fast muscle.

Physiological characteristics of embryonic and fetal fast muscle function are similar to those of adult slow muscles, whereas most biochemical data suggest that embryonic and fetal fast muscles contain only fast muscle myosin. In the studies reported here, myofibrillar preparations from developing avian pectoral muscle (fast muscle) were isolated and analyzed for myosin light-chain type and synthesis. These analyses show that early in development avian fast muscle synthesizes and assembles myofibrils with light chains of both slow and fast myosins. Later in development, fast muscle no longer assembles myofibrils containing slow myosin light chains due to the cessation of synthesis of slow myosin light chains in mid-development. These in vivo studies indicate that the more developmentally primitive type of skeletal muscle is one that synthesizes both slow and fast myosin light chains independent of its anatomic location, and an event(s) late in fast muscle development results in the repression of synthesis of slow myosin light chains.

Aging↗