[International expert consensus on gene therapy for hereditary hearing loss: based on clinical trials].
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Journal Article↗
Biomedical subjects
H B Shi
Publications and source records attributed to H B Shi.
A highly efficient method for staining ultrathin sections.
A simple and efficient staining method to handle simultaneously thirty (or even more) electron microscope grids with ultrathin sections is described. The device applied is easily constructed from inexpensive and readily available materials but can bring easily high quality staining results, and the amount of stain and washing water required is very small.
Microscopy, Electron↗
[Capsular bag implantation of IOL].
The authors performed capsular bag implantation of IOL in 57 patients (65 eyes); the visual acuities were 0.5-1.5 in 90.5% of the eyes on follow-up. The actual procedure, the points of note and improvements in technique were described, and the 2 modalities of posterior chamber IOL implantation were commented upon.
Adolescent↗
[Anti-inflammatory and anti-allergic action of aloperine].
Aloperine, an alkaloid isolated from Sophora alopecuroides L, showed a marked suppressive effect on the swelling of the rat's hind paw induced by injecting carrageenin, macostatin, PGE2, histamine, 5-HT, on the rat's scald oedema induced by scalding its hind paw, and on the increased permeability of capillaries caused by histamine and the leukocytic migratory response. The swelling induced by injecting carrageenin into the hind paw of adrenolectomized rats was still significantly inhibited. Noticeably, aloperine reduced the content of PGE and histamine in the exudate formed after injecting carrageenin and dextran into the rat's hind paw, and increased the stability of red cell membranes, the activity of catalase (CAT) in hepatic tissue of mice, and reduced the content of malondialdehyde (MDA) in hepatic tissue of intoxicated mice. It had no apparent effect either on the activity of superoxide dismutase (SOD) in mice serum or on the phagocytosis of the monocyte-macrophage system, or on Forssman cutaneous vasculitis and the content of immune complex in serum of rats with Arthus reaction. But it had certain inhibitory effect on the PCA reaction and significant inhibitory effect upon such allergic reaction as Arthus reaction, reversible passive Arthus reaction, the delayed hypersensitivity reaction induced by tuberculin in rats, and adjuvant arthritis.
Alkaloids↗