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Biomedical subjects

H B Wheeler

Publications and source records attributed to H B Wheeler.

78 records · Page 5Linked to original sources
PubMedDate not supplied

Diagnostic methods for deep vein thrombosis.

Clinical diagnosis of deep vein thrombosis (DVT) is unreliable, and treatment should not be undertaken without objective confirmation. The traditional 'gold standard' for the diagnosis of DVT has been venography, but ultrasonic imaging has now replaced venography as the new diagnostic standard in many hospitals. A variety of noninvasive physiologic tests are also useful in selected circumstances. These include plethysmography, Doppler flow studies, radioisotope tests, thermography and peripheral blood tests which reflect activation of coagulation or thrombolysis. We describe the clinical application of these diagnostic procedures, both for symptomatic patients suspected to have DVT and for asymptomatic patients at high risk for DVT. The selection of an appropriate diagnostic modality depends upon institutional capabilities, cost-effectiveness and individual patient circumstances.

Computer Systems↗
PubMedDate not supplied

Venous occlusion plethysmography for the detection of venous thrombosis.

Venous occlusion plethysmography (VOP) was originally developed to study the physiology of the arterial circulation in the extremities. Improvements in plethysmographic instruments have now made bedside evaluation of peripheral hemodynamics feasible. In recent years, VOP has been employed for the detection of deep vein thrombosis. Combined analysis of the venous volume increase and the subsequent venous outflow in 3 sec, and measured by impedance plethysmography, has produced a 95% correlation with venography in detecting thrombosis of the popliteal, femoral, and iliac veins in 390 limbs. The method is inadequate for detection of isolated calf thrombi.

Blood Circulation↗
PubMedDate not supplied

Noninvasive detection of axillary and subclavian venous thrombosis by impedance plethysmography.

Venous occlusion impedance plethysmography (IPG) is an objective noninvasive test which is widely employed for the detection of deep venous thrombosis (DVT) in the lower extremities. The IPG technique is easily adapted to the evaluation of upper extremity venous thrombosis, as demonstrated in 46 patients with symptoms of axillary and subclavian venous thrombosis (88 limbs) and 26 normal volunteers (52 limbs). Venograms were obtained in 18 patients (22 limbs) and correlated in all cases with the previous IPG interpretation. The test procedure and interpretation criteria for the noninvasive detection of upper extremity deep venous thrombosis are similar to those previously developed for the lower extremities, but with more emphasis on comparison with the contralateral limb. Vascular laboratories performing IPG for lower extremity DVT should be able to employ this test for the detection of upper extremity venous thrombosis as well.

Adolescent↗